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Finding treatments for rare diseases: an interview with Dr Richard Thompson

It is estimated that around 400 rare diseases have licenced treatments, and a large proportion of these are a consequence of orphan drug legislation, which has helped to incentivise the production of drugs for small patient populations.

4 May 2016

BMJ experts reveal medical error as third main cause of death in the U.S

Medical error is the third leading cause of death in the US after heart disease and cancer, say experts in The BMJ today.

4 May 2016

Researchers find gene variants that predict adverse effects of hyperthyroidism drugs

Researchers and doctors at Uppsala University, along with Swedish and international collaboration partners, have found gene variants that predict the risk of a serious adverse reaction to drugs used for the treatment of hyperthyroidism. The results are published in The Lancet Diabetes & Endocrinology.

4 May 2016

Researchers investigate incidence of new position-related nerve deficit in spine surgery

Winner of the Sanford J. Larson, MD, PhD, Award, Gurpreet Surinder Gandhoke, MD, presented his research, Incidence of Position Related Neuropraxia in 4,489 Consecutive Patients Undergoing Spine Surgery. Role of SSEP Monitoring? during the 2016 American Association of Neurological Surgeons Annual Scientific Meeting.

4 May 2016

High prevalence of depression alongside COPD can impact overall health, treatment effectiveness

Although there have been discussions about chronic obstructive pulmonary disease (COPD), a condition impacting 24 million Americans, and depression, there has been little research showing the impact depression has on patients with COPD. Two studies published in the April issue of the journal CHEST found one in four patients with COPD suffer from depressive symptoms, and if not treated, those symptoms can have a negative effect on their overall health and treatment effectiveness.

4 May 2016

Study estimates 30% of outpatient oral antibiotic prescription in the U.S as inappropriate

An estimated 30 percent of outpatient oral antibiotic prescriptions in the U.S. in 2010-2011 may have been inappropriate, findings that support the need for establishing a goal for outpatient antibiotic stewardship, according to a study appearing in the May 3 issue of JAMA.

4 May 2016

Post-surgery death rates three times higher in low income countries, study shows

New research has shown that patients undergoing emergency surgery in lower income countries have a three times greater chance of dying than in higher income countries.

4 May 2016

Researchers discover critical new mechanism for genesis of heart failure

A weak heart is unable to pump an adequate amount of blood around the body. In Germany, this condition is now the commonest reason for patients to be admitted to hospital.

4 May 2016

Liposuction to manage lymphedema? An interview with Professor John Boyages

Lymphedema is persistent swelling of the arm and/or hand following biopsy or treatment of the axillary lymph nodes for patients with breast cancer. It is due to excess accumulation of protein‐rich fluid in body tissues.

4 May 2016

Stroke Awareness Month: Meridian Neuroscience provides latest information about stroke prevention, treatments

In observance of Stroke Awareness Month, Meridian Neuroscience is kicking off a series of informative community events, providing expert advice, tips, and the latest information about stroke prevention and treatments. The events will take place at Meridian Health locations throughout Monmouth and Ocean counties.

4 May 2016

Combination of two diagnostic tests can decrease chance of missing tumors by sevenfold

Cytopathology researchers at Houston Methodist Hospital recently found that combining two diagnostic tests, Pap and high-risk human papillomavirus (hrHPV), dramatically decreased the chance of missing tumors and high-grade lesions by sevenfold.

4 May 2016

Study assesses effect of chemoradiotherapy on survival of locally advanced pancreatic cancer patients

In a study appearing in the May 3 issue of JAMA, Pascal Hammel, M.D., of Beaujon Hospital, Clichy, France and colleagues assessed whether chemoradiotherapy improves overall survival of patients with locally advanced pancreatic cancer controlled after 4 months of gemcitabine-based induction chemotherapy, and assessed the effect of erlotinib on survival. Gemcitabine and erlotinib are drugs used to treat cancer.

4 May 2016

Riluzole drug can reverse key genetic changes linked to Alzheimer's disease

Aging takes its toll on the brain, and the cells of the hippocampus--a brain region with circuitry crucial to learning and memory--are particularly vulnerable to changes that can lead to Alzheimer's disease or cognitive decline. With the hope of counteracting the changes that can lead to these two conditions, researchers at Rockefeller University and their colleagues have begun examining the effects of a drug known to affect this circuitry.

4 May 2016

First-ever ACR-led imaging boot camp training for breast radiologists to be held in Jeddah

The American College of Radiology is partnering with GE Healthcare and King Faisal Specialist Hospital & Research Center to bring the first-ever ACR-led imaging boot camp training for breast radiologists to the Middle East. The three-day Breast Imaging Boot Camp to be held May 23-25 in Jeddah will provide up to 40 practicing radiologists in Saudi Arabia and the Middle East with intensive hands-on experience in mammography and breast ultrasonography.

4 May 2016

Ebola vaccine shows promise in clinical trials

"The results for tolerability, safety, and the immune response to the vaccine candidate are very promising," explains Prof Marylyn Addo. The antibodies which developed against the virus were still detectable after six months. Addo is convinced, "With this, a single vaccine could provide lasting protection against Ebola." The infectious disease specialist, who works for the German Center for Infection Research at the University Medical Center Hamburg Eppendorf in Hamburg, led the trial in Hamburg.

4 May 2016

NSCLC MAGE-A3 immunotherapy development halted

Disease-free survival is not prolonged with adjuvant MAGE-A3 immunotherapy in patients with surgically resected non-small-cell lung cancer, according to a placebo-controlled trial.

4 May 2016

Important changes in social lives of older adults indicate cognitive decline

Small changes in the social lives of older people are early red flags showing that their thought processes and brain functioning could be on the decline. This is according to Ashwin Kotwal of Brigham and Women's Hospital in the US, who led a study¹ in the Journal of General Internal Medicine, published by Springer.

3 May 2016

Influence of psychiatric comorbidities on all-cause readmissions following elective spine surgery

Winner of the Robert Florin Resident Award, Owoicho Adogwa, MD, presented his research, Association Between Baseline Affective Disorders and 30-day Readmission Rates in Patients Undergoing Elective Spine Surgery, during the 2016 American Association of Neurological Surgeons Annual Scientific Meeting.

3 May 2016

Xiao procedure lacks efficacy for bladder control in children

Researchers at Johns Hopkins All Children's Hospital report the results of a double-blinded randomized controlled trial of the "Xiao procedure" in children with spina bifida.

3 May 2016

Community-based social groups could support people with early-onset dementia

Community-based social groups could play a crucial role in empowering people with early-onset dementia, according to new UBC research.

3 May 2016

Hospital News and Research

Finding treatments for rare diseases: an interview with Dr Richard Thompson

BMJ experts reveal medical error as third main cause of death in the U.S

Researchers find gene variants that predict adverse effects of hyperthyroidism drugs

Researchers investigate incidence of new position-related nerve deficit in spine surgery

High prevalence of depression alongside COPD can impact overall health, treatment effectiveness

Study estimates 30% of outpatient oral antibiotic prescription in the U.S as inappropriate

Post-surgery death rates three times higher in low income countries, study shows

Researchers discover critical new mechanism for genesis of heart failure

Liposuction to manage lymphedema? An interview with Professor John Boyages

Stroke Awareness Month: Meridian Neuroscience provides latest information about stroke prevention, treatments

Combination of two diagnostic tests can decrease chance of missing tumors by sevenfold

Study assesses effect of chemoradiotherapy on survival of locally advanced pancreatic cancer patients

Riluzole drug can reverse key genetic changes linked to Alzheimer's disease

First-ever ACR-led imaging boot camp training for breast radiologists to be held in Jeddah

Ebola vaccine shows promise in clinical trials

NSCLC MAGE-A3 immunotherapy development halted

Important changes in social lives of older adults indicate cognitive decline

Influence of psychiatric comorbidities on all-cause readmissions following elective spine surgery

Xiao procedure lacks efficacy for bladder control in children

Community-based social groups could support people with early-onset dementia

Improving healthcare sustainability through carbon data

Managing vibration in IVF laboratories

A New Approach to Preventing Bladder Cancer Recurrence

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