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Study evaluates stem cells' ability to prevent major cause of death in preterm infants

A phase 2 clinical trial whose results were released today in STEM CELLS Translational Medicine might point to a way to overcome bronchopulmonary dysplasia (BPD), a major cause of death in preterm infants.

20 Apr 2021

Scientists receive NIH grant to develop an adjuvant vaccine for opioid use disorder

Opioid addicts wage a daily war within over whether or not to use a drug whose side effect can be death. If those same addicts, however, had the choice to take an opioid vaccine once or twice a year, their internal struggle could be over.

20 Apr 2021

Screening drug candidates for COVID-19 treatment using computational methods

Researchers identified two potential drug candidates that can inhibit SARS-CoV-2 in vitro. Their combination can work synergistically and increase their inhibitory effect.

19 Apr 2021

Plant-derived compound isorhamnetin may have antiviral potential against SARS-CoV-2

The lack of new or repurposed drugs to treat patients with severe or critical COVID-19 has been one of the biggest hurdles to reducing mortality rates in the ongoing pandemic caused by SARS-CoV-2. A new study describes the potential for the use of the plant molecule isorhamnetin in the management of this virus.

19 Apr 2021

SARS-CoV-2 nucleoprotein can trigger α-synuclein amyloid fibril formation

A new study, released as a preprint on the bioRxiv* server, casts some light on the pathogenesis of acute and subacute neurological complications associated with COVID-19.

19 Apr 2021

Three teams selected to receive the first awards from Dartmouth Innovations Accelerator for Cancer

Three teams of Dartmouth researchers have been selected to receive the first awards from the Dartmouth Innovations Accelerator for Cancer.

17 Apr 2021

Curcumin nanosystems could be powerful COVID-19 therapeutics

With new variants of SARS-CoV-2 emerging, the COVID-19 pandemic is far from over. While the global vaccine rollout has moved at an impressive speed, the search for new safe, effective, and targeted therapies is still on. Now, a new study reviews the potential for curcumin, a natural alkaloid derived from turmeric, and nanosystems to treat COVID-19.

16 Apr 2021

New plasmonic isothermal PCR technology can detect respiratory viral pathogens in 30 minutes

Researchers in South Korea developed a plasmonic isothermal recombinase polymerase amplification (RPA) array chip, the world's first plasmoinc isothermal PCR technology which can detect 8 types of pathogens (4 bacteria and 4 viruses) that cause acute respiratory infectious diseases in 30 minutes.

15 Apr 2021

Japanese–European scientists detect novel genetic mitochondrial disorder

The list of known genetic mitochondrial disorders is ever-growing, and ongoing research continues to identify new disorders in this category.

15 Apr 2021

Researchers develop “Nano-Glue” with therapeutic potential against SARS-CoV-2

In a recent study, researchers target the electropositive receptor-binding domain (RBD) on the SARS-CoV-2 spike protein with the abundant β-sheet structure as a novel COVID-19 therapeutic drug design.

15 Apr 2021

Can biomaterials offer novel therapeutic strategies against COVID-19?

A team of scientists reviews the current and potential impact of the biomaterial sciences on the COVID-19 pandemic.

15 Apr 2021

Ovarian follicular function unaffected by SARS-CoV-2 infection or Pfizer vaccine, study finds

A new study by researchers in Jerusalem indicates that while specific antibodies to the virus are present in both serum and ovarian follicles following infection or vaccination, there is no apparent adverse effect on follicular function as a result.

15 Apr 2021

Ebola virus's key protein uses molecular triggers in the human cell to change shape

The human genome contains the instructions to make tens of thousands of proteins. Each protein folds into a precise shape - and biologists are taught that defined shape dictates the protein's destined function.

15 Apr 2021

Biognosys announces strategic agreement with Siemens Healthineers

Biognosys announces today that it has established a strategic agreement with Siemens Healthineers through its clinical laboratory in Berkeley, California.

From Biognosys 14 Apr 2021

A new polymersome-based SARS-CoV-2 nanovaccine elicits robust immunity

As newer vaccines are being developed to combat the ongoing pandemic of coronavirus disease 2019 (COVID-19), targeting the pathogen, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), a new preprint research paper posted to the bioRxiv server describes a new subunit nanovaccine that appears to have robust immunogenicity and neutralizing activity.

14 Apr 2021

Study of antiviral nutraceutical phenolics against SARS-CoV-2 main protease

To address this issue, a team of researchers led by Professor Mohamed El Raey of the National Research Centre, Dokki, Cairo, Egypt, looked at phytopharmaceuticals and nutraceuticals as potential antivirals against SARS-CoV-2.

13 Apr 2021

Researchers find a way to fine-tune the molecular assembly line that creates antibiotics

Researchers from North Carolina State University have found a way to fine-tune the molecular assembly line that creates antibiotics via engineered biosynthesis.

13 Apr 2021

Non-invasive neuromodulation approaches can prevent invasive surgery in Parkinson's patients

From optogenetics to sonogenetics to magnetognetics, scientists around the world are investigating new techniques to treat Parkinson's disease without the need for invasive surgery.

13 Apr 2021

Inhibition of nsp14 methyltransferase as a potential antiviral target for SARS-CoV-2

Beyond vaccination, the broad-spectrum antiviral medication remdesivir has robust clinical evidence and is known as the best antiviral treatment to reduce severe COVID-19 infection in hospitalized patients. Research led by John F.X. Diffley of the Chromosome Replication Laboratory suggests a potential therapeutic target for treatment development is the viral RNA cap methyltransferases, essential for viral protein translation and immune evasion.

13 Apr 2021

New test offers a simpler way to quantify the reservoir of intact viruses in HIV patients

A new test that measures the quantity and quality of inactive HIV viruses in the genes of people living with HIV may eventually give researchers a better idea of what drugs work best at curing the disease.

12 Apr 2021

in vitro News and Research

Study evaluates stem cells' ability to prevent major cause of death in preterm infants

Scientists receive NIH grant to develop an adjuvant vaccine for opioid use disorder

Screening drug candidates for COVID-19 treatment using computational methods

Plant-derived compound isorhamnetin may have antiviral potential against SARS-CoV-2

SARS-CoV-2 nucleoprotein can trigger α-synuclein amyloid fibril formation

Three teams selected to receive the first awards from Dartmouth Innovations Accelerator for Cancer

Curcumin nanosystems could be powerful COVID-19 therapeutics

New plasmonic isothermal PCR technology can detect respiratory viral pathogens in 30 minutes

Japanese–European scientists detect novel genetic mitochondrial disorder

Researchers develop “Nano-Glue” with therapeutic potential against SARS-CoV-2

Can biomaterials offer novel therapeutic strategies against COVID-19?

Ovarian follicular function unaffected by SARS-CoV-2 infection or Pfizer vaccine, study finds

Ebola virus's key protein uses molecular triggers in the human cell to change shape

Biognosys announces strategic agreement with Siemens Healthineers

A new polymersome-based SARS-CoV-2 nanovaccine elicits robust immunity

Study of antiviral nutraceutical phenolics against SARS-CoV-2 main protease

Researchers find a way to fine-tune the molecular assembly line that creates antibiotics

Non-invasive neuromodulation approaches can prevent invasive surgery in Parkinson's patients

Inhibition of nsp14 methyltransferase as a potential antiviral target for SARS-CoV-2

New test offers a simpler way to quantify the reservoir of intact viruses in HIV patients

Human iPSCs: A Full Guide to Advanced in Vitro Models and Applications eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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