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EPFL researchers uncover how the circadian clock regulates 3D chromatin structure

EPFL biologists and geneticists have uncovered how the circadian clock orchestrates the 24-hour cycle of gene expression by regulating the structure of chromatin, the tightly wound DNA-protein complex of the cell. The work is published in Genes & Development.

28 Mar 2018

Briefing note examines ethical issues in whole genome sequencing of babies

The Nuffield Council on Bioethics has today published a briefing note that examines the ethical issues raised by whole genome sequencing of babies.

28 Mar 2018

Vagus nerve stimulation accelerates motor skill recovery after stroke

Researchers at The University of Texas at Dallas have demonstrated a method to accelerate motor skill recovery after a stroke by helping the brain reorganize itself more quickly.

28 Mar 2018

Previously unknown feature of human anatomy identified

Researchers have identified a previously unknown feature of human anatomy with implications for the function of all organs, most tissues and the mechanisms of most major diseases.

27 Mar 2018

Researchers compare mouse and human blood vessels under ischemic conditions

Peripheral obstructive arterial disease develops when blood vessels narrow due to arteriosclerosis and blood flow in the legs (or rarely the arms) becomes clogged. Intermittent claudication is when blood flow disturbances in a limb causes pain, numbness, or coldness during physical activity.

27 Mar 2018

LSTM researchers show potential of novel antiparasitic drug to combat malaria

Researchers from the Liverpool School of Tropical Medicine have shown the large potential impact of a completely new type of antimalarial drug that kills mosquitoes, as opposed to existing drugs that target the parasite, to reduce the spread of malaria.

27 Mar 2018

Screening strategies could reduce multiple myeloma prevalence, mortality

Multiple myeloma is a rare incurable disease that is diagnosed in more than 30,000 people each year in the United States.

27 Mar 2018

Researchers develop microsensor that enables kidney dialysis to be customized

Researchers from Eindhoven University of Technology have developed a microsensor that makes it possible to directly monitor and adjust the composition of kidney dialysis fluid.

27 Mar 2018

Johns Hopkins researchers make great strides in understanding biology behind pulmonary hypertension

Working with cells that line the innermost layer of the blood vessels, Johns Hopkins investigators say they have made a leap forward in understanding the underlying biology behind pulmonary hypertension, a dangerous type of high blood pressure in lungs that ultimately leads to right heart failure and death.

27 Mar 2018

Childhood friendships may have protective influence on physical health in adulthood

Time spent with friends in childhood is associated with physical health in adulthood, according to data from a multi-decade study of men.

27 Mar 2018

Combination therapy effectively induces tumor cell death and reduces spread of breast cancer

Each day, normal human cell tissues express a protein known as p53 that wages war against potential malignancies. However, between 30 and 40 percent of human breast cancers express a defective (mutant) form of p53 that helps cancer cells proliferate and grow.

27 Mar 2018

Without context or cushion, Do online medical results make sense?

As she herded her two young sons into bed one evening late last December, Laura Devitt flipped through her phone to check on the routine blood tests that had been performed as part of her annual physical. She logged onto the patient portal link on her electronic medical record, scanned the results and felt her stomach clench with fear.

27 Mar 2018

Study finds low hepatitis C virus screening rates among baby boomers

Despite the steady increase of liver cancer incidence in the United States in recent decades, data from 2015 indicates that less than 13 percent of individuals born between 1945 and 1965 are estimated to have undergone screening for hepatitis C virus (HCV).

27 Mar 2018

Tele-monitoring can reduce medical appointments for low-risk pregnancies

When Allison Matthews was pregnant with her first child four years ago, her obstetrics clinic scheduled frequent appointments to make sure everything was proceeding normally.

27 Mar 2018

Antibody sweeps away Alzheimer's plaques in mice

Years before people start showing characteristic symptoms of Alzheimer's disease, sticky plaques begin forming in their brains, damaging nearby cells. For decades, doctors have sought ways to clear out these plaques as a way to prevent or treat the disease.

27 Mar 2018

Glycan biomarker enhances screening for breast cancer patients

People diagnosed with early-stage breast cancer have a five-year survival rate of more than 93 per cent.

26 Mar 2018

Lung transplant drug enters clinical trial after decades of research

In the culmination of decades of research at the University of Virginia Health System, doctors have begun human testing of a drug they hope will one day save many lives among lung transplant recipients.

26 Mar 2018

Researchers develop simple process for 3D bio-fabrication based on bacterial cellulose

Bacterial cellulose (BC) nanofibers are promising building blocks for the development of sustainable materials with the potential to outperform conventional synthetic materials.

26 Mar 2018

Researchers examine blood lead concentrations of Flint children before and after water crisis

Flint children's blood lead levels were nearly three times higher almost a decade before the year of the Flint water crisis, new research shows.

26 Mar 2018

Researchers develop ultrathin endoscope to capture neurons firing deep in the brain

Researchers have developed an endoscope as thin as a human hair that can image the activity of neurons in the brains of living mice. Because it is so thin, the endoscope can reach deep into the brain, giving researchers access to areas that cannot be seen with microscopes or other types of endoscopes.

26 Mar 2018