Severe Acute Respiratory News and Research

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Study characterizes SARS-CoV-2 Omicron BA.2.86: New variant under watch

Researchers identify a new SARS-CoV-2 variant, BA.2.86, with enhanced ability to evade immunity but lower infectivity compared to current variants. The study highlights the need for global monitoring due to its potential to become a predominant strain if it gains infectivity through mutations.

6 Sep 2023

Review identifies future research directions for the study of a SARS-CoV-2 reservoir in PASC

Researchers reviewed the evidence for SARS-CoV-2 reservoir in post-acute sequelae of COVID-19 (PASC).

6 Sep 2023

Researchers characterize new SARS-CoV-2 BA.2.86 variant neutralization by monoclonal antibodies

Researchers used a SARS-CoV-2 spike protein-pseudotyped viral model to characterize BA.2.86 variant neutralization by monoclonal antibodies.

6 Sep 2023

Early viral exposure in mice weakens vaccine response, raising questions for human studies

Researchers at Washington University have demonstrated that early life exposure to multiple viruses in house mice dampens the immune response to SARS-CoV-2 vaccinations later in life. The study raises concerns about the applicability of common mouse models in immunological research, suggesting that prior pathogen exposure could be a significant variable in predicting vaccine efficacy.

5 Sep 2023

Monovalent vaccine outperforms bivalent in fighting new Omicron variants

New U.S. study finds mRNA-1273.815, a monovalent vaccine targeting the Omicron XBB.1.5 variant, generates higher neutralizing antibody titers compared to its bivalent counterpart. The study supports updating to an XBB.1.5-based monovalent vaccine for the 2023-24 campaign to combat emerging variants.

5 Sep 2023

Novavax's updated XBB.1.5 vaccine shows promising cross-neutralizing antibodies against new COVID-19 variants

The study reveals that Novavax's updated XBB.1.5 vaccine effectively induces cross-neutralizing antibodies against multiple Omicron XBB sub-variants in both mice and non-human primates.

5 Sep 2023

Can SARS-CoV-2 infect poultry?

New research in the Virology Journal suggests that chickens could become intermediate hosts for newly emerged SARS-CoV-2 variants, posing a potential threat to public health. The study identifies AXL and ACE2 receptors in chickens as likely binding sites for the virus, highlighting the need for further research and preventive measures.

5 Sep 2023

COVID-19 hits American Indian and Alaska Native populations hardest, new study reveals

A recent study at the University of New Mexico Hospital highlights that American Indian and Alaska Native populations face disproportionate severity and mortality rates from COVID-19. The research points to the urgent need for targeted interventions and resources to address these health disparities.

5 Sep 2023

How SARS-CoV-2 hijacks Fragile X proteins to fuel infection: New clues in COVID-19 and genetic disorders

Study explores the interaction between SARS-CoV-2's non-structural protein 3 (NSP3) and proteins related to Fragile X mental retardation (FMRPs), shedding light on COVID-19 pathophysiology. The research suggests that the virus exploits these host cell proteins for effective infection and possibly interferes with antiviral defense mechanisms, offering new insights into the genetic basis of Fragile X syndrome.

5 Sep 2023

SARS-CoV-2 Eris variant spreads faster and dodges immunity

Study investigates the characteristics of the EG.5.1 "Eris" variant of SARS-CoV-2, finding it more transmissible among hamsters and slightly better at evading immunity compared to the XBB.1.5 variant. The results suggest that these properties could be driving the variant's increasing prevalence in human populations.

5 Sep 2023

Pandemic pounds: Study reveals COVID-19's impact on pregnancy weight gain patterns

The study reveals that gestational weight gain (GWG) increased during the peak of the COVID-19 pandemic and plateaued in the later stages, affecting especially those who were overweight or obese. It highlights the influence of the pandemic on pregnancy-related outcomes, including pre-pregnancy weight and GWG.

4 Sep 2023

Study characterizes SARS-CoV-2 subvariants to inform development of next-generation COVID-19 vaccines

Researchers characterized two novel SARS-CoV-2 XBB variants, EG.5.1 and XBB.2.3.

4 Sep 2023

Study investigates the pathophysiological mechanisms of PASC after COVID-19

Researchers investigated early pathophysiological mechanisms potentially underlying PASC post-SARS-CoV-2 infection.

4 Sep 2023

Study explores the biology of post-COVID-19 cognitive deficits

Researchers explored the biology of cognitive deficits following acute COVID-19.

4 Sep 2023

Did COVID-19 mortality differ between patients with cancer and the general US population depending on which SARS-CoV-2 variant was dominant?

Researchers comparatively evaluated COVID-19 mortality among cancer patients during different periods of the SARS-CoV-2 outbreak.

4 Sep 2023

Intensive fasting boosts red blood cells' immune powers against COVID-19, study finds

Researchers found that short-term intensive fasting enhances the immune function of red blood cells, including their ability to combat SARS-CoV-2, without affecting their oxygen-carrying capacity. The study reveals that this fasting regimen popular in Asia could offer a multifaceted benefit by amplifying the body's defenses without compromising essential functions.

4 Sep 2023

Biomarkers unveil insights into post-COVID-19 syndrome variability

Researchers studied a prospective observation cohort of patients with post-coronavirus disease 2019 syndrome.

1 Sep 2023

Boosters slow antibody waning but hit a ceiling: Long-term COVID study reveals limits of immunity

The study tracks the long-term kinetics of antibody responses to SARS-CoV-2 after vaccination and infections in New York healthcare workers from 2020 to 2023. It reveals that antibody waning is slower after booster shots, but there's an upper limit to antibody levels, which gradually lowers with repeated SARS-CoV-2 exposures and vaccinations.

31 Aug 2023

Is the rapid evolution of SARS-CoV-2 in white-tailed deer complicating our fight against the pandemic?

New study reveals rapid evolution of SARS-CoV-2 in Ohio's white-tailed deer population, with a 25% seroprevalence rate. The findings suggest a significant risk of animal-to-human transmission and indicate the virus evolves faster in deer than in humans.

31 Aug 2023

Cracking the code on post-vaccine COVID protection

The study investigates the relationship between antibody levels and behavioral factors in 176 adults vaccinated with Pfizer's BNT162b2, finding that higher levels of specific antibodies correlate with greater protection against symptomatic COVID-19. It also suggests that current commercial assays may need reformatting for better risk prediction.

31 Aug 2023

Severe Acute Respiratory News and Research

Study characterizes SARS-CoV-2 Omicron BA.2.86: New variant under watch

Review identifies future research directions for the study of a SARS-CoV-2 reservoir in PASC

Researchers characterize new SARS-CoV-2 BA.2.86 variant neutralization by monoclonal antibodies

Early viral exposure in mice weakens vaccine response, raising questions for human studies

Monovalent vaccine outperforms bivalent in fighting new Omicron variants

Novavax's updated XBB.1.5 vaccine shows promising cross-neutralizing antibodies against new COVID-19 variants

Can SARS-CoV-2 infect poultry?

COVID-19 hits American Indian and Alaska Native populations hardest, new study reveals

How SARS-CoV-2 hijacks Fragile X proteins to fuel infection: New clues in COVID-19 and genetic disorders

SARS-CoV-2 Eris variant spreads faster and dodges immunity

Pandemic pounds: Study reveals COVID-19's impact on pregnancy weight gain patterns

Study characterizes SARS-CoV-2 subvariants to inform development of next-generation COVID-19 vaccines

Study investigates the pathophysiological mechanisms of PASC after COVID-19

Study explores the biology of post-COVID-19 cognitive deficits

Did COVID-19 mortality differ between patients with cancer and the general US population depending on which SARS-CoV-2 variant was dominant?

Intensive fasting boosts red blood cells' immune powers against COVID-19, study finds

Biomarkers unveil insights into post-COVID-19 syndrome variability

Boosters slow antibody waning but hit a ceiling: Long-term COVID study reveals limits of immunity

Is the rapid evolution of SARS-CoV-2 in white-tailed deer complicating our fight against the pandemic?

Cracking the code on post-vaccine COVID protection

Revolutionizing Life Science: An Interview with SCIEX on ASMS, the SCIEX 7500+ System, and AI-Driven Quantitation

From Discovery Biology to ELRIG Chair

Breathing New Life into Diagnostics: Plasmion's SICRIT Technology

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