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Scientists identify mechanisms underlying autoimmunity in Down syndrome

Scientists at the Icahn School of Medicine at Mount Sinai in New York have identified which parts of the immune system go awry and contribute to autoimmune diseases in individuals with Down syndrome.

22 Feb 2023

Study links obesity with 21 Alzheimer's disease-related genes

In a new study, researchers from The University of Texas Health Science Center at San Antonio (UT Health San Antonio) link obesity with 21 Alzheimer's disease-related genes, providing a potential mechanistic explanation for why Alzheimer's is sometimes more frequent among adults who experienced obesity in midlife.

22 Feb 2023

RBD-NTD-subunit protein vaccine provides a promising booster vaccination strategy capable of protecting against known SARS-CoV-2 variants

Researchers assessed the impact of SARS-CoV-2 spike NTD incorporation into the RBD protein vaccine.

22 Feb 2023

Researchers explore Mediterranean diet and its health benefits in managing obesity

A review article published in the journal Experimental Gerontology describes the utility of Mediterranean diet (MedDiet) in the prevention and management of obesity.

22 Feb 2023

A bitter battle over the ‘orphan drug’ program leaves patients’ pocketbooks at risk

A prescription drug that helps Lore Wilkinson walk and talk despite a rare muscle disease cost her so little for more than a decade that she didn't even use her insurance to pay for it.

22 Feb 2023

A growing burden of alcoholic hepatitis

A recent study published in the journal Medical Clinics of North America discussed the diagnosis, treatment, and pathophysiology of alcoholic hepatitis (AH).

21 Feb 2023

Research identifies potential treatment target for infantile spasms syndrome

New research from Tufts University School of Medicine and the Graduate School of Biomedical Sciences suggests that the timing of the death of certain inhibitory neurons in the brain shortly after birth may be at least partly to blame for infantile spasms syndrome (ISS), a rare but devastating form of epilepsy that develops most frequently between four and eight months of age but can emerge within weeks of birth until ages 4 or 5.

21 Feb 2023

University of Ottawa physician becomes first Canadian winner of the AFMC Wellness Award

The University of Ottawa's Dr. Mamta Gautam is the first awardee of the AFMC Wellness Award, a new national honor that recognizes an individual in Canada who has shown dedication to the promotion and advancement of the wellness of physicians, medical students, and others.

21 Feb 2023

A possible link between aggregation of SARS-CoV-2 proteins and protein misfolding diseases

A new study in the journal Nature Communications aimed to analyze the aggregation propensity in the proteins of both SARS-CoV-2 and SARS-CoV.

21 Feb 2023

Two new zebrafish models for studying the most common cause of Leigh syndrome developed

Researchers from Children's Hospital of Philadelphia (CHOP) developed two new zebrafish models for studying a specific genetic form of mitochondrial disease that represents the most common cause of Leigh syndrome.

21 Feb 2023

Researchers report the circulation of a novel MERS-like coronavirus in Malayan pangolins

Researchers reported the circulation of a novel MERS-like coronavirus among Malayan pangolins, Manis javanica HKU4-associated CoV (MjHKU4r-CoV).

21 Feb 2023

Family-centered care practices impacted for babies born to mothers with perinatal COVID-19

Most babies born to mothers with COVID-19 were separated after birth resulting in low breastfeeding and skin-to-skin contact rates during the height of the pandemic, according to a new global study.

21 Feb 2023

The impact of specific comorbidities and overall multimorbidity on the three mechanistically distinct phases of COVID-19

Researchers studied the impact of comorbidities in the three distinct phases of COVID-19.

21 Feb 2023

Research examines antibiotic use during COVID-19 by age

In a research letter published in JAMA Health Forum, researchers evaluated antibiotic prescriptions during severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection-associated health visits in outpatient settings by United States (US) residents aged ≤64 years who have commercial health insurance.

20 Feb 2023

How the human gut microbiota is shaped by diet

A new study in the journal Best Practice & Research Clinical Gastroenterology aimed to summarize the impact of specific nutrients as well as diets on the gut microbiota as well as the future perspectives of using diet as a therapeutic microbiome modulator.

20 Feb 2023

Propylene glycol prevents airborne transmission of respiratory viruses

Researchers assess the ability of propylene glycol to inactivate infection caused by respiratory viruses and prevent airborne transmission.

20 Feb 2023

Brexanolone inhibits key systemic inflammatory pathways associated with post-partum depression

Post-partum depression (PPD) develops after childbirth and affects both the mother's and the infant's health by preventing healthy bonding.

20 Feb 2023

In-depth assessment of muscle biopsies in patients with long COVID

Researchers analyzed skeletal muscle biopsies of patients with persistent fatigue and malaise post-exertion to determine the underlying mechanisms of long COVID.

20 Feb 2023

Is physical activity associated with the risks of hospitalization for common health conditions?

Researchers assessed the relationship between physical activity levels and hospitalization risk.

20 Feb 2023

Prior COVID highly protective against severe disease ten months post-infection

In a recent study published in the Lancet, researchers performed a systematic review of scientific literature published from inception up to September 31, 2022, that documented the reduction in risk of coronavirus disease 2019 (COVID-19) among individuals with a prior severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection vis-à-vis those with no COVID-19 history.

19 Feb 2023

Syndrome News and Research

Scientists identify mechanisms underlying autoimmunity in Down syndrome

Study links obesity with 21 Alzheimer's disease-related genes

RBD-NTD-subunit protein vaccine provides a promising booster vaccination strategy capable of protecting against known SARS-CoV-2 variants

Researchers explore Mediterranean diet and its health benefits in managing obesity

A bitter battle over the ‘orphan drug’ program leaves patients’ pocketbooks at risk

A growing burden of alcoholic hepatitis

Research identifies potential treatment target for infantile spasms syndrome

University of Ottawa physician becomes first Canadian winner of the AFMC Wellness Award

A possible link between aggregation of SARS-CoV-2 proteins and protein misfolding diseases

Two new zebrafish models for studying the most common cause of Leigh syndrome developed

Researchers report the circulation of a novel MERS-like coronavirus in Malayan pangolins

Family-centered care practices impacted for babies born to mothers with perinatal COVID-19

The impact of specific comorbidities and overall multimorbidity on the three mechanistically distinct phases of COVID-19

Research examines antibiotic use during COVID-19 by age

How the human gut microbiota is shaped by diet

Propylene glycol prevents airborne transmission of respiratory viruses

Brexanolone inhibits key systemic inflammatory pathways associated with post-partum depression

In-depth assessment of muscle biopsies in patients with long COVID

Is physical activity associated with the risks of hospitalization for common health conditions?

Prior COVID highly protective against severe disease ten months post-infection

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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