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New antibody-drug conjugate shows promising activity in salivary gland tumors

The antibody-drug conjugate ado-trastuzumab emtansine (T-DM1) has promising activity in HER2 amplified salivary gland tumors, according to data published in the Annals of Oncology.

7 Jan 2020

New molecular mechanism can reverse genetic defect responsible for Friedreich's ataxia

Scientists at Tufts University have identified a molecular mechanism that could reverse the genetic defect responsible for Friedreich's ataxia, a neurodegenerative disease that leaves its victims with difficulty walking, a loss of sensation in the arms and legs and impaired speech caused by degeneration of nerve tissue in the spinal cord.

6 Jan 2020

Researchers discover glioblastoma origins using brain organoids

Glioblastomas are the most aggressive form of brain cancer - they grow and spread rapidly through the brain and are virtually impossible to eradicate, typically leading to death within one or two years of diagnosis.

6 Jan 2020

E-cigarette users have reported adverse health effects online for at least seven years

A team of researchers at the University of California, Riverside, used automated computer methods to mine a large online discussion forum for electronic cigarette users and found this group reported numerous adverse health effects for at least seven years.

6 Jan 2020

Study hints a link between disruptions to progesterone signaling and recurrent miscarriage

About twenty percent of confirmed pregnancies end in miscarriage, most often in the first trimester, for reasons ranging from infection to chromosomal abnormality.

6 Jan 2020

ART may not be completely effective in restoring immune protection, study suggests

A study led by researchers from SUNY Downstate Health Sciences University and Oregon Health & Science University, published in the Journal of Infectious Diseases, showed that, despite successful antiretroviral therapy, antigen specific memory to vaccinations that occurred before HIV infection did not recover, even after immune reconstitution.

6 Jan 2020

New clinical study to test retinal screening processes for early detection of Alzheimer's disease

The University of Rhode Island, in collaboration with BayCare Health System in Florida and The Memory and Aging Program at Butler Hospital, an affiliate of The Warren Alpert Medical School of Brown University, is launching a clinical trial of retinal screening processes that could help clinicians detect Alzheimer's disease possibly two or more decades before patients develop life-altering clinical symptoms.

6 Jan 2020

Body clock gene impairs defense against pneumonia

Most living things have an internal body clock which regulates when they sleep and when they wake up. A complex set of genes turning on and off, make this body clock run over roughly 24 hours, and a gene known by the acronym BMAL1 is one of the master regulators of this clock, controlling many other body clock genes and pathways.

6 Jan 2020

Discovery of cellular 'hands' could have implications in the fields of cell, developmental biology

The protein, called syndecan-4, combines with fellow cell membrane proteins, called integrins, to form protruding 'hands' that sense the environment outside the cell.

6 Jan 2020

Researchers develop new way to fight late-stage sepsis

Researchers have developed a way to prop up a struggling immune system to enable its fight against sepsis, a deadly condition resulting from the body's extreme reaction to infection.

6 Jan 2020

Certain cancer drugs could be used in the future to treat COPD

New research has shown the potential for clinically available cancer treatments to treat chronic obstructive pulmonary disease.

6 Jan 2020

Researchers reveal how antibodies assemble to form a circle for defensive attack

Antibodies are key players in our immune system. These antibodies recognize antigens displayed on foreign cell membranes and thereby recruit attacking forces, called complements.

6 Jan 2020

Aspirin’s benefits may extend beyond heart health to colorectal cancer treatment

The benefits of a daily aspirin may extend beyond heart health to colorectal cancer treatment, say City of Hope researchers who have found aspirin appears to reduce tumor growth and inhibit recurrence of the disease.

6 Jan 2020

Effort to control opioids in an ER leaves some sickle cell patients in pain

India Hardy has lived with pain since she was a toddler — ranging from dull persistent aches to acute flare-ups that interrupt the flow of her normal life.

6 Jan 2020

Study may explain how chemicals in skincare products trigger allergic contact dermatitis

Allergic reactions in the skin can be caused by many different chemical compounds found in creams, cosmetics, and other topical consumer products, but how they trigger the reaction has remained somewhat mysterious.

3 Jan 2020

Bile acids could also play a role in immunity and inflammation

Could bile acids--the fat-dissolving juices churned out by the liver and gallbladder--also play a role in immunity and inflammation?

3 Jan 2020

FDA needs to take further action on e-cigarettes

While the American Thoracic Society appreciates that the FDA took action on certain flavored cartridge-based vaping products, it is disappointed that the Administration chose to not follow through on its September 2019 promise to clear the market of all flavored electronic nicotine delivery projects.

3 Jan 2020

Cell News and Research

New antibody-drug conjugate shows promising activity in salivary gland tumors

New molecular mechanism can reverse genetic defect responsible for Friedreich's ataxia

Researchers discover glioblastoma origins using brain organoids

E-cigarette users have reported adverse health effects online for at least seven years

Study hints a link between disruptions to progesterone signaling and recurrent miscarriage

ART may not be completely effective in restoring immune protection, study suggests

New clinical study to test retinal screening processes for early detection of Alzheimer's disease

Body clock gene impairs defense against pneumonia

Discovery of cellular 'hands' could have implications in the fields of cell, developmental biology

Researchers develop new way to fight late-stage sepsis

Certain cancer drugs could be used in the future to treat COPD

Researchers reveal how antibodies assemble to form a circle for defensive attack

Aspirin’s benefits may extend beyond heart health to colorectal cancer treatment

Effort to control opioids in an ER leaves some sickle cell patients in pain

Study may explain how chemicals in skincare products trigger allergic contact dermatitis

Bile acids could also play a role in immunity and inflammation

FDA needs to take further action on e-cigarettes

Study shows the feasibility of using gene therapy to treat chronic traumatic encephalopathy

Radical procedures to treat oral infections are not necessary before stem cell transplantation

Researchers study new immunogenic properties of already existing anti-cancer drugs

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