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New study calls for new treatments for carbapenem-resistant Enterobacteriaceae infection

Researchers at The Medicines Company presented data from a multi-national cohort that demonstrates the mortality and morbidity, and poor outcomes, associated with current therapies in patients with infections due to carbapenem-resistant Enterobacteriaceae (CRE). The data from this analysis has guided the design of the company’s on-going clinical studies of its Phase 3 compound, CARBAVANCE® (meropenem/RPX7009) and was presented at the Interscience Conference of Antimicrobial Agents and Chemotherapy (ICAAC) and the International Congress of Chemotherapy and Infection (ICC) joint meeting in San Diego, CA.

22 Sep 2015

Pneumococcal and rotavirus vaccines lead to rapid reduction in pediatric hospital burden

Researchers show that the introduction of both pneumococcal conjugate vaccines (PCVs) and rotavirus vaccines (RVs) led to the rapid and dramatic reduction in hospital burden of both winter diarrhea and respiratory infections within <5 years post introduction of the vaccines.

22 Sep 2015

BWH, DFCI researchers receive $10 million to test effectiveness of aspirin in women with breast cancer

Researchers from Brigham and Women's Hospital and Dana-Farber Cancer Institute have received a $10 million Breakthrough Award from the Department of Defense's Office of the Congressionally Directed Medical Research Program to test whether aspirin helps women with breast cancer avoid recurrence and live longer.

22 Sep 2015

Study compares effectiveness of nafcillin and cefazolin in patients with MSSA blood stream infections

Research comparing clinical outcomes between patients receiving nafcillin and cefazolin for treatment of methicillin-susceptible Staphylococcus aureus (MSSA) bacteremia shows that overall treatment failure rate among patients receiving cefazolin was no worse than nafcillin, and significantly fewer adverse effects were documented for those receiving cefazolin.

22 Sep 2015

Arsenic trioxide feasible in low-, high-risk acute promyelocytic leukaemia

The use of arsenic trioxide instead of idarubicin in combination with all-trans retinoic acid is a feasible option in patients with acute promyelocytic leukaemia, regardless of risk level, suggests a phase III trial.

21 Sep 2015

Study identifies link between kidney stones in children and atherosclerosis

A recent study published in The Journal of Pediatrics is the first to examine and identify a link between kidney stones in children and thickened or hardened arteries — precursors to a wide variety of cardiovascular diseases. Understanding the connection between kidney stones and cardiovascular risk factors in children may help physicians and parents implement prevention measures to reduce future risk of stroke, heart attack or other forms of vascular disease for affected children.

21 Sep 2015

New initiative aims to improve early detection, treatment of mitochondrial disease in Canada

The MitoCanada Foundation has announced a national research venture focused on improving the early detection and treatment of mitochondrial disease in Canada.

21 Sep 2015

Prime Healthcare Services agrees to acquire Lehigh Regional Medical Center

Prime Healthcare Services has signed a definitive agreement to acquire the 88-bed Lehigh Regional Medical Center located in Lehigh Acres, Florida and related businesses, including physician clinic operations and ancillary services from subsidiaries of Community Health Systems.

21 Sep 2015

PDL BioPharma purchases portion of royalties on expected sales of AcelRx's Zalviso

PDL BioPharma, Inc. announced today that it has acquired a portion of the royalties on expected sales of AcelRx Pharmaceuticals Inc.'s Zalviso (sufentanil sublingual tablet system) in the European Union, Switzerland and Australia by its commercial partner, Grunenthal.

21 Sep 2015

Consumer's financial resources influence quality of nutrition, diet

Quality of nutrition and diet is influenced by the consumer's financial resources, reveals a study funded by the Swiss National Science Foundation. Some immigrants have a healthier diet than people born in Switzerland.

21 Sep 2015

Higher doses of hydrocortisone not linked to neurodevelopmental impairments in low birth weight infants

Hydrocortisone is one of the 15 most frequently prescribed medications in extremely low birth weight (?1000 g) infants in the newborn intensive care unit (NICU).

21 Sep 2015

Researchers develop new method to capture how brain cells interact

Interactions between brain cells hold the key to healthy brain function and cognition, but many of those interactions are notoriously difficult to study.

21 Sep 2015

Promising new innovations in drug development, health monitoring may improve drug safety in the future

Adverse drug reactions are harmful to patients and a major burden for healthcare providers, governments and the pharmaceutical industry. But promising new breakthroughs in drug development and health monitoring may enhance drug safety in the future, according to an editorial to be published in the next edition of the British Journal of Clinical Pharmacology.

21 Sep 2015

BMC significantly reduces emergency wait time, improves SCD care for pediatric patients

Boston Medical Center has significantly reduced the amount of time that pediatric patients experiencing pain from sickle cell disease (SCD) wait before receiving pain medication when they come to the emergency department. The hospital's quality improvement initiative cut the wait time by more than 50 percent, from an average of 56 minutes to 23 minutes, from triage to administration of the first dose of pain medication.

21 Sep 2015

Study: Neighborhood factors do not influence EMS use for acute stroke as strongly as individual factors do

Neighborhood factors do not influence the use of emergency medical services (EMS) for stroke as strongly as individual factors do, despite earlier indications that socio-demographic characteristics of the neighborhood explain low rates of EMS activation for this life-threatening emergency.

21 Sep 2015

Researchers develop 3D-printed guide that helps regrow nerves after injury

A national team of researchers has developed a first-of-its-kind, 3D-printed guide that helps regrow both the sensory and motor functions of complex nerves after injury. The groundbreaking research has the potential to help more than 200,000 people annually who experience nerve injuries or disease.

21 Sep 2015

Adolescents with bulimia nervosa recover faster when parents involved in treatment

Involving parents in the treatment of adolescents with bulimia nervosa is more effective than treating the patient individually, according to a study led by Daniel Le Grange, PhD, Benioff UCSF Professor in children's health in the departments of psychiatry and pediatrics at UCSF Benioff Children's Hospital San Francisco, and James Lock, MD, PhD, professor of psychiatry at Stanford University School of Medicine.

21 Sep 2015

Genetically engineered vaccine eradicates precancerous cervical lesions

Scientists have used a genetically engineered vaccine to successfully eradicate high-grade precancerous cervical lesions in nearly one-half of women who received the vaccine in a clinical trial. The goal, say the scientists, was to find nonsurgical ways to treat precancerous lesions caused by HPV.

18 Sep 2015

Thomas Jefferson University provides routine genomic fingerprinting to cancer patients

Cancer medicine is moving towards understanding what drives each particular patient's cancer. But not every patient has had access to this level of individualized care.

18 Sep 2015

Obese patients with type 2 diabetes should be prioritised for obesity surgery over those without diabetes

New research published in The Lancet Diabetes & Endocrinology suggests that, when considering overall costs of healthcare, obese patients with type 2 diabetes, especially those with recent disease onset, should be prioritised for obesity surgery over those without type 2 diabetes, since many patients see a reversal of diabetes after surgery and thus need fewer expensive diabetes medications or treatment for complications in future.

18 Sep 2015

Hospital News and Research

New study calls for new treatments for carbapenem-resistant Enterobacteriaceae infection

Pneumococcal and rotavirus vaccines lead to rapid reduction in pediatric hospital burden

BWH, DFCI researchers receive $10 million to test effectiveness of aspirin in women with breast cancer

Study compares effectiveness of nafcillin and cefazolin in patients with MSSA blood stream infections

Arsenic trioxide feasible in low-, high-risk acute promyelocytic leukaemia

Study identifies link between kidney stones in children and atherosclerosis

New initiative aims to improve early detection, treatment of mitochondrial disease in Canada

Prime Healthcare Services agrees to acquire Lehigh Regional Medical Center

PDL BioPharma purchases portion of royalties on expected sales of AcelRx's Zalviso

Consumer's financial resources influence quality of nutrition, diet

Higher doses of hydrocortisone not linked to neurodevelopmental impairments in low birth weight infants

Researchers develop new method to capture how brain cells interact

Promising new innovations in drug development, health monitoring may improve drug safety in the future

BMC significantly reduces emergency wait time, improves SCD care for pediatric patients

Study: Neighborhood factors do not influence EMS use for acute stroke as strongly as individual factors do

Researchers develop 3D-printed guide that helps regrow nerves after injury

Adolescents with bulimia nervosa recover faster when parents involved in treatment

Genetically engineered vaccine eradicates precancerous cervical lesions

Thomas Jefferson University provides routine genomic fingerprinting to cancer patients

Obese patients with type 2 diabetes should be prioritised for obesity surgery over those without diabetes

Improving healthcare sustainability through carbon data

Managing vibration in IVF laboratories

A New Approach to Preventing Bladder Cancer Recurrence

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