Q Fever News and Research

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Outpatient CAR-T therapy shows promise for treating lymphoma patients

In the largest prospective study to date examining the use of chimeric antigen receptor (CAR)-T therapy in a community setting on an outpatient basis, patients with relapsed or refractory large B-cell lymphoma (LBCL) responded well to treatment with few serious side effects, according to results published today in Blood Advances.

30 Sep 2024

Researchers gain new understanding of how immune cells respond to heat during fever

The study reveals that moderate fever enhances CD4 T cell activity while reducing regulatory T cell suppression, highlighting temperature's immune effects.

25 Sep 2024

Fever enhances immune cell activity and induces mitochondrial stress

Fever temperatures rev up immune cell metabolism, proliferation and activity, but they also - in a particular subset of T cells - cause mitochondrial stress, DNA damage and cell death, Vanderbilt University Medical Center researchers have discovered.

20 Sep 2024

Phase 1 trial shows safety and efficacy of personalized vaccine for lymphoplasmacytic lymphoma

A team of researchers from City of Hope®, one of the largest and most advanced cancer research and treatment organizations in the U.S., and The University of Texas M.D. Anderson Cancer Center, have reported safety and efficacy results from a Phase 1 trial that featured a personalized vaccine to treat lymphoplasmacytic lymphoma, a rare and slow-growing type of blood cancer, according to a study published recently in Nature Communications.

19 Sep 2024

IBD increases type 1 diabetes risk, revealing a bidirectional link between the two conditions

Researchers discovered that IBD significantly increases the risk of developing T1D, and this association works both ways, independent of genetics and familial factors. The strongest link was seen in ulcerative colitis patients.

19 Sep 2024

Study paves way for revolutionizing the management of muscle disorders

The type 1 ryanodine receptor (RyR1) is an important calcium release channel in skeletal muscles essential for muscle contraction.

18 Sep 2024

Newly discovered mechanism could revolutionize infertility care by promoting embryo implantation

A team from Kumamoto University has uncovered a new mechanism that could revolutionize infertility care by promoting embryo implantation.

18 Sep 2024

Survey reveals significant gaps in global pandemic preparedness

Abbott announced the findings of a new survey; among leading infectious disease experts around the world on the state of pandemic preparedness and found that while most agree that preparation has improved since the COVID-19 pandemic, respondents say significant gaps remain in building surveillance programs to identify emerging pathogens, public health funding and having adequate testing infrastructure capabilities.

18 Sep 2024

Early data shows mRNA-4359 may benefit patients with advanced solid cancers

Interim data from the Phase I dose escalation part of the mRNA cancer immunotherapy (mRNA-4359), show promise in patients with advanced solid cancers.

16 Sep 2024

NIH funds new research to combat emerging viruses

Albert Einstein College of Medicine has received a five-year, $14 million per year grant from the National Institute of Allergy and Infectious Diseases (NIAID) to participate in a broad national effort to develop "plug-and-play" vaccines and antibody-based therapies against a wide range of emerging viruses. The grant is part of NIAID's new Research and Development of Vaccines and Monoclonal Antibodies for Pandemic Preparedness (ReVAMPP) Network, which was announced earlier today.

14 Sep 2024

New research network focuses on high-priority viruses

The National Institutes of Health (NIH) has established a pandemic preparedness research network to conduct research on high-priority pathogens most likely to threaten human health with the goal of developing effective vaccines and monoclonal antibodies. Currently, many of the diseases caused by these pathogens have no available vaccines or therapeutics, and investing in this research is key to preparing for potential public health crises - both in the United States and around the world. NIH's National Institute of Allergy and Infectious Diseases (NIAID) expects to commit approximately $100 million per year to fund the program, pending the availability of funds.

14 Sep 2024

Early Phase I data shows promise for mRNA cancer immunotherapy in advanced solid cancers

Interim data from the Phase I dose escalation part of the mRNA cancer immunotherapy (mRNA-4359), show promise in patients with advanced solid cancers.

12 Sep 2024

New vaccine candidate shows promise for protecting against Lassa fever

Researchers from Thomas Jefferson University and the University of Maryland Baltimore, in collaboration with the United States Army Medical Research Institute of Infectious Diseases (USAMRIID) and the Geneva Foundation, have developed a promising new vaccine candidate that protects against Lassa fever.

12 Sep 2024

Severe illness odds higher in COVID-19 vs other illnesses

Study found that COVID-19 cases were more likely to experience severe illness and persistent symptoms compared to non-COVID-19 respiratory illnesses, with age, preexisting conditions, and chronic respiratory disease increasing the risk of post-acute COVID-19 syndrome (PACS).

10 Sep 2024

Insights on diagnosing and treating scabies, bedbugs, and lice effectively

Research in outlines the causes and treatments for scabies, bedbugs, and body lice, stressing the importance of accurate diagnosis and social factors.

10 Sep 2024

Cell-free RNA analysis enhances early detection of pediatric inflammatory conditions

RNA is expelled from cells via cell death or active release, and can then find its way into blood plasma. A Cornell University-led collaboration has developed machine learning models that use these cell-free molecular RNA dregs to diagnose pediatric inflammatory conditions that are difficult to differentiate.

9 Sep 2024

Study links air pollution and limited green spaces to higher respiratory hospitalization risk

Long-term exposure to air pollution and a lack of access to green spaces increases the risk of hospitalization for respiratory conditions, according to a study presented at the European Respiratory Society (ERS) Congress in Vienna, Austria.

9 Sep 2024

Chinese farmed fur animals found to harbor dozens of novel viruses

Researchers identified 125 virus species in Chinese farmed fur animals, including 36 novel viruses with significant zoonotic potential, emphasizing the need for enhanced surveillance to prevent future pandemics.

9 Sep 2024

Long COVID significantly affects children for up to 36 months, vaccines offer crucial protection

Study reveals the significant and lasting impact of long COVID on children, emphasizing the protective role of vaccines and the increased risk of autoimmune disorders.

8 Sep 2024

Mpox inactivated in 60 seconds with Σ-MM™ & patient friendly collection swab

In the wake of the global Mpox outbreak in non-endemic countries in 2022, the medical community has been searching for safer and more efficient ways to transport and test virus samples, especially from patients in areas with limited biological containment facilities.

From Medical Wire 6 Sep 2024

Q Fever News and Research

Outpatient CAR-T therapy shows promise for treating lymphoma patients

Researchers gain new understanding of how immune cells respond to heat during fever

Fever enhances immune cell activity and induces mitochondrial stress

Phase 1 trial shows safety and efficacy of personalized vaccine for lymphoplasmacytic lymphoma

IBD increases type 1 diabetes risk, revealing a bidirectional link between the two conditions

Study paves way for revolutionizing the management of muscle disorders

Newly discovered mechanism could revolutionize infertility care by promoting embryo implantation

Survey reveals significant gaps in global pandemic preparedness

Early data shows mRNA-4359 may benefit patients with advanced solid cancers

NIH funds new research to combat emerging viruses

New research network focuses on high-priority viruses

Early Phase I data shows promise for mRNA cancer immunotherapy in advanced solid cancers

New vaccine candidate shows promise for protecting against Lassa fever

Severe illness odds higher in COVID-19 vs other illnesses

Insights on diagnosing and treating scabies, bedbugs, and lice effectively

Cell-free RNA analysis enhances early detection of pediatric inflammatory conditions

Study links air pollution and limited green spaces to higher respiratory hospitalization risk

Chinese farmed fur animals found to harbor dozens of novel viruses

Long COVID significantly affects children for up to 36 months, vaccines offer crucial protection

Mpox inactivated in 60 seconds with Σ-MM™ & patient friendly collection swab

A New Approach to Preventing Bladder Cancer Recurrence

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

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