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Disrupting ChIP Assay Technology with New Advancements

The Chromatrap ChIP technology is a bead-free method of performing ChIP. The potential of the technology emerged from our capabilities in manufacturing porous plastic filters for the filtration and separation of biological materials.

From Chromatrap® - Porvair Sciences Ltd 27 Jun 2019

Study finds new cancer driver which is fast, furious and loud

The Fast and the Furious movie franchise meets the Fast N' Loud television series to define an oncogene that drives 35% of prostate cancers.

27 Jun 2019

Dangerous brain parasite invades host cell, maintains steady nutrient supply

A team of researchers has found that a dangerous type of parasite that affects the brain, maintains a stable supply of essential nutrients as it replicates in the host cell. In an unexpected turn of events, the body itself delivers food to the harmful predator.

20 Jun 2019

ChIP-seq kit maximizes chromatin-antibody binding and capture

Optimizing protein orientation for maximum chromatin-antibody binding and capture enables Chromatrap® ChIP-seq kits to offer market leading sensitivity.

From Chromatrap® - Porvair Sciences Ltd 19 Jun 2019

Mutant bacterial receptor could help identify therapeutic compounds that inhibit quorum sensing

Researchers have developed a new mutant version of a receptor used by a bacterial pathogen for a chemical communication process called quorum sensing, according to a study published June 13 in the open-access journal PLOS Pathogens by Bonnie Bassler of Princeton University, and colleagues.

From PLOS ONE 14 Jun 2019

New research identifies cellular adaptive mechanisms during hypoxic conditions

Circadian rhythms are 24 hour cycles that are guided by exposure to alternating periods of day and night. These cycles affect biological activities in a variety of living organisms which are attuned to the circadian clock.

12 Jun 2019

Researchers identify macrophages' pathway to nurture PTEN-deficient glioblastoma

A common genetic deficiency empowers glioblastoma to broadcast a molecular message to the wrong type of immune cell, summoning macrophages that protect and nurture the brain tumor instead of attacking it, researchers at The University of Texas MD Anderson Cancer Center report in Cancer Cell.

11 Jun 2019

Learned avoidance behavior can be inherited for multiple generations, say Princeton researchers

Princeton University researchers have discovered that learned behaviors can be inherited for multiple generations in C. elegans, transmitted from parent to progeny via eggs and sperm cells.

7 Jun 2019

Targeted breast cancer therapy shows 'encouraging' results

Researchers have developed a targeted therapy that may significantly increase the survival of pre-menopausal women with advanced breast cancer

3 Jun 2019

Researchers unveil clues into how breast cancer cells spread around the body

Researchers have unveiled clues into how breast cancer cells spread around the body.

31 May 2019

Cancer researchers discover new functions for common oncogene MYC

Cancer researchers have discovered surprising new functions for a protein called MYC, a powerful oncogene that is estimated to drive the development of almost half a million new cancer cases in the US every year.

30 May 2019

UC Santa Cruz researchers determine structure of a 'master switch' for cell division

Unregulated cell division is a hallmark of cancer, and one of the key proteins involved in controlling cell division is called FoxM1.

29 May 2019

'Eye-in-a-dish' model helps scientists to uncover 'surprising' AMD gene variant

Researchers have discovered a new genetic variant responsible for blood vessel dysregulation in the development of age-related macular degeneration (AMD).

29 May 2019

Genetically eliminating TOX factors improves eradication of solid tumors in CAR T model

A decade ago researchers announced development of a cancer immunotherapy called CAR (for chimeric antigen receptor)-T, in which a patient is re-infused with their own genetically modified T cells equipped to mount a potent anti-tumor attack.

28 May 2019

Researchers discover new function of ribosomes in human cells

Researchers from the Stowers Institute for Medical Research have discovered a new function of ribosomes in human cells that may show the protein-making particle's role in destroying healthy mRNAs, the messages that decode DNA into protein.

26 May 2019

University of Freiburg to receive 25.8 million euros for collaborative research centers

The Deutsche Forschungsgemeinschaft has approved grant applications for two collaborative research centers at the University of Freiburg: one for continued grant funding, and one for initial grant funding.

24 May 2019

Cell scientist receives $1.9 million NIH grant to study muscle regeneration

As people age, their muscle regeneration capacity declines in part because they can no longer make enough muscle stem cells to replace damaged tissue.

24 May 2019

Research sheds new light on the function of frequently mutated cancer protein

New research from The Wistar Institute sheds light on the function of the ARID1A protein, encoded by a gene that is among the most frequently mutated across human cancers.

24 May 2019

Scientists uncover unique set of genes that play a role in muscle cellular gene regulation

York University scientists have uncovered a unique set of genes that play a role in muscle cellular gene expression and differentiation which could lead to new therapeutic targets to prevent the spread of muscle cancer.

23 May 2019

Study explores how exposure to potential triggers can increase risk of type 1 diabetes

A new study has investigated how exposure to certain triggers can increase the risk of type 1 diabetes.

22 May 2019

Transcription News and Research

Disrupting ChIP Assay Technology with New Advancements

Study finds new cancer driver which is fast, furious and loud

Dangerous brain parasite invades host cell, maintains steady nutrient supply

ChIP-seq kit maximizes chromatin-antibody binding and capture

Mutant bacterial receptor could help identify therapeutic compounds that inhibit quorum sensing

New research identifies cellular adaptive mechanisms during hypoxic conditions

Researchers identify macrophages' pathway to nurture PTEN-deficient glioblastoma

Learned avoidance behavior can be inherited for multiple generations, say Princeton researchers

Targeted breast cancer therapy shows 'encouraging' results

Researchers unveil clues into how breast cancer cells spread around the body

Cancer researchers discover new functions for common oncogene MYC

UC Santa Cruz researchers determine structure of a 'master switch' for cell division

'Eye-in-a-dish' model helps scientists to uncover 'surprising' AMD gene variant

Genetically eliminating TOX factors improves eradication of solid tumors in CAR T model

Researchers discover new function of ribosomes in human cells

University of Freiburg to receive 25.8 million euros for collaborative research centers

Cell scientist receives $1.9 million NIH grant to study muscle regeneration

Research sheds new light on the function of frequently mutated cancer protein

Scientists uncover unique set of genes that play a role in muscle cellular gene regulation

Study explores how exposure to potential triggers can increase risk of type 1 diabetes

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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