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Researchers map the cellular diversity of entire salivary gland tumors

What goes on inside and between individual cells during the very earliest stages of tumor development? Single cell sequencing technologies and a mouse model have enabled researchers to comprehensively map the cellular diversity of whole salivary gland tumors and trace the path of cancer stem cells.

20 Feb 2020

Ancient primate microbiomes may yield more information about human development

Ancient human microbiomes are under the microscope for what they tell scientists about the people of long ago. A new study published in the journal Frontiers in Ecology and Evolution in February 2020 shows that the gut microbiome can adapt to new bacterial exposures, which allows humans to migrate to new locations successfully.

19 Feb 2020

UGA historian shines light on the evolutionary purpose of menopause

Menopause- that time in every woman's life when the ovaries no longer release an egg each month and menstruation ceases forever- is a rare thing among Earth's infinitely varied creatures.

18 Feb 2020

Researchers uncover genetic mechanisms that govern brain plasticity

Genetic mechanisms that govern brain plasticity - the brain's ability to change and adapt - have been uncovered by researchers at the University of Birmingham.

18 Feb 2020

Intratumoral heterogeneity linked to chemotherapy resistance in small-cell lung cancer

Small cell lung cancer accounts for 14% of all lung cancers and is often rapidly resistant to chemotherapy, resulting in poor clinical outcomes.

17 Feb 2020

Rutgers surgeon looks at link between WWI facial trauma and modern plastic surgery

Shahid Aziz has spent hours poring over the case histories of World War I soldiers who returned home with disfiguring facial injuries.

17 Feb 2020

Dormancy emerges as a natural evolutionary response to over-predation, study finds

Why do predators sometimes lay dormant eggs -- eggs which are hardy, but take a long time to hatch, and are expensive to produce?

16 Feb 2020

Research reveals new pathogenic mechanism for influenza NS1 protein

Influenza is a deadly virus, with about 290,000 to 650,000 deaths worldwide each year. When pandemics hit, the toll can soar: The Spanish flu of 1918 caused 40 million to 50 million deaths, the Asian flu of 1957 caused 2 million deaths, and the Hong Kong flu of 1968 caused 1 million deaths.

16 Feb 2020

Unique reproductive trait for seagrass revealed

Seagrasses have long been known as some of Earth's most remarkable organisms--descendants of flowering land plants that have re-colonized the ocean by developing traits that allow them to grow, pollinate, and release seeded fruits while fully immersed in salty seawater.

16 Feb 2020

Conspicuously large nerve cells have unique functions essential for survival

The brains of most fish and amphibian species contain a pair of conspicuously large nerve cells. These are the largest cells found in any animal brain.

14 Feb 2020

Adaptive gut microbiome of ancient humans could have been critical for evolution

The microbiome of our ancestors might have been more important for human evolution than previously thought, according to a new study published in Frontiers in Ecology and Evolution.

14 Feb 2020

Autophagy genes work against tumors in some ovarian cancers

Shedding light on a decades-old controversy, scientists at the Medical University of South Carolina and University of California at San Diego published findings in PLOS Genetics this month showing that autophagy or "self-eating" genes work against tumors in certain types of ovarian cancer.

13 Feb 2020

Moffitt research may provide a path toward improved multi-drug adaptive therapies

Personalized cancer treatments have greatly improved the lives of patients; however, many eventually develop resistance to these targeted drugs.

13 Feb 2020

Researchers identify control of a mitochondrial protective mechanism

Mitochondria are known as the "powerhouses" of cells. However, under critical pathophysiological conditions, they can use cellular energy for self-preservation.

12 Feb 2020

KAIST researchers identify mechanism that fuels a 'domino effect' in cancer drug resistance

KAIST researchers have identified mechanisms that relay prior acquired resistance to the first-line chemotherapy to the second-line targeted therapy, fueling a "domino effect" in cancer drug resistance.

11 Feb 2020

Fossilized dinosaur tail is home to a 60-million-year-old tumor

The fossilized tail of a young dinosaur that lived on a prairie in southern Alberta, Canada, is home to the remains of a 60-million-year-old tumor.

11 Feb 2020

Addressing the complexity of nasal tip contouring

The dramatic shift in how nasal tip surgery is being performed given changes in the intended goals and evolving techniques is highlighted in a Special Communication by and interview with Dean Toriumi, MD, published in the Official Journal of the American Academy of Facial Plastic and Reconstructive Surgery, Facial Plastic Surgery & Aesthetic Medicine, a peer-reviewed journal from Mary Ann Liebert, Inc., publishers.

11 Feb 2020

Finding a cure for canine gliomas may help find treatment for human brain cancer

Cancer research using experimental models--everything from cancer cells in a dish to patient tumors transplanted in mice--has been extremely useful for learning more about the disease and how we might treat it.

10 Feb 2020

Bats' fierce immune response to viruses could drive zoonotic emergence

It's no coincidence that some of the worst viral disease outbreaks in recent years -- SARS, MERS, Ebola, Marburg and likely the newly arrived 2019-nCoV virus -- originated in bats.

10 Feb 2020

First artificial enzyme with non-biological catalytic sites created

A new study published in the journal Nature Catalysis on February 10, 2020, reports the creation of a new artificial enzyme from two components, both non-biological in origin. This event marks the first such successful biological catalyst to contain a non-biological active site. The study shows that this type of synergistic combination of an amino acid not found in nature with a copper-based catalyst is capable of powerful catalytic action, unlike most other artificial enzymes.

10 Feb 2020