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Clinical trial shows safety of promising TSRI stroke drug

A preliminary Phase 2 clinical trial has demonstrated that patients with acute ischemic stroke, the most common type of stroke, can safely tolerate high doses of 3K3A-APC, a promising anti-stroke drug invented at The Scripps Research Institute.

20 Feb 2018

Sleep disruptions in menopause correlated with hot flashes and depression

Sleep disruptions are one of the most commonly reported complaints among menopausal women. A new study of middle-aged women found that sleep problems vary across the stages of menopause, yet are consistently correlated with hot flashes and depression.

20 Feb 2018

Researchers discover potential new antimalarial treatment targets

Researchers have discovered crucial new processes that allow malaria parasites to escape red blood cells and infect other cells, offering potential new treatment targets.

20 Feb 2018

Researchers provide safety data for common antiparasitic drug used to treat Chagas disease

Benznidazole is one of the two existing antiparasitic drugs for Chagas' disease treatment. However, it is a poorly tolerated drug and its use to treat chronic disease raises safety concerns. Knowledge about its toxicity profile is scarce and mostly based on post-marketing observational studies.

20 Feb 2018

Gout medication may help improve heart function in adult patients

Researchers at the University of Cincinnati College of Medicine have shown that probenecid, a drug long used to treat gout, may be able to improve heart function in adult patients who experience heart failure.

20 Feb 2018

Tiny 'brains on chips' reveal mechanisms underlying brain's wrinkling process

Being born with a "tabula rasa" - a clean slate - in the case of the brain is something of a curse. Our brains are already wrinkled like walnuts by the time we are born. Babies born without these wrinkles - smooth brain syndrome - suffer from severe developmental deficiencies and their life expectancy is markedly reduced.

20 Feb 2018

Stanford researchers explore how gut bacteria respond to common changes in habitat

Researchers at Stanford University are studying how bacteria living in the gut respond to common changes within their habitat, working with mice.

20 Feb 2018

Blood or marrow transplantation survivors have higher risk of cognitive impairment

Allogeneic blood or marrow transplantation recipients are at a significantly higher risk of cognitive impairment in the years post-transplantation, according to a study published in Journal of Clinical Oncology.

20 Feb 2018

Physical activity could be used as strategy for diabetes prevention

Exercising more reduces the risk of diabetes and could see seven million fewer diabetic patients across mainland China, Hong Kong, and Taiwan, according to new research.

20 Feb 2018

Women with type 1 diabetes not protected against coronary artery disease

Constrictions of the coronary blood vessels is a possible consequence of type 1 diabetes, and one that can eventually lead to myocardial infarction or heart failure.

20 Feb 2018

Scientists explore connection between bad sleep habits and stiff blood vessels

What do bad sleep habits and stiff blood vessels have in common? Nothing good, say scientists exploring what appears to be a direct connection between a circadian clock that isn't working as it should and an enzyme that promotes inflammation working overtime.

20 Feb 2018

Immune history influences person's response to flu vaccine

New research on why the influenza vaccine was only modestly effective in recent years shows that immune history with the flu influences a person's response to the vaccine.

20 Feb 2018

UH Cleveland Medical Center explores novel treatments for uterine fibroids

Uterine fibroids, or uterine myomas, can cause symptoms that include unusually long and heavy menstrual flow, pain, enlarged uterus, pressure on the bladder and rectum, and uncomfortable intercourse.

19 Feb 2018

Autism could be predicted from blood or urine tests soon

Thousands of children are being diagnosed with autism on the basis of tests that are mainly based on the behaviour of the child and his or her responses to the tests and behavioural assessments. In short, there are no blood tests or urine tests that can be used to diagnose autism.

19 Feb 2018

Google AI device could predict a person’s risk of a heart attack

Google researchers along with those from its health technology subsidary Verily Life Sciences, have created a new way with which a person’s heart attack risk may be predicted.

19 Feb 2018

Scientists uncover how newly discovered gene helps grow blood vessels

A new study published today found that a newly discovered gene helps grow blood vessels when it senses inadequate blood flow to tissues.

19 Feb 2018

Scientists identify four viruses that can produce insulin-like hormones

Every cell in your body responds to the hormone insulin, and if that process starts to fail, you get diabetes. In an unexpected finding, scientists at Joslin Diabetes Center have identified four viruses that can produce insulin-like hormones that are active on human cells.

19 Feb 2018

Clinical trial studying type 1 diabetes reaches full enrollment

A clinical trial studying type 1 diabetes has reached full enrollment. The Sanford Project: T-Rex Study, a Phase 2 clinical trial conducted collaboratively by Sanford Health and Caladrius Biosciences, Inc., has completed enrollment of 110 children with type 1 diabetes. The study started with two sites at Sanford Health in Sioux Falls, South Dakota, and Fargo, North Dakota, and expanded to 13 additional sites across the United States.

19 Feb 2018

Experimental treatment improves invisible symptoms of a man with spinal cord injury

An experimental treatment that sends electrical currents through the spinal cord has improved "invisible" yet debilitating side effects for a B.C. man with a spinal cord injury.

19 Feb 2018

Lab-grown cerebellar cells may help explain how ASD develops at molecular level

Increasing evidence has linked autism spectrum disorder with dysfunction of the brain's cerebellum, but the details have been unclear. In a new study, researchers at Boston Children's Hospital used stem cell technology to create cerebellar cells known as Purkinje cells from patients with tuberous sclerosis complex, a genetic syndrome that often includes ASD-like features.

19 Feb 2018