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New insight into ulcerative colitis

Social, environmental and dietary changes are associated with the changes of disease spectrum in a country. Ulcerative colitis has become a commonly seen disease in China, probably due to extensive consumption of Western foods in recent years.

14 Nov 2007

Anti-inflammation molecule helps fight MS-like disease

An immune system messenger molecule that normally helps quiet inflammation could be an effective tool against multiple sclerosis (MS). Neurology researchers led by Abdolmohamad Rostami, M.D., Ph.D., professor and chair of the Department of Neurology at Jefferson Medical College of Thomas Jefferson University and the Jefferson Hospital for Neuroscience in Philadelphia, have found that the protein interkeukin-27 (IL-27) helped block the onset or reverse symptoms in animals with an MS-like disease.

13 Nov 2007

High-fat diet makes mice susceptible to liver injury

A high fat diet may kill regulatory T cells in the liver, allowing steatosis (simple fatty liver) to develop into steatohepatitis (fatty liver with inflammation), according to the results of a new study in the November issue of Hepatology, a journal published by John Wiley & Sons on behalf of the American Association for the Study of Liver Diseases (AASLD).

2 Nov 2007

Breastfed babies breathe better, except when mother is asthmatic

When it comes to feeding babies, the old adage "breast is best" certainly holds true, with breastfed babies having less diarrhea and fewer ear infections and incidents of wheezing in early life.

2 Nov 2007

Children would need different medical care in wake of dirty bomb

If terrorists were to attack with a dirty bomb, medical authorities should be prepared to treat children differently than adults because their developing bodies would absorb and respond to the radiation exposure in distinct ways, according to a new study from the University of Rochester Medical Center.

31 Oct 2007

Severely restricting calories leads to a longer life

New research now has shown for the first time that such a diet also can maintain physical fitness into advanced age, slowing the seemingly inevitable progression to physical disability and loss of independence.

24 Oct 2007

Stanford seeks volunteers for flu vaccine study

Researchers at the Stanford University School of Medicine and Lucile Packard Children's Hospital are looking for adults and children to participate in three studies that will help them better understand how the flu vaccine works in people of different ages.

22 Oct 2007

Severely restricting calories leads to a longer life

22 Oct 2007

Stem cells guilty of spreading cancer

Scientists in the United States have found that stem cells which are normally associated with potential cures and treatments can also promote the spread of cancer.

3 Oct 2007

How H5N1 virus works

H5N1 influenza, also known as avian influenza, is considered a major global threat to human health, with high fatality rates.

27 Sep 2007

C-reactive protein shown to be a potential target for cancer treatment

Scientists report that a protein best known as a common marker of inflammation plays a key role in the progression of human cancer.

11 Sep 2007

IDM Pharma receives not approvable letter for Mifamurtide for treatment of osteosarcoma

IDM Pharma, Inc. ( NASDAQ:IDMI ) announced today that it received a not approvable letter from the U.S. Food and Drug Administration (FDA) after completing the review of the new drug application (NDA) for the investigational drug mifamurtide (L-MTP-PE), formerly known as Junovan, for the treatment of non-metastatic osteosarcoma, a rare and often fatal bone tumor that typically affects children and young adults.

28 Aug 2007

New way to predict how cells will respond to targeted drug therapies

Models based on this approach could help doctors make better treatment choices for individual patients, who often respond differently to the same drug, and could help drug developers identify the ideal compounds on which to focus their research.

1 Aug 2007

IDM Pharma plans to amend NDA for Mifamurtide (L-MTP-PE) for the treatment of osteosarcoma

IDM Pharma, Inc. has announced that it has recently met with the U.S. Food and Drug Administration (FDA) and informed the FDA that the Company intends to take immediate action to supplement the data in its current New Drug Application (NDA) for mifamurtide (L-MTP-PE), formerly known as Junovan, which is being reviewed for the treatment of children and adolescents with non-metastatic osteosarcoma.

23 Jul 2007

Interleukin-6 - new target in the battle against Ras-induced cancers

In an upcoming Genes & Development paper, Dr. Christopher Counter and colleagues at the Duke University Medical Center have identified IL6 as a new target in the battle against Ras-induced cancers.

16 Jul 2007

New genomics-based technology

Bruce S. Gillis, M.D., M.P.H., a medical toxicologist and CEO of the research group, The Cytokine Institute, will present a tutorial on a new genomics-based technology, msds1(TM).

16 Jul 2007

Why males show a higher rate of inflammation than females in the same diseases

Production of a protein that promotes inflammation appears to be linked to the higher incidence of liver cancer in men than in women, researchers at the University of California, San Diego (UCSD) School of Medicine have determined in mouse studies.

9 Jul 2007

Chronic methamphetamine abuse linked to cardiovascular disease

The study is being published the week of June 25 in an advanced online edition of the Proceedings of the National Academy of Sciences.

26 Jun 2007

Scientists show protein accelerates breast cancer progression in animal models

The study is being published in an advanced online edition of the Proceedings of the National Academy of Sciences.

23 Jun 2007

Results of Tocilizumab study

Nearly half (43.9%) of rheumatoid arthritis (RA) patients receiving tocilizumab 8mg/kg, in addition to ongoing methotrexate therapy experienced a 50% (ACR50) improvement in symptoms at 24 weeks and more than one fifth achieved a 70% symptom improvement, according to results of a study presented at EULAR 2007, the Annual European Congress of Rheumatology in Barcelona, Spain.

19 Jun 2007