Spina Bifida News and Research

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Spina bifida is a neural tube defect that happens in the first month of pregnancy when the spinal column does not close completely. According to the Mayo Clinic, approximately one in every 2,000 children born in the U.S. is diagnosed with spina bifida. Risk factors include the presence of a neural tube defect in a previous child, lack of folic acid, some medications, diabetes and the mother's age. Most patients with spina bifida have neurogenic bladders. Neurogenic bladders function poorly and over time, without correction, can result in kidney damage and ultimately kidney failure.

Folic acid appears to reduce risk of cleft lip and palate

A new study finds that women who take folic acid supplements early in their pregnancy can substantially reduce their baby's chances of being born with a facial cleft.

28 Jan 2007

Impact of birth defects on families and nation

Two separate government reports highlight the economic costs of birth defects, focusing attention on the ongoing need for prevention.

22 Jan 2007

Folic acid shown to prevent heart attacks and stroke

British researchers have found enough scientific evidence to support the claim that folic acid is both an easy and inexpensive way to reduce heart disease and strokes.

27 Nov 2006

UK experts call for debate on euthanasia for seriously disabled newborns

The prestigious Royal College of Obstetricians and Gynaecology in Britain has suggested that there needs to be open debate about the extent that doctors should go to when it comes to ensuring the survival of seriously disabled babies.

6 Nov 2006

Another set of conjoined twins undergo lengthy separation surgery

In what is expected to be a long and lengthy operation, four-month-old conjoined twin boys have embarked on separation surgery in a hospital in Washington.

6 Sep 2006

Researchers discover how genes and diet interact to cause birth defects

Expectant mothers may someday get a personalized menu of foods to eat during pregnancy to complement their genetic makeup as a result of new research at Washington University School of Medicine in St. Louis.

8 Aug 2006

Folic acid may be added to all bread in Britain

The Food Standards Agency in the UK is recommending the addition of the vitamin folic acid to all flour and bread on sale in Britain within the next year.

5 Apr 2006

More women need to know about folic acid's ability to prevent birth defects

Each year in Minnesota, more than 2,000 babies are born with birth defects. Many of those birth defects likely could have been prevented if the mother had taken enough folic acid.

10 Jan 2006

Gene discovery may prevent craniofacial birth defects

Craniofacial researchers have developed an animal model that explains how skull malformations occur and how they might be prevented.

22 Dec 2005

Twins, triplets have greater chance of birth defects

Twins, triplets and other multiples have a nearly 50 percent greater chance of being born with birth defects, and boys tend to be more at risk than girls, according to two population-based studies conducted at the University of Florida.

5 Dec 2005

Eat your way to a better brain for your baby

A team of British scientists at Manchester and Lancaster Universities has turned established thinking on its head in a bid to understand the serious and often deadly condition, hydrocephalus, commonly known as 'water on the brain'.

From The University of Manchester 28 Nov 2005

Tissue engineering used to reconstruct defective tracheas (windpipes) in fetal lambs

Researchers at Children's Hospital Boston report using tissue engineering to reconstruct defective tracheas (windpipes) in fetal lambs, first using cells from the amniotic fluid to grow sections of cartilage tube, and then implanting these living grafts into the lambs while still in the womb.

9 Oct 2005

High blood glucose levels early in pregnancy deprive the embryo of oxygen

The babies of women with diabetes are two to five times more likely to develop birth defects than offspring of women without the disease.

4 Oct 2005

Survey highlights the need to increase folic acid fortification of the grain supply

Only one-third of childbearing age women are taking a multivitamin containing the B vitamin folic acid daily to prevent serious birth defects of the brain and spine in their future babies, according to a decade of March of Dimes surveys.

3 Oct 2005

Folic acid levels should be double to provide maximum protection during pregnancy

Reports say that the U.S. government decision to add folic acid to enriched grain products has reduced the incidence of two devastating birth defects. but more needs to be done.

6 Sep 2005

Folic acid fortification of grain foods has produced a one-third decline in serious birth defects of the brain and spine

...but the March of Dimes urged federal officials to help spare a greater number of babies from these devastating conditions by requiring higher levels of the B vitamin.

6 Sep 2005

Psychological distress of parents of children with spina bifida

Parents of children with spina bifida suffer from more psychological distress than parents of able-bodied children. Research published in the open access journal BMC Pediatrics reveals that having a child with spina bifida (SB) has a negative effect on parents' psychological well-being.

25 Aug 2005

Neural tube defects decrease with folic acid fortification

A new study published online April 21, 2005 in the American Journal of Medical Genetics Part A examines whether the recent decline in neural tube defects in Chile was due to the addition of folic acid to wheat flour in that country or to pre-existing decreasing trends. The journal is available online via Wiley InterScience.

21 Apr 2005

Anticonvulsant drug valproate poses greater birth-defect risk than suspected

Use of the anticonvulsant drug valproate during pregnancy may pose a significantly great risk of birth defects than does use of other antiseizure medications.

22 Mar 2005

Brewing up potential anti-cancer drugs from green tea

Drinking green tea has a protective effect against some forms of cancer but drinking large amounts can increase the risk of birth defects such as spina bifida – according to previous epidemiological studies.

15 Mar 2005