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Study shows more patients with advanced NSCLC may benefit from pembrolizumab

More patients with advanced non-small-cell lung cancer (NSCLC) could benefit from pembrolizumab, says Professor Roy Herbst, Chief of Medical Oncology, Yale Cancer Center and Smilow Cancer Hospital at Yale-New Haven, presenting promising results from the pivotal phase 2/3 KEYNOTE-010 trial at the first ESMO Asia Congress in Singapore), in conjunction with a publication in The Lancet.

22 Dec 2015

QMUL, Barts Health NHS Trust receive £10.2m to create new cardiovascular academic medical centre

Queen Mary University of London and Barts Health NHS Trust have received £10.2m from Barts Charity for the creation of a world-class cardiovascular academic medical centre at the Trust's Barts Heart Centre, St Bartholomew's Hospital.

22 Dec 2015

Bern study sheds light on the brain mechanism of arousal

Scientists from Bern have discovered a mechanism which is responsible for the rapid arousal from sleep and anesthesia in the brain. The results of their study suggest new strategies for the medical treatment of sleep disorders and recovery of consciousness in vegetative states.

22 Dec 2015

Commonly used diabetes drug may have potential to prevent, treat preeclampsia

An article published today in the American Journal of Obstetrics and Gynecology reports that a commonly-used drug for the treatment of diabetes, metformin, may have the potential to prevent and treat preeclampsia. Metformin has long been used to treat diabetes in both non-pregnant and pregnant patients, and is considered safe during pregnancy.

22 Dec 2015

Large doses of vitamin A reduce severity of gastrointestinal disease in mice

After observing that some gastrointestinal disease in premature human and mouse infants progresses only when certain immune system white blood cells go into inflammatory overdrive, Johns Hopkins researchers have found that giving large doses of vitamin A to mice converts those blood cells into inflammation suppressors and reduces the severity of the disease, compared to untreated mice.

22 Dec 2015

New study examines single 'transformer' proteins involved in cancer

A new study led by scientists at The Scripps Research Institute and St. Jude Children's Research Hospital shows how a protein involved in cancer twists and morphs into different structures.

22 Dec 2015

New MRI-based technology could help identify patients at risk of recurrent stroke

Patients who have had a stroke in the back of the brain are at greater risk of having another within two years if blood flow to the region is diminished, according to results of a multicenter study led by researchers at the University of Illinois at Chicago.

22 Dec 2015

Benjamin Wolozin receives $500,000 award in Alzheimer's Disease Drug Discovery Research

Research that leads to improved therapies for Alzheimer's disease (AD) patients is one goal of Boston University School of Medicine professor of pharmacology and neurology Benjamin Wolozin, MD, PhD. He was one of six researchers awarded a two-year, $500,000 award in Alzheimer's Disease Drug Discovery Research by the Edward N. & Della L. Thome Memorial Foundation.

22 Dec 2015

Email communications between patients, physicians improve overall health

A third of patients with chronic conditions who exchanged secure emails with their doctors said that these communications improved their overall health, according to a Kaiser Permanente study published today in the American Journal of Managed Care.

22 Dec 2015

Scientists uncover novel strategy to block cancer's spread, restore tumor vulnerability to chemotherapy

St. Jude Children's Research Hospital scientists have discovered how an aggressive tumor of the muscle and soft tissue hijacks an export pathway in cells to lay the groundwork for cancer progression and resistance to chemotherapy.

22 Dec 2015

Small airway-on-a-chip enables analysis of human COPD and asthma

A research team at the Wyss Institute for Biologically Inspired Engineering at Harvard University leveraged its organ-on-a-chip technology to develop a model of the human small airway in which lung inflammatory diseases, such as chronic obstructive pulmonary disease (COPD), the third leading cause of mortality worldwide, and asthma can be studied outside the human body.

22 Dec 2015

American College of Cardiology launches new STS/ACC TAVR In-Hospital Mortality Risk App

The American College of Cardiology has launched a new STS/ACC TAVR In-Hospital Mortality Risk App and an extensively overhauled the ACC AnticoagEvaluator App, bolstering its expansive Clinical App Collection. With these new and improved apps, the ACC continues to diversify the clinical content and decision support it offers clinicians in the mobile space.

22 Dec 2015

Premature babies at higher risk of developing autism in later childhood

Extremely premature babies run a much higher risk of developing autism in later childhood, and even during the neonate period differences are seen in the brains of those who do. This according to a new study by researchers from Karolinska Institutet and Karolinska University Hospital in Sweden.

22 Dec 2015

Patients with EGFR-mutated lung cancer benefit more from afatinib as first-line treatment

Patients with EGFR-activating mutations in advanced lung cancer seem to benefit more from afatinib than gefitinib as first-line treatment, researchers report at the first ESMO Asia 2015 Congress in Singapore.

21 Dec 2015

Alexza reports interim results from AZ-002 Phase 2a study in epilepsy patients

Alexza Pharmaceuticals, Inc. today announced interim results of its Phase 2a study of AZ-002 (Staccato alprazolam) in epilepsy patients. AZ-002 produced a dose-related decrease in mean Standardized Photosensivity Range (SPR), the primary endpoint in the study.

21 Dec 2015

New easy-to-use computer program can quickly identify drug-resistant infections

Scientists have developed an easy-to-use computer program that can quickly analyse bacterial DNA from a patient's infection and predict which antibiotics will work, and which will fail due to drug resistance. The software is currently being trialled in three UK hospitals to see whether it could help speed up diagnosis of drug-resistant infections and enable doctors to better target the prescription of antibiotics.

21 Dec 2015

New Griffith University study focuses on improving perinatal mental health in women

Addressing the barriers that can prevent midwives helping mothers overcome a fear of childbirth is the focus of a new study at Griffith University.

21 Dec 2015

Dietary cocoa flavanols may benefit cardiovascular health of patients with poor kidney function

Consuming a beverage containing cocoa flavanols improves blood vessel function in patients with kidney failure, according to a study appearing in an upcoming issue of the Clinical Journal of the American Society of Nephrology.

21 Dec 2015

CMFT adopts ZedScan system to improve cervical cancer care

DP Medical Systems Ltd has secured a deal with Central Manchester University Hospitals NHS Foundation Trust (CMFT) to adopt ZedScan™ as part of its cervical cancer care pathway.

From Zilico 21 Dec 2015

TUM scientists develop small molecule that may allow future patient-specific treatment of cancer tumours

Integrins help cells communicate with and adapt to their environment. Also cancer cells depend on their properties to survive and spread throughout the body. Now scientists at the Technical University of Munich have successfully developed a small, highly active molecule that binds to a specific integrin which operates in many types of cancer.

21 Dec 2015

Hospital News and Research

Study shows more patients with advanced NSCLC may benefit from pembrolizumab

QMUL, Barts Health NHS Trust receive £10.2m to create new cardiovascular academic medical centre

Bern study sheds light on the brain mechanism of arousal

Commonly used diabetes drug may have potential to prevent, treat preeclampsia

Large doses of vitamin A reduce severity of gastrointestinal disease in mice

New study examines single 'transformer' proteins involved in cancer

New MRI-based technology could help identify patients at risk of recurrent stroke

Benjamin Wolozin receives $500,000 award in Alzheimer's Disease Drug Discovery Research

Email communications between patients, physicians improve overall health

Scientists uncover novel strategy to block cancer's spread, restore tumor vulnerability to chemotherapy

Small airway-on-a-chip enables analysis of human COPD and asthma

American College of Cardiology launches new STS/ACC TAVR In-Hospital Mortality Risk App

Premature babies at higher risk of developing autism in later childhood

Patients with EGFR-mutated lung cancer benefit more from afatinib as first-line treatment

Alexza reports interim results from AZ-002 Phase 2a study in epilepsy patients

New easy-to-use computer program can quickly identify drug-resistant infections

New Griffith University study focuses on improving perinatal mental health in women

Dietary cocoa flavanols may benefit cardiovascular health of patients with poor kidney function

CMFT adopts ZedScan system to improve cervical cancer care

TUM scientists develop small molecule that may allow future patient-specific treatment of cancer tumours

Improving healthcare sustainability through carbon data

Managing vibration in IVF laboratories

A New Approach to Preventing Bladder Cancer Recurrence

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