Birth Defects News and Research

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New vaccine candidate for Zika virus proves to be effective in mice and monkeys

Researchers at the University of Hawaii medical school have successfully developed a vaccine candidate for the Zika virus, showing that it is effective in protecting both mice and monkeys from the infection.

5 Dec 2018

Researchers generate six antibodies to diagnose and treat Zika virus

Researchers have generated six Zika virus antibodies that could be used to test for and possibly treat a mosquito-borne disease that has infected more than 1.5 million people worldwide.

29 Nov 2018

FDA approves new treatment for AML patients

The U.S. Food and Drug Administration today approved Daurismo (glasdegib) tablets to be used in combination with low-dose cytarabine (LDAC), a type of chemotherapy, for the treatment of newly-diagnosed acute myeloid leukemia (AML) in adults who are 75 years of age or older or who have other chronic health conditions or diseases (comorbidities) that may preclude the use of intensive chemotherapy.

22 Nov 2018

Scientists discover biomarkers for Zika-related birth defects

Scientists at USC have discovered biomarkers for fetal birth defects in the blood of pregnant women infected with Zika.

2 Nov 2018

Scientists engineer antiviral peptide that exploits Achilles' heel of Zika virus

Scientists at Nanyang Technological University, Singapore have engineered an antiviral peptide that exploits the Zika virus at its Achilles' heel - the viral membrane - hence stopping the virus from causing severe infections.

24 Oct 2018

Targeting specific signaling pathway could provide new avenue for treating fetal alcohol syndrome

Fetal alcohol spectrum disorders are an array of conditions that can occur in a person whose mother consumed alcohol during pregnancy. Fetal alcohol syndrome, the most severe of these conditions, often results in physical abnormalities, behavioral development issues and intellectual disabilities.

24 Oct 2018

UK set to fortify flour with folic acid to prevent spine defects among newborns

Public Health Minister Steve Brine added that the move would be discussed with the ministers and is likely to raise folic acid consumption among pregnant mothers.

24 Oct 2018

Researchers find pesticide residues lurking in rural NYS homes

Despite the existence of chemical-free methods to eradicate pests, Americans use more than a billion pounds of pesticides per year.

23 Oct 2018

Study: Children with autism are more likely to be overweight, obese

A new study by researchers at Children's Hospital of Philadelphia (CHOP), the University of Pennsylvania and six other centers reveals that children with developmental delays, including autism spectrum disorder, are up to 50 percent more likely to be overweight or obese compared with the general population.

19 Oct 2018

Purdue researchers develop new chemical process to find better drug 'fits' for patients

When a medication doesn't "fit" the body quite right, the results can be devastating. Such is the case for thalidomide, which was prescribed in the 1950s and 1960s as a sedative or hypnotic, even for pregnant women.

16 Oct 2018

UNC researchers receive NIH award to study maternal-fetal transmission of Zika virus

Researchers at the University of North Carolina at Chapel Hill and collaborators in Nicaragua have been given a five-year, $2.7 million R01 award from the U.S. National Institutes of Health to better understand the epidemiology of Zika virus in pregnancy and the impact the virus has on infant neurodevelopment.

26 Sep 2018

Obese pregnant women can restrict weight gain safely with proper nutrition guidance

Being obese or overweight during pregnancy can result in serious health problems for the mother and child. Obstetricians are often reluctant to recommend restricted weight gain for pregnant women due to safety concerns for the baby and lack of time and tools to safely guide women in their weight control efforts.

24 Sep 2018

Cobalt mining in DR Congo takes a high toll on both creuseurs and environment

In past years, the demand for cobalt has been on the increase due to its many applications. For one thing, the metal is a crucial component of rechargeable lithium-ion batteries for smartphones and electric cars.

20 Sep 2018

TGen and PNOC take part in launch of NIH-supported Kids First Data Resource Portal

As part of a national initiative to solve children's diseases, the Translational Genomics Research Institute and the Pacific Pediatric Neuro-Oncology Consortium are participating in the launch of the Kids First Data Resource Portal, which is supported by the National Institutes of Health .

19 Sep 2018

Researchers use CRISPR screen to reveal new targets in squamous cell carcinomas

A little p63 goes a long way in embryonic development - and flaws in p63 can result in birth defects like cleft palette, fused fingers or even missing limbs.

18 Sep 2018

FDA approves new treatment for people with hairy cell leukemia

AstraZeneca and MedImmune, its global biologics research and development arm, announced today that the US Food and Drug Administration has approved LUMOXITI (moxetumomab pasudotox-tdfk) for the treatment of adult patients with relapsed or refractory hairy cell leukemia who have received at least two prior systemic therapies, including treatment with a purine nucleoside analog.

14 Sep 2018

MAPK pathway mediates normal kidney development, reveals study

The prevalence of kidney diseases is growing rapidly due to an aging population and an increased incidence of diseases like diabetes.

14 Sep 2018

Discovery of key mechanism may lead to more functional skin grafts for burn victims

University of Colorado Boulder researchers have discovered a key mechanism by which skin begins to develop in embryos, shedding light on the genetic roots of birth defects like cleft palate and paving the way for development of more functional skin grafts for burn victims.

14 Sep 2018

Researchers develop rapid, cost-effective method to create human cortical organoids

Writing in the current online issue of the journal Stem Cells and Development, researchers at University of California San Diego School of Medicine describe development of a rapid, cost-effective method to create human cortical organoids directly from primary cells.

7 Sep 2018

Endocrine Society announces winners of prestigious 2019 Laureate Awards

The Endocrine Society today announced it has chosen 13 leading endocrinologists as winners of its prestigious 2019 Laureate Awards, the top honors in the field.

6 Sep 2018

Birth Defects News and Research

New vaccine candidate for Zika virus proves to be effective in mice and monkeys

Researchers generate six antibodies to diagnose and treat Zika virus

FDA approves new treatment for AML patients

Scientists discover biomarkers for Zika-related birth defects

Scientists engineer antiviral peptide that exploits Achilles' heel of Zika virus

Targeting specific signaling pathway could provide new avenue for treating fetal alcohol syndrome

UK set to fortify flour with folic acid to prevent spine defects among newborns

Researchers find pesticide residues lurking in rural NYS homes

Study: Children with autism are more likely to be overweight, obese

Purdue researchers develop new chemical process to find better drug 'fits' for patients

UNC researchers receive NIH award to study maternal-fetal transmission of Zika virus

Obese pregnant women can restrict weight gain safely with proper nutrition guidance

Cobalt mining in DR Congo takes a high toll on both creuseurs and environment

TGen and PNOC take part in launch of NIH-supported Kids First Data Resource Portal

Researchers use CRISPR screen to reveal new targets in squamous cell carcinomas

FDA approves new treatment for people with hairy cell leukemia

MAPK pathway mediates normal kidney development, reveals study

Discovery of key mechanism may lead to more functional skin grafts for burn victims

Researchers develop rapid, cost-effective method to create human cortical organoids

Endocrine Society announces winners of prestigious 2019 Laureate Awards

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