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Researchers identify genetic toolkit to reprogram cells into immune sentinels

An international team led by researchers at Lund University in Sweden has identified the molecular tools needed to reprogram ordinary cells into specialized immune cells.

29 Aug 2025

Disrupting protein quality control slows tumor growth in pediatric rhabdomyosarcoma

A new research paper was published in Volume 16 of Oncotarget on August 29, 2025, titled "In vivo manipulation of the protein homeostasis network in rhabdomyosarcoma."

29 Aug 2025

Predictable music phrases found to regulate blood pressure

A new study has found that blood pressure synchronises to predictable phrase structures in music. Blood pressure was more affected by loudness than tempo and was more strongly influenced by phrase structures that were more predictable.

29 Aug 2025

First clinical trial in cats tests targeted therapy for deadly head and neck cancer

Researchers have reported results from the first-ever clinical trial of a new class of targeted therapy in pet cats with head and neck squamous cell carcinoma (HNSCC)-a cancer which is notoriously deadly and difficult to treat.

28 Aug 2025

Abnormal fusion protein drives childhood brain tumor through condensate formation

A study looking at the biophysical properties of an abnormal protein driving cancer cells is giving scientists new therapeutic clues for how to treat ependymoma, the third most common childhood brain tumor.

27 Aug 2025

New insights into bone remodeling process in orthodontic tooth movement under hypoxia

Sustained hypoxia affects orthodontic tooth movement (OTM) by altering osteoclast and osteoblast differentiation, report researchers from Institute of Science Tokyo, Japan.

25 Aug 2025

How a single gene reshapes pain perception through polyamine signaling

Researchers have identified SLC45A4 as a neuronal polyamine transporter genetically linked to human chronic pain. Loss of this gene in mice disrupts polyamine balance, alters spinal GABA levels, and reduces heat and tonic pain sensitivity.

24 Aug 2025

Next-gen sequencing reveals the regulatory potential of the non-coding genome

The non-coding genome, once dismissed as "junk DNA", is now recognized as a fundamental regulator of gene expression and a key player in understanding complex diseases. Following the landmark achievements of the Human Genome Project (HGP), scientists have increasingly focused on deciphering the non-coding regions of the human genome, which comprise approximately 98% of the genetic material.

23 Aug 2025

SOX2 drives progression and therapy resistance in advanced prostate cancer

Prostate cancer remains a global health challenge, ranking as the second most common malignancy among men.

22 Aug 2025

KFF Health News' 'What the Health?': Happy 60th, Medicare and Medicaid!

On July 30, 1965, President Lyndon B. Johnson signed landmark legislation creating Medicare and Medicaid. Sixty years later, the programs represent a fifth of the federal budget and provide coverage to nearly 1 in 4 Americans.

21 Aug 2025

Researchers gain better understanding of how nerve cells can be protected against ALS

By analyzing millions of messenger RNA molecules (mRNA) during the course of ALS, researchers at Stockholm University, in collaboration with scientists at the Paris Brain Institute and Örebro University, have identified why certain nerve cells are resistant to the disease and what happens in the sensitive nerve cells when they are affected.

19 Aug 2025

Why zinc may be the missing nutrient in childhood asthma care

The role of zinc in childhood asthma is critical; deficiency may worsen symptoms, while supplementation could provide a safe, effective treatment alternative.

19 Aug 2025

Mitochondrial metabolite glutathione plays key role in breast cancer metastasis

The mitochondria may be the powerhouse of the cell, but mounting evidence suggests this organelle is also a driving force behind cancer.

18 Aug 2025

Can turmeric/curcumin help with weight control in diabetes?

Curcumin/turmeric supplements modestly reduced body weight, waist size, fat mass, and hip circumference in people with type 2 diabetes. Benefits were also seen in prediabetic individuals, especially with longer use and high-absorption formulations.

18 Aug 2025

Systems biology identifies sentinel biomarkers bridging ankylosing spondylitis and myocardial infarction

Ankylosing spondylitis (AS) is increasingly recognized as an independent risk factor for premature myocardial infarction (MI), yet the molecular bridge linking chronic axial inflammation to acute coronary events remains poorly mapped.

14 Aug 2025

How circadian biology shapes intestinal regeneration and health

The interplay between the circadian clock, intestinal stem cell niche, and epithelial cell fate is shaping our understanding of how gut homeostasis and cellular regeneration are regulated.

14 Aug 2025

Growing use of AI scribes among New Zealand GPs raises ethical and legal questions

Many New Zealand GPs have taken up the use of AI scribes to transcribe patient notes during consultations despite ongoing challenges with their legal and ethical oversight, data security, patient consent, and the impact on the doctor-patient relationship, a study led by the University of Otago, Wellington – Ōtākou Whakaihu Waka, Pōneke has found.

14 Aug 2025

Vagus nerve modulation can effectively halt the progression of cancer-associated cachexia

The Terasaki Institute for Biomedical Innovation announces a significant advancement in addressing the fight against cancer-associated cachexia (CAC), a life-threatening syndrome responsible for over one-third of cancer-related deaths.

14 Aug 2025

New mouse model reveals key role of osteocytes in osteogenesis imperfecta

Osteogenesis imperfecta (OI) refers to a group of rare genetic bone disorders that results in the formation of fragile bones. In patients with OI, the matrix that makes up the bone has been found to be abnormal, leading to an increased risk of fractures.

13 Aug 2025

mRNA vaccine shows potent efficacy in gastric cancer

Gastric cancer is one of the leading causes of cancer-related mortality worldwide, and peritoneal metastasis, wherein the cancer spreads to the peritoneum or the lining of the abdominal cavity, represents the most common form of recurrence after gastric cancer surgery.

13 Aug 2025

Transcription News and Research

Researchers identify genetic toolkit to reprogram cells into immune sentinels

Disrupting protein quality control slows tumor growth in pediatric rhabdomyosarcoma

Predictable music phrases found to regulate blood pressure

First clinical trial in cats tests targeted therapy for deadly head and neck cancer

Abnormal fusion protein drives childhood brain tumor through condensate formation

New insights into bone remodeling process in orthodontic tooth movement under hypoxia

How a single gene reshapes pain perception through polyamine signaling

Next-gen sequencing reveals the regulatory potential of the non-coding genome

SOX2 drives progression and therapy resistance in advanced prostate cancer

KFF Health News' 'What the Health?': Happy 60th, Medicare and Medicaid!

Researchers gain better understanding of how nerve cells can be protected against ALS

Why zinc may be the missing nutrient in childhood asthma care

Mitochondrial metabolite glutathione plays key role in breast cancer metastasis

Can turmeric/curcumin help with weight control in diabetes?

Systems biology identifies sentinel biomarkers bridging ankylosing spondylitis and myocardial infarction

How circadian biology shapes intestinal regeneration and health

Growing use of AI scribes among New Zealand GPs raises ethical and legal questions

Vagus nerve modulation can effectively halt the progression of cancer-associated cachexia

New mouse model reveals key role of osteocytes in osteogenesis imperfecta

mRNA vaccine shows potent efficacy in gastric cancer

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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