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New CAR-T cell therapy offers effective option for certain blood cancer patients

Siteman Cancer Center at Barnes-Jewish Hospital and Washington University School of Medicine in St. Louis is one of the first centers nationwide to offer a new immunotherapy that targets certain blood cancers.

19 Oct 2017

Study finds mitochondrial DNA damage in Veterans with Gulf War illness

Researchers say they have found the "first direct biological evidence" of damage in veterans with Gulf War illness to DNA within cellular structures that produce energy in the body.

19 Oct 2017

New study describes how gene-environment interaction leads to congenital heart defects

Infants of mothers with diabetes have a three- to five-fold increased risk of congenital heart defects. Such developmental defects are likely caused by a combination of genetic and environmental factors.

19 Oct 2017

Penn researchers functionally dissect gene variant linked to FTLD

Seven years ago, Penn Medicine researchers showed that mutations in the TMEM106B gene significantly increased a person's risk of frontotemporal lobar degeneration (FTLD), the second most common cause of dementia in those under 65.

19 Oct 2017

High systolic blood pressure increases risk of mitral regurgitation, study reveals

A new study, published by Kazem Rahimi of The George Institute for Global Health at the University of Oxford, UK and colleagues, indicates that high blood pressure increases the risk of mitral regurgitation, a condition where leakage occurs in one of the heart valves.

19 Oct 2017

Yale study finds reduced brain glucose levels in people with obesity, type 2 diabetes

Glucose levels are reduced in the brains of individuals with obesity and type 2 diabetes compared to lean individuals, according to a new Yale study. The finding might explain disordered eating behavior -- and even a higher risk of Alzheimer's disease -- among obese and diabetic individuals, the researchers said.

19 Oct 2017

Migraine attacks may actively protect and repair the brain from oxidative stress

A new perspective article highlights a compelling theory about migraine attacks: that they are an integrated mechanism by which the brain protects and repairs itself. Recent insightful findings and potential ways to use them to help migraine sufferers are published in Headache.

19 Oct 2017

T1DM weakens autonomic reflex that regulates blood pressure during exercise, study finds

A new study finds that late-stage type 1 diabetes mellitus (T1DM) weakens the autonomic reflex that regulates blood pressure during exercise, impairing circulation, nerve function and exercise tolerance. The study is published in the American Journal of Physiology - Heart and Circulatory Physiology.

19 Oct 2017

Heart disease patients could benefit from practicing both yoga and aerobic exercise

Heart disease patients who practice yoga in addition to aerobic exercise saw twice the reduction in blood pressure, body mass index and cholesterol levels when compared to patients who practiced either Indian yoga or aerobic exercise alone, according to research to be presented at the 8th Emirates Cardiac Society Congress in collaboration with the American College of Cardiology Middle East Conference October 19-21, 2017 in Dubai.

19 Oct 2017

Families stop donation of organs from deceased relatives who are registered donors

Hundreds of families across England block the donation of organs from deceased relatives, despite the deceased having chosen to sign the Organ Donation Register.

19 Oct 2017

Brain function does not die immediately after the heart stops finds study

According to new research, people can be aware that they are dead after their heart has stopped beating.

19 Oct 2017

Exercise at high levels increases risk of hardening of the arteries

A study comparing exercise patterns and indicators of heart disease over 25-years, have shown that white men who exercise at high levels were 86% more likely to develop plaques in the coronary arteries than men who exercise at lower levels.

18 Oct 2017

HIV pre-exposure prophylaxis (PrEP) could be cost saving for NHS in long run

For men who have sex with men in the UK, a programme that involved providing pre-exposure prophylaxis (PrEP) treatment for HIV could be cost effective and cost saving finds a new study. The economic evaluation was made by a team led by Valentina Cambiano, of University College London and published in the latest issue of Lancet Infectious Diseases.

18 Oct 2017

Blood transfusions should be gender matched between donor and recipient

An emergency blood transfusion mandates matching of the blood types so that the donor and the recipient are compatible in their blood types. There is no other matching between the blood bag and the recipient – race, ethnicity, religion, gender etc.

18 Oct 2017

TGen project to develop standard operating procedures for single-cell RNA sequencing

The Translational Genomics Research Institute today announced grant support from the Chan Zuckerberg Initiative donor advised fund, an advised fund of the Silicon Valley Community Foundation, that will help revolutionize how researchers identify the genetic source of diseases and how best to treat each patient.

17 Oct 2017

New study shows possibility of battling opioid addiction in primary care

For many of the 2 million Americans addicted to opioids, getting good treatment and getting off prescription painkillers or heroin may seem like a far-off dream.

17 Oct 2017

Two studies set groundwork for new avenues to treat influenza and anthrax poisoning

Two recent studies led by biologists at the University of California San Diego have set the research groundwork for new avenues to treat influenza and anthrax poisoning

17 Oct 2017

Arsenic trioxide could be powerful therapy to extend lives of certain glioblastoma patients

From Sherlock Holmes to Agatha Christie, arsenic is often the poison of choice in popular whodunits. But in ultra-low dosage, and in the right form, this naturally occurring chemical element can be a potent force against cancer.

17 Oct 2017

Study opens door to new approach for curing HIV infections

In findings that open the door to a completely different approach to curing HIV infections, scientists from the Florida campus of The Scripps Research Institute have for the first time shown that a novel compound effectively suppresses production of the virus in chronically infected cells, and prevents viral rebound, even when those infected cells are subjected to vigorous stimulation.

17 Oct 2017

Synthetic compound targets enzyme that supports survival and dissemination of metastatic cells

Cancer can most often be successfully treated when confined to one organ. But a greater challenge lies in treating cancer that has metastasized, or spread, from the primary tumor throughout the patient's body.

17 Oct 2017

Blood News and Research

New CAR-T cell therapy offers effective option for certain blood cancer patients

Study finds mitochondrial DNA damage in Veterans with Gulf War illness

New study describes how gene-environment interaction leads to congenital heart defects

Penn researchers functionally dissect gene variant linked to FTLD

High systolic blood pressure increases risk of mitral regurgitation, study reveals

Yale study finds reduced brain glucose levels in people with obesity, type 2 diabetes

Migraine attacks may actively protect and repair the brain from oxidative stress

T1DM weakens autonomic reflex that regulates blood pressure during exercise, study finds

Heart disease patients could benefit from practicing both yoga and aerobic exercise

Families stop donation of organs from deceased relatives who are registered donors

Brain function does not die immediately after the heart stops finds study

Exercise at high levels increases risk of hardening of the arteries

HIV pre-exposure prophylaxis (PrEP) could be cost saving for NHS in long run

Blood transfusions should be gender matched between donor and recipient

TGen project to develop standard operating procedures for single-cell RNA sequencing

New study shows possibility of battling opioid addiction in primary care

Two studies set groundwork for new avenues to treat influenza and anthrax poisoning

Arsenic trioxide could be powerful therapy to extend lives of certain glioblastoma patients

Study opens door to new approach for curing HIV infections

Synthetic compound targets enzyme that supports survival and dissemination of metastatic cells

Improving healthcare sustainability through carbon data

A New Approach to Preventing Bladder Cancer Recurrence

Bringing real-time analytics to downstream bioprocess monitoring

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