Cell News and Research

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Space travel can affect intestinal function of astronauts

Bacteria, fungi, and viruses can enter our gut through the food we eat. Fortunately, the epithelial cells that line our intestines serve as a robust barrier to prevent these microorganisms from invading the rest of our bodies.

26 Nov 2019

Researchers win grants to find innovative treatments for debilitating skin diseases

National leaders in research to cure debilitating skin diseases based at the Gates Center for Regenerative Medicine on the University of Colorado Anschutz Medical Campus have won a second NIH grant to further investigations of innovative treatments.

26 Nov 2019

Study points to two types of motion that keeps cells in shape

The health of cells is maintained, in part, by two types of movement of their nucleoli, a team of scientists has found. This dual motion within surrounding fluid, it reports, adds to our understanding of what contributes to healthy cellular function and points to how its disruption could affect human health.

26 Nov 2019

LACV-infected cerebral organoids reveal how to protect neurons from virus-induced death

Scientists have determined that La Crosse virus, which can cause inflammation of the brain, or encephalitis, in children, affects brain cells differently depending on their developmental stage.

26 Nov 2019

Mcl-1 inhibition blocks cell survival in ER+ breast cancers

While estrogen receptor - + breast cancers express high levels of three anti-apoptotic Bcl-2 family members, pharmacological inhibition of Bcl-2 and/or Bcl-xL fails to induce cell death in ER + breast cancer cell lines, due to rapid and robust Mcl-1 upregulation.

26 Nov 2019

Splicing factor enhances ability of triple negative breast cancers to grow and metastasize

If your DNA is a cookbook, a single gene is a recipe. But it's a flexible recipe that if edited one way can make a pie; edited another way can make a cake. And that difference can mean cancer, as a team of researchers who looked at those gene editors writes in the 26 November issue of Cell Reports.

26 Nov 2019

Study shows how fiber spacing could control cell sticking

Researchers from the Mechanobiology Institute at the National University of Singapore have shown that cells can attach to the fibrous protein meshwork that surrounds them only if the fibers are spaced close enough.

26 Nov 2019

Stem cells do not take the day off on national holidays

While most of us are stuffing ourselves with turkey and pumpkin pie at home on Thanksgiving Day, the staff at one Cedars-Sinai laboratory will be on the job, feeding stem cells.

26 Nov 2019

A large library of products derived from fungi could help find new drugs

An enormous library of products derived from more than ten thousand fungi could help us find new drugs.

26 Nov 2019

Broadly expressed metabolic approach could make sarcoma susceptible to targeted therapies

Soft tissue sarcoma cells stop a key metabolic process which allows them to multiply and spread, and so restarting that process could leave these cancers vulnerable to a variety of treatments.

26 Nov 2019

Targeting molecular mechanisms could be beneficial in diabetic wound care

When our skin is damaged, a whole set of biological processes springs into action to heal the wound. Now, researchers from the VIB-UGent Center for Inflammation Research have shown that one of the molecules involved in this, HMGB1, slows down wound healing.

26 Nov 2019

New way to thwart HIV infection at early stages

1.7 million. That's how many people are infected with the human immunodeficiency virus (HIV) each year worldwide. 1.7 million people who are condemned to lifelong antiretroviral therapy (ART) or risk developing fatal AIDS . Out of the 37.9 million people living with HIV (PLWH), 22.3 million have access to ART, allowing them to have an almost normal lifespan.

26 Nov 2019

Key mechanism identified for how antiviral immune responses reprogram liver metabolism

Researchers at the CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences identified a key mechanism for how antiviral immune responses reprogram liver metabolism. Their recent study, which was published in the renowned scientific journal Immunity, investigated the communication between inflammation and liver metabolism during chronic viral infection.

26 Nov 2019

Newly developed personalized vaccine system could delay onset of pancreatic cancer

Researchers from Queen Mary University of London and Zhengzhou University have developed a personalized vaccine system that could ultimately delay the onset of pancreatic cancer. The study provides strong proof-of-concept for the creation of a vaccine for cancer prevention in individuals at high risk of developing this disease and to slow down tumor growth in patients who are affected by it.

26 Nov 2019

Enzyme caspase-8 controls apoptosis, necroptosis and pyroptosis

The enzyme caspase-8 induces a molecular cell death programme called pyroptosis without involving its enzymatic activity, a new study by Hamid Kashkar published in Nature shows.

26 Nov 2019

New method for correcting hypoxic conditions of the central nervous system

Hypoxia is a key factor that accompanies most brain pathologies, including ischemia and neurodegenerative diseases.

26 Nov 2019

Researchers find new way to protect against disease in MS model

Researchers have found a new and unexpected way of preventing disease in a preclinical model of multiple sclerosis (MS).

26 Nov 2019

Studying the genomes of hibernating mammals could improve understanding and treatment of obesity

A discovery about mammalian genomes and hibernation could aid understanding and treatment of obesity and metabolic disorders.

26 Nov 2019

Novoheart collaborates with AstraZeneca to develop world’s first human heart-in-a-jar model of heart failure

Novoheart, a global stem cell biotechnology company, is pleased to announce a collaboration with global biopharmaceutical company AstraZeneca, in an effort to develop the world’s first human-specific in vitro, functional model of heart failure with preserved ejection fraction (HFpEF), a common condition especially among the elderly and in women, with the reported prevalence approaching 10% in women over the age of 80 years.

26 Nov 2019

Tandem radiation therapy effective in prostate cancer patients with no treatment options

Reports of new cancer treatments often raise high hopes and expectations, particularly, of course, among cancer patients and their families.

26 Nov 2019

Cell News and Research

Space travel can affect intestinal function of astronauts

Researchers win grants to find innovative treatments for debilitating skin diseases

Study points to two types of motion that keeps cells in shape

LACV-infected cerebral organoids reveal how to protect neurons from virus-induced death

Mcl-1 inhibition blocks cell survival in ER+ breast cancers

Splicing factor enhances ability of triple negative breast cancers to grow and metastasize

Study shows how fiber spacing could control cell sticking

Stem cells do not take the day off on national holidays

A large library of products derived from fungi could help find new drugs

Broadly expressed metabolic approach could make sarcoma susceptible to targeted therapies

Targeting molecular mechanisms could be beneficial in diabetic wound care

New way to thwart HIV infection at early stages

Key mechanism identified for how antiviral immune responses reprogram liver metabolism

Newly developed personalized vaccine system could delay onset of pancreatic cancer

Enzyme caspase-8 controls apoptosis, necroptosis and pyroptosis

New method for correcting hypoxic conditions of the central nervous system

Researchers find new way to protect against disease in MS model

Studying the genomes of hibernating mammals could improve understanding and treatment of obesity

Novoheart collaborates with AstraZeneca to develop world’s first human heart-in-a-jar model of heart failure

Tandem radiation therapy effective in prostate cancer patients with no treatment options

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