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RNF20 protein required for MLL-rearranged leukemia amplification

Acute myeloid leukemia (AML) is an aggressive blood cancer that is currently incurable in 70% of patients. In a bold effort, CSHL scientists are among those identifying and characterizing the molecular mechanisms responsible for this cancer in order to generate potential new therapeutics.

12 Feb 2013

Study shows effects of maternal obesity on fetuses

In a study to be presented on February 15 between 8 a.m. and 10 a.m. PST, at the Society for Maternal-Fetal Medicine's annual meeting, The Pregnancy Meeting -, in San Francisco, California, researchers from Tufts Medical Center will present findings showing the effects of maternal obesity on a fetus, specifically in the development of the brain.

11 Feb 2013

Maryland Higher Education Commission awards university status to Tai Sophia Institute

Maryland now has an accredited university dedicated to integrative health. Howard County–based Tai Sophia Institute announced today that it has been awarded university status by the Maryland Higher Education Commission and will change its name to Maryland University of Integrative Health (MUIH) effective March 1.

11 Feb 2013

Researchers identify miR-506 as potential therapeutic candidate for metastatic ovarian cancer

Researchers employed an extensive analysis of genomic information to identify a new, high-risk cohort of ovarian cancer patients, characterize their tumors, find a potential treatment and test it in mouse models of the disease.

11 Feb 2013

Valproate, pregnancy and IQ: an interview with Professor Kimford Meador

Valproate (sodium salt of valproic acid) is an anticonvulsant used in the treatment of epilepsy, migraine and bipolar disorder as well as some other off label psychiatric indications.

11 Feb 2013

Selumetinib shows high response rate for patients with low-grade serous ovarian cancer

Low-grade serous ovarian cancer is less common and aggressive than the high-grade variety, yet exceptionally difficult to treat when frontline therapy fails.

11 Feb 2013

Researchers discover miR-27b that regulates lipid levels in the blood

Researchers have identified a microRNA liver gene, miR-27b, which regulates lipid (cholesterol or fat) levels in the blood. This regulator gene controls multiple genes involved in dyslipidemia-abnormal blood cholesterol levels that can contribute to heart disease.

11 Feb 2013

Elsevier introduces Journal of Forensic Radiology and Imaging

Elsevier, a world-leading provider of scientific, technical and medical information products and services, announces the launch of Journal of Forensic Radiology and Imaging (JOFRI), the official new journal of the International Society of Forensic Radiology and Imaging (ISFRI).

11 Feb 2013

Obesity research expert receives Queen Elizabeth II Diamond Jubilee Medal

ParticipACTION, the national voice of physical activity and sport participation in Canada, and the Children's Hospital of Eastern Ontario (CHEO) Research Institute are pleased to announce that Dr. Mark Tremblay has been awarded a Queen Elizabeth II Diamond Jubilee Medal from the Governor General of Canada. Medals are awarded to individuals who have distinguished themselves from others through their achievements and sustained contribution to their field.

11 Feb 2013

Case Western Reserve receives $220,000 grant to study gastric cancers

The Case Western Reserve University School of Medicine has received a $220,000 grant from the DeGregorio Family Foundation to study gastric cancers, which remain among the most deadly forms of disease.

11 Feb 2013

Parenteral nutrition safety: an interview with Dr. Phil Ayers, A.S.P.E.N PN Safety Task Force Chair and Dr. Peggi Guenter, Director of the American Society for Parenteral and Enteral Nutrition (A.S.P.E.N.)

Parenteral nutrition is intravenous nutrition for patients who are unable to eat or be tube fed. It is used with more than 300,000 patients per year - a quarter of whom are children and newborns.

11 Feb 2013

Pelosi again rejects proposal to change Medicare

House Democratic leader, in television interview discussing scheduled budget cuts and the national economy, says she hasn't seen evidence that raising the Medicare eligibility age will save money. Republican Rep. Cantor, on a different Sunday morning program, says the government has to find a way to cut spending.

11 Feb 2013

Nine suggestions to prevent sexual abuse among children

Pediatricians know that when they discuss seat belt, bicycle and water safety during annual wellness visits they are helping to reduce a child's risk of harm. Those same visits should include messages about personal space and privacy, says Dr. Martin A. Finkel, an internationally known expert in the prevention and treatment of child sexual abuse, and he is urging pediatricians to begin a dialogue that will help children avoid the physical and mental health consequences of sexual abuse.

11 Feb 2013

Epithelium able to sense bladder fullness through activity of integrins

If you have an overactive bladder or incontinence, help could be on the way. A new research report published online in the FASEB Journal, shows that the epithelium, a thin layer of cells which line the surface of the bladder, is able to sense how full the bladder is through the action of a family of proteins called integrins.

11 Feb 2013

Study identifies 12 important postoperative complication signs in colorectal surgical patients

Colorectal surgical patients are often discharged from the hospital with vague guidance on how to recognize complications, but researchers at the Michael DeBakey Veterans Administration (VA) Medical Center and Baylor College of Medicine, Houston, aim to change that scenario.

11 Feb 2013

FDA issues draft guidance on developing new treatments for Alzheimer's

Today, the U.S. Food and Drug Administration issued a proposal designed to assist companies developing new treatments for patients in the early stages of Alzheimer's disease, before the onset of noticeable (overt) dementia.

11 Feb 2013

Bishops reject HHS plan for contraception coverage

The Catholic leaders say the compromise doesn't offer enough safeguards for religious institutions, and that they will continue to fight the administration on the mandate.

11 Feb 2013

APOBEC3B enzyme plays a key role in breast cancer

Researchers at the University of Minnesota have uncovered a human enzyme responsible for causing DNA mutations found in the majority of breast cancers. The discovery of this enzyme - called APOBEC3B - may change the way breast cancer is diagnosed and treated.

10 Feb 2013

$Scientists discover 24 new genes that cause refractive errors and myopia$

Scientists discover 24 new genes that cause refractive errors and myopia

An international team of scientists led by King's College London has discovered 24 new genes that cause refractive errors and myopia (short-sightedness).

10 Feb 2013

Fighting NTDs has greater effect of empowering women

"As Melinda Gates captured through her blog piece by envisioning the conversation of women's role in the year 2030, I would also like to offer my voice in the spirit of conversation," Mawish Raza, a communications intern with the Global Network for Neglected Tropical Diseases (NTDs), writes in the network's "End the Neglect" blog, adding, "My hope is that by 2030, women are not only given the advantage to circumvent neglected and un-neglected diseases, but that they are able to make better use of their restored health to drive their communities out of poverty and forward into progress."

10 Feb 2013