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New data shows zigakibart sustains proteinuria remission and kidney function in IgA nephropathy

New 100-week data from the ongoing Phase 1/2 study of zigakibart, an investigational anti-APRIL monoclonal antibody, reinforce its potential as a disease-modifying treatment for IgA nephropathy (IgAN).

5 Jun 2025

Type 2 diabetes drug shows improvements for patients with progressive liver disease

The sodium glucose cotransporter 2 (SGLT-2) inhibitor drug dapagliflozin, widely used to treat type 2 diabetes, also shows improvements for patients with progressive liver disease, finds a clinical trial from China published by The BMJ today.

5 Jun 2025

AI-designed drug shows early promise for lung fibrosis patients in clinical trial

Researchers report that rentosertib, an AI-discovered TNIK inhibitor, showed promising safety and potential to improve lung function in patients with idiopathic pulmonary fibrosis in a 12-week phase 2a clinical trial. The highest dose group demonstrated a trend toward increased forced vital capacity, especially among patients not receiving standard antifibrotic therapy, supporting further clinical investigation.

4 Jun 2025

Scientists explain how eating a rainbow of foods lowers your risk for chronic illness

Consuming a variety of flavonoid-rich foods can lower all-cause mortality and chronic disease risks, emphasizing the importance of dietary diversity.

4 Jun 2025

Rethinking healthcare through the science of aging

A new editorial was published in Aging (Aging-US) Volume 17, Issue 5, on May 29, 2025, titled "Rethinking healthcare through aging biology."

4 Jun 2025

New screening tool enhances early detection of pulmonary hypertension

A novel screening approach developed by physicians at the Lewis Katz School of Medicine at Temple University shows significant promise for improving the detection of pulmonary arterial hypertension (PAH)-a life-threatening form of heart failure related to high blood pressure in the lung circulation that is often overlooked due to vague symptoms such as fatigue and shortness of breath.

4 Jun 2025

New molecular mechanism offers hope for causal epilepsy treatments

Epilepsy is primarily treated symptomatically - that is, the majority of the available medications aim to suppress seizures without influencing the underlying causes of the disease.

4 Jun 2025

Two blood pressure management strategies yield similar cognitive outcomes after non-cardiac surgery

A large international study has found that two different approaches to managing blood pressure in older adults undergoing non-cardiac surgery, one avoiding low blood pressure (hypotension) and the other high blood pressure (hypertension), lead to similar outcomes in terms of in-hospital delirium and cognitive changes one year after surgery.

4 Jun 2025

Does lithium offer hope for long COVID brain fog and fatigue? New trial gives mixed results

A randomized clinical trial found that low-dose lithium aspartate did not improve cognitive dysfunction or fatigue in long COVID patients. Higher doses showed possible benefits in a small exploratory substudy, but larger trials are needed.

4 Jun 2025

Navigating the dual role of B cells in tumor immunity

B lymphocytes exhibit dual roles in tumorigenesis, acting as both allies and adversaries in the tumor microenvironment (TME).

3 Jun 2025

Scientists develop new system for classifying processed foods

Recent years have seen growing scrutiny and debate around processed foods, but researchers have struggled to pin down what aspects of food processing are most relevant to health.

3 Jun 2025

Maternal obesity linked to children's heightened risk of infection-related hospitalizations

Children born to mothers who are very obese with a BMI of 35 or higher are at heightened risk of being admitted to hospital for an infection, finds a long term study published in the open access journal BMJ Medicine.

3 Jun 2025

Daily bean consumption linked to improved heart and metabolic health

A new study suggests that regularly eating a cup of beans a day may offer measurable benefits for heart and metabolic health.

3 Jun 2025

Eating mangos daily may help reduce cholesterol and blood pressure in postmenopausal women

Each year, 1.3 million women enter menopause-a life stage during which heart disease risk rises significantly.

3 Jun 2025

Aging increases brain vulnerability to mild hypoxia and blood-brain barrier disruption

A new research paper was published in Aging (Aging-US) on May 1, 2025, as the cover of Volume 17, Issue 5, titled "Defining the hypoxic thresholds that trigger blood-brain barrier disruption: the effect of age."

3 Jun 2025

Transforming IBS treatment through psychedelic medicine

In a comprehensive Genomic Press Interview published today, Dr. Erin E. Mauney reveals how her pioneering research brings psychedelic medicine into gastroenterology for the first time, potentially transforming treatment for millions suffering from intractable irritable bowel syndrome (IBS).

3 Jun 2025

Native Americans hurt by federal health cuts, despite RFK Jr.’s promises of protection

Navajo Nation leaders took turns talking with the U.S. government's top health official as they hiked along a sandstone ridge overlooking their rural, high-desert town before the morning sun grew too hot.

3 Jun 2025

Can smoking while pregnant harm your child’s teeth? New research suggests yes

Maternal smoking during pregnancy is associated with dental anomalies in children, including enamel defects and hypodontia, necessitating more rigorous studies.

2 Jun 2025

Multiple chatbots simulate group therapy to help women manage premenstrual syndrome

A research team has designed and implemented a group motivational interviewing system using multiple chatbots to support premenstrual syndrome (PMS), a common disorder among women.

2 Jun 2025

Cannabis use among older adults in the US reaches record levels

Marijuana use among older adults in the US has reached a new high, with 7 percent of adults aged 65 and over who report using it in the past month, according to an analysis led by researchers with the Center for Drug Use and HIV/HCV Research (CDUHR) at the NYU School of Global Public Health.

2 Jun 2025

Chronic News and Research

New data shows zigakibart sustains proteinuria remission and kidney function in IgA nephropathy

Type 2 diabetes drug shows improvements for patients with progressive liver disease

AI-designed drug shows early promise for lung fibrosis patients in clinical trial

Scientists explain how eating a rainbow of foods lowers your risk for chronic illness

Rethinking healthcare through the science of aging

New screening tool enhances early detection of pulmonary hypertension

New molecular mechanism offers hope for causal epilepsy treatments

Two blood pressure management strategies yield similar cognitive outcomes after non-cardiac surgery

Does lithium offer hope for long COVID brain fog and fatigue? New trial gives mixed results

Navigating the dual role of B cells in tumor immunity

Scientists develop new system for classifying processed foods

Maternal obesity linked to children's heightened risk of infection-related hospitalizations

Daily bean consumption linked to improved heart and metabolic health

Eating mangos daily may help reduce cholesterol and blood pressure in postmenopausal women

Aging increases brain vulnerability to mild hypoxia and blood-brain barrier disruption

Transforming IBS treatment through psychedelic medicine

Native Americans hurt by federal health cuts, despite RFK Jr.’s promises of protection

Can smoking while pregnant harm your child’s teeth? New research suggests yes

Multiple chatbots simulate group therapy to help women manage premenstrual syndrome

Cannabis use among older adults in the US reaches record levels

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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