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Study reveals mechanism behind failed remyelination in MS

Researchers have discovered that in adult stem cells, the activation of a specific transcription factor induces pathological quiescence and that this is deactivated in MS.

18 Dec 2018

New robust method for microscopically profiling tiny single cells

Many of the cell types in our bodies work in obscure ways, that science does not yet fully understand. That also goes for immune cells, which are vital for protecting us against serious diseases.

17 Dec 2018

Researchers reveal how key transcription factor keeps the immune system in check

Our immune systems defend our bodies against dangerous invaders and help clean up when damage is done. But if our bold protectors are left unsupervised, they sometimes do their jobs too well and end up harming healthy tissues.

17 Dec 2018

Study finds epigenetic differences in the brains of individuals with schizophrenia

A study using a PET scan tracer developed at the Martinos Center for Biomedical Imaging at Massachusetts General Hospital has identified, for the first time, epigenetic differences between the brains of individuals with schizophrenia and those of unaffected study participants.

17 Dec 2018

New research lays out potential path for treatment of Huntington’s disease

New research gives scientists a clearer picture of what is happening in the brains of people with Huntington's disease and lays out a potential path for treatment.

14 Dec 2018

New mouse model shows potential for rapid identification of promising muscular dystrophy therapies

A Massachusetts General Hospital research team has created a new mouse model of a common form of muscular dystrophy with the potential of rapidly distinguishing promising therapeutic drugs from those unlikely to be successful.

13 Dec 2018

Researchers explore how glial cells develop in the brain from neural precursor cells

Two types of cells are active in the brain: nerve cells and glial cells. The latter have long been regarded primarily as supportive cells, but it is increasingly recognized that they play an active role in the communication between neurons in the brain.

10 Dec 2018

New way of controlling HIV latency to completely eradicate the virus

A new study suggests that a genetic switch that causes latent HIV inside cells to begin to replicate can be manipulated to completely eradicate the virus from the human body. Cells harboring latent HIV are "invisible" to the natural defenses of the immune system.

7 Dec 2018

UCR postdoctoral researcher wins prestigious NIH fellowship to study neural crest cells

Rebekah Charney, a postdoctoral researcher in the School of Medicine at the University of California, Riverside, has been awarded the prestigious Ruth L. Kirschstein National Research Service Award Individual Postdoctoral Fellowship by the National Institute of Dental and Craniofacial Research of the National Institutes of Health.

6 Dec 2018

Protecting powerhouse of cells could provide better way to treat acute kidney injury

For the first time, scientists have described the body's natural mechanism for temporarily protecting the powerhouses of kidney cells when injury or disease means they aren't getting enough blood or oxygen.

6 Dec 2018

New therapeutic strategy is emerging for type 2 diabetes

Diabetes is a disease in which blood sugar levels are high over a prolonged period (hyperglycemia). In the case of type 2 diabetes, this phenomenon which is caused by a disruption of the glucose metabolism develops progressively and insidiously.

6 Dec 2018

Researchers succeed in converting human skin cells into blood stem cells

Researchers have succeeded in converting human skin cells into blood stem cells in an international collaboration project.

5 Dec 2018

New approach turns B cells into factories that secrete sacs containing microRNAs

Cancer immunotherapy -- efforts to better arm a patient's own immune system to attack tumors -- has shown great potential for treating some cancers. Yet immunotherapy doesn't work for everyone, and some types of treatment can cause serious side effects.

5 Dec 2018

Researcher discovers key differences in protein production between healthy cells and tumors

The human body is made up of more than 200 types of cell, from bone and brain to liver and lung. Each cell type is determined by the particular combination of proteins it produces.

4 Dec 2018

Novel DNA nanoplatform delivers anticancer agents to multidrug-resistant tumors

One of the most successful techniques to combat multidrug resistance in cancer cells is the downregulation of those genes responsible for drug resistance.

22 Nov 2018

Check your medical records for dangerous errors

When Liz Tidyman's elderly parents moved across the country to be closer to their children and grandchildren years ago, they carried their medical records with them in a couple of brown cardboard folders tied with string.

21 Nov 2018

Scientists use cryo-EM to capture freeze-frames of molecule’s 'lock-and-load' on DNA

Pushing the limits of cryo-electron microscopy, University of California, Berkeley, scientists have captured freeze-frames of the changing shape of a huge molecule, one of the body's key molecular machines, as it locks onto DNA and loads the machinery for reading the genetic code.

20 Nov 2018

Transcription News and Research

Study reveals mechanism behind failed remyelination in MS

New robust method for microscopically profiling tiny single cells

Researchers reveal how key transcription factor keeps the immune system in check

Study finds epigenetic differences in the brains of individuals with schizophrenia

New research lays out potential path for treatment of Huntington’s disease

New mouse model shows potential for rapid identification of promising muscular dystrophy therapies

Researchers explore how glial cells develop in the brain from neural precursor cells

New way of controlling HIV latency to completely eradicate the virus

UCR postdoctoral researcher wins prestigious NIH fellowship to study neural crest cells

Protecting powerhouse of cells could provide better way to treat acute kidney injury

New therapeutic strategy is emerging for type 2 diabetes

Researchers succeed in converting human skin cells into blood stem cells

New approach turns B cells into factories that secrete sacs containing microRNAs

Researcher discovers key differences in protein production between healthy cells and tumors

Novel DNA nanoplatform delivers anticancer agents to multidrug-resistant tumors

Check your medical records for dangerous errors

Scientists use cryo-EM to capture freeze-frames of molecule’s 'lock-and-load' on DNA

Researchers identify multisystem disorder caused by bi-allelic variants in CCDC47 gene

Towards finding a druggable cancer target

Researchers develop novel mouse model to study immunomodulatory therapies

Industry Focus eBook - Cell biology (5th edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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