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Older adults from disadvantaged communities less likely to attend cardiac rehabilitation after heart procedures

Older adults who live in disadvantaged communities are less likely to attend cardiac rehabilitation after common heart procedures, a Michigan Medicine-led study finds.

24 Oct 2023

Blood test detects cancer earlier in individuals with Li-Fraumeni syndrome

Researchers from The Hospital for Sick Children (SickKids), the Ontario Institute for Cancer Research (OICR) and University Health Network (UHN) have demonstrated that by analyzing patients' blood samples, they are able to detect cancer earlier in individuals with Li-Fraumeni syndrome, an inherited condition with an almost 100 percent life-time risk of developing cancer.

24 Oct 2023

Warm-ups may improve muscle performance by exploiting temperature sensitivity

Everybody knows the importance of warming up your muscles before a workout. But what is actually going on when we warm our muscles up, and are all muscles the same? You might be surprised to find out that the science behind this routine activity hasn't always been clear.

24 Oct 2023

Plant microorganisms from fruit and vegetables boost gut diversity

Bacterial diversity in the gut plays an important role in human health. The crucial question, however, is where are the sources of this diversity? It is known that an important part of the maternal microbiome is transferred to the baby at birth, and the same happens during the breastfeeding period via breast milk.

24 Oct 2023

Toxicant released from sugarcane ash may be causing mysterious kidney disease in agricultural workers

The burning of sugarcane and rice husks may be releasing a toxicant causing a mysterious kidney disease in agricultural workers, according to a paper out today in the American Journal of Kidney Diseases.

24 Oct 2023

Biofilm probiotic effective in preventing necrotizing enterocolitis in piglet model

Necrotizing enterocolitis (NEC) is a debilitating and deadly condition that affects infants who were born preterm.

24 Oct 2023

HIF-2α inhibitor belzutifan significantly reduces progression of clear cell renal cell carcinoma

Belzutifan significantly reduced the risk of progression of clear cell renal cell carcinoma (ccRCC), the most common type of kidney cancer, in patients previously treated with immune checkpoint inhibitors and anti-angiogenic therapies compared with everolimus in a phase 3 clinical trial.

24 Oct 2023

Study identifies predictors of opioid overdose after prescription for chronic pain

A large study published in CMAJ (Canadian Medical Association Journal) https://www.cmaj.ca/lookup/doi/10.1503/cmaj.230459 identified 10 predictors of opioid overdose after prescription for chronic pain, which can help clinicians engage in shared decision-making with patients around opioid prescribing.

24 Oct 2023

Diabetes complications linked to increased risk of colorectal cancer recurrence and death

Complications of diabetes can have numerous negative health effects, from impaired vision and nerve damage to kidney dysfunction and heart disease. In an analysis of information on adults with colorectal cancer, patients who also had diabetes - particularly those with diabetic complications - faced a higher risk of dying early.

24 Oct 2023

Perioperative durvalumab may change standard-of-care for patients with resectable lung cancer

A regimen of pre-surgical immunotherapy and chemotherapy followed by post-surgical immunotherapy significantly improved event-free survival (EFS) and pathologic complete response (pCR) rates compared to chemotherapy alone for patients with operable non-small cell lung cancer (NSCLC), according to results of a Phase III trial reported by researchers at The University of Texas MD Anderson Cancer Center.

24 Oct 2023

New research aims to understand the ecology of SARS-CoV-2 at the human-animal interface

At the height of the COVID-19 pandemic, Virginia Tech disease ecologists wondered if the virus was having the same effect on wildlife.

24 Oct 2023

New consortium to build on breakthroughs in malaria research to develop P. vivax vaccines

Plasmodium vivax is the most widespread human malaria-causing pathogen with 2.5 billion people living at risk in Africa, South America, Oceania, and Asia.

24 Oct 2023

AI-assisted smartphone app performs well in skin cancer diagnosis

Artificial intelligence (AI) is already widely used in medical diagnostics. An Austrian-Australian research team led by dermatologist Harald Kittler from MedUni Vienna investigated the extent to which diagnosis and therapy of pigmented skin lesions benefit from it in a realistic clinical scenario.

24 Oct 2023

Finding and targeting dormant tumor cells to prevent breast cancer recurrence

While breast cancer survival continues to improve, thanks to advances in detection and treatment, when breast cancer recurs – or returns after initial treatment – it is incurable.

24 Oct 2023

Research suggests shorter isolation periods for children with COVID-19

School policies that require students with COVID-19 to stay out of the classroom for five days are more than sufficient.

24 Oct 2023

Researchers discover new way to trigger programmed cell death in cancer cells

A research team from the UC Davis Comprehensive Cancer Center has identified a crucial epitope (a protein section that can activate the larger protein) on the CD95 receptor that can cause cells to die.

24 Oct 2023

Study reveals unexpected role of pulmonary ionocytes in lung function

A new study by University of Iowa researchers finds that rare lung cells known as pulmonary ionocytes facilitate the absorption of water and salt from the airway surface.

24 Oct 2023

New insights into the molecular basis of schizophrenia during early brain development

Schizophrenia is a severe neuropsychiatric disease that remains poorly understood and treated.

24 Oct 2023

Neoadjuvant pembrolizumab achieves major pathologic response in more than half of patients with resectable melanoma

In exploratory analyses of results from the SWOG S1801 trial in patients with stage III-IV resectable melanoma, researchers saw a major pathologic response in more than half of surgical specimens taken from patients who had been treated with neoadjuvant (pre-operative) pembrolizumab.

24 Oct 2023

Study sheds light on role of gut fungi in severe COVID-19 and long COVID

Certain gut-dwelling fungi flourish in severe cases of COVID-19, amplifying the excessive inflammation that drives this disease while also causing long-lasting changes in the immune system, according to a new study led by investigators at Weill Cornell Medicine and NewYork-Presbyterian.

24 Oct 2023

Research News and Research

Older adults from disadvantaged communities less likely to attend cardiac rehabilitation after heart procedures

Blood test detects cancer earlier in individuals with Li-Fraumeni syndrome

Warm-ups may improve muscle performance by exploiting temperature sensitivity

Plant microorganisms from fruit and vegetables boost gut diversity

Toxicant released from sugarcane ash may be causing mysterious kidney disease in agricultural workers

Biofilm probiotic effective in preventing necrotizing enterocolitis in piglet model

HIF-2α inhibitor belzutifan significantly reduces progression of clear cell renal cell carcinoma

Study identifies predictors of opioid overdose after prescription for chronic pain

Diabetes complications linked to increased risk of colorectal cancer recurrence and death

Perioperative durvalumab may change standard-of-care for patients with resectable lung cancer

New research aims to understand the ecology of SARS-CoV-2 at the human-animal interface

New consortium to build on breakthroughs in malaria research to develop P. vivax vaccines

AI-assisted smartphone app performs well in skin cancer diagnosis

Finding and targeting dormant tumor cells to prevent breast cancer recurrence

Research suggests shorter isolation periods for children with COVID-19

Researchers discover new way to trigger programmed cell death in cancer cells

Study reveals unexpected role of pulmonary ionocytes in lung function

New insights into the molecular basis of schizophrenia during early brain development

Neoadjuvant pembrolizumab achieves major pathologic response in more than half of patients with resectable melanoma

Study sheds light on role of gut fungi in severe COVID-19 and long COVID

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