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Researchers present new program to evaluate clinical relevance of genetic variants

Millions of genetic variants have been discovered over the last 25 years, but interpreting the clinical impact of the differences in a person's genome remains a major bottleneck in genomic medicine. In a paper published in The New England Journal of Medicine on May 27, a consortium including investigators from Brigham and Women's Hospital and Partners HealthCare present ClinGen, a program to evaluate the clinical relevance of genetic variants for use in precision medicine and research.

27 May 2015

Carbon monoxide may actually protect the brain from damage after subarachnoid hemorrhage

Carbon monoxide is known by many as a poisonous gas that causes brain injury and other neurological symptoms, including memory loss and confusion. But a new study led by investigators at Beth Israel Deaconess Medical Center suggests the opposite may be true: When administered in small, carefully controlled amounts, carbon monoxide may actually protect the brain from damage following subarachnoid hemorrhage, a devastating stroke that results from bleeding in the brain.

27 May 2015

$Subclinical hyperthyroidism linked to increased fracture risk$

Subclinical hyperthyroidism linked to increased fracture risk

In an analysis that included more than 70,000 participants from 13 studies, subclinical hyperthyroidism was associated with an increased risk for hip and other fractures including spine, according to a study in the May 26 issue of JAMA. Subclinical hyperthyroidism is a low serum thyroid-stimulating hormone concentration in a person without clinical symptoms and normal thyroid hormone concentrations on blood tests.

27 May 2015

Scientists identify molecular 'lock' that enables Ebola virus to gain entry to cells

An international team including scientists from Albert Einstein College of Medicine of Yeshiva University and the U.S. Army Medical Research Institute of Infectious Diseases has identified the molecular "lock" that the deadly Ebola virus must pick to gain entry to cells.

27 May 2015

ProMedica, UT partner to build one of nation’s top academic medical centers in northwest Ohio

In just 10 years, this nation could have a shortage of between 46,000 and 90,000 physicians. This is according to a recent report released by the Association of American Medical Colleges. Major contributing factors include a growing and aging population, plus one-third of practicing physicians with plans to retire in the next decade. These shortages are expected to be particularly challenging for communities the size of Toledo competing with larger metropolitan areas to attract future doctors and caregivers.

27 May 2015

Medic Vision announces introduction of SafeCT Dose Reporting for healthcare providers

Medic Vision Imaging Solutions, Ltd., the leading innovator of vendor-independent image enhancement solutions for low-dose CT exams, announced today the introduction and availability of SafeCT Dose Reporting. Healthcare facilities can now, for the first time, use a single software platform to meet their low dose CT imaging needs while also conforming to CT dose monitoring and reporting standards.

27 May 2015

AbbVie announces new results from Phase 3 GIFT-I study in GT1b HCV infected Japanese patients

AbbVie presented new results from the Phase 3 GIFT-I study of its investigational, all-oral, interferon (IFN)- and ribavirin (RBV)-free, two direct-acting antiviral treatment with ombitasvir/paritaprevir/ritonavir at the Annual Meeting of the Japan Society of Hepatology in Kumamoto, Japan.

27 May 2015

Emergency medicine faces special challenges with changeover in medical diagnosis codes

Emergency medicine faces special challenges during this fall's changeover in how medical diagnoses are coded. Nearly a quarter of all ER clinical encounters could pose difficulties.

27 May 2015

People who have higher HDL function experience fewer heart attacks later in life

HDL is the 'good cholesterol' that helps remove fat from artery walls, reversing the process that leads to heart disease. Yet recent drug trials and genetic studies suggest that simply pushing HDL levels higher doesn't necessarily reduce the risk of heart disease.

27 May 2015

Toronto researchers design simple chip for faster, easier detection of antibiotic-resistant bacteria

We live in fear of 'superbugs': infectious bacteria that don't respond to treatment by antibiotics, and can turn a routine hospital stay into a nightmare. A 2015 Health Canada report estimates that superbugs have already cost Canadians $1 billion, and are a "serious and growing issue." Each year two million people in the U.S. contract antibiotic-resistant infections, and at least 23,000 people die as a direct result.

27 May 2015

Canadian researchers shed light on molecular dynamics of chronic pain

Chronic pain affects hundreds of millions of people worldwide and is a major cause of disability, causing more disability than cancer and heart disease. Canadian researchers, including Michael Salter at SickKids are shedding light on the molecular dynamics of chronic pain. They have uncovered a critical role for a class of cells present in the brain and spinal cord, called microglia, in pain.

27 May 2015

New stem-cell based therapy provides pain relief, reduces severity of RDEB in children

Promising results from a trial of a new stem-cell based therapy for a rare and debilitating skin condition have been published in the Journal of Investigative Dermatology. The therapy, involving infusions of stem cells, was found to provide pain relief and to reduce the severity of this skin condition for which no cure currently exists.

27 May 2015

Spouses of patients receiving hospice care report reduced depression symptoms

Spouses of patients receiving hospice for three or more days more frequently reported reduced depression symptoms, compared to surviving spouses of patients who did not receive hospice, according to a study led by researchers at the Icahn School of Medicine at Mount Sinai published online today in JAMA Internal Medicine.

27 May 2015

Risk for obesity-associated diseases significantly higher for males than females

Obesity may be tougher on male immune systems than females, a new study in mice at the University of Michigan Medical School suggests.

27 May 2015

Verax Biomedical obtains FDA clearance to expand use of Verax Platelet PGD test

Verax Biomedical today announced that the company has gained FDA clearance to expand the use of its Verax Platelet PGD test—a rapid test for the detection of bacterial contamination in platelets intended for transfusion. The new FDA clearance makes the Verax Platelet PGD test the only rapid test on the market cleared by the FDA to check every commonly distributed platelet type in the United States.

27 May 2015

Alternative generic strategy for breast cancer treatment

Maxing out the inherently stressed nature of treatment-resistant breast cancer cells thwarts their adaptive ability to evolve genetic workarounds to treatment, a new study suggests.

27 May 2015

West Tennessee Healthcare, HealthSouth partner to jointly operate inpatient rehabilitation hospital in Jackson

West Tennessee Healthcare and HealthSouth Corporation have signed an agreement to form a joint venture to own and operate a 48-bed inpatient rehabilitation hospital in Jackson, Tennessee.

27 May 2015

GSC introduces Change4Life health portal for Canadians

Canadians will now be rewarded for good health behaviour through Green Shield Canada's Change4Life health portal, a first in the country. The online health management site not only supports and encourages healthy behaviours, it will reward them. This marks the first time a Canadian health benefits provider will attempt to positively influence Canadian employees' health behaviour through incentives and rewards.

26 May 2015

CORD calls upon governments, others to join forces to make Canada's Rare Disease Strategy a reality

Today, on Parliament Hill, the Canadian Organization for Rare Disorders released Canada's Rare Disease Strategy and called upon the federal, provincial and territorial governments along researchers, healthcare providers, educators, employers, and the patient community to join forces to make the Strategy a reality.

26 May 2015

Researchers find way to prevent, reduce or delay cannabis use amongst at-risk youth

Responding to rapidly shifting legal and cultural environments, researchers at the University of Montreal and CHU Sainte-Justine Children's Hospital have found a way to prevent, reduce or delay cannabis use amongst some at-risk youth. Cannabis users are at risk of neurocognitive deficits, reduced educational and occupational attainment, motor vehicle accidents, exacerbation of psychiatric symptoms, and precipitation of psychosis.

26 May 2015

Hospital News and Research

Researchers present new program to evaluate clinical relevance of genetic variants

Carbon monoxide may actually protect the brain from damage after subarachnoid hemorrhage

Subclinical hyperthyroidism linked to increased fracture risk

Scientists identify molecular 'lock' that enables Ebola virus to gain entry to cells

ProMedica, UT partner to build one of nation’s top academic medical centers in northwest Ohio

Medic Vision announces introduction of SafeCT Dose Reporting for healthcare providers

AbbVie announces new results from Phase 3 GIFT-I study in GT1b HCV infected Japanese patients

Emergency medicine faces special challenges with changeover in medical diagnosis codes

People who have higher HDL function experience fewer heart attacks later in life

Toronto researchers design simple chip for faster, easier detection of antibiotic-resistant bacteria

Canadian researchers shed light on molecular dynamics of chronic pain

New stem-cell based therapy provides pain relief, reduces severity of RDEB in children

Spouses of patients receiving hospice care report reduced depression symptoms

Risk for obesity-associated diseases significantly higher for males than females

Verax Biomedical obtains FDA clearance to expand use of Verax Platelet PGD test

Alternative generic strategy for breast cancer treatment

West Tennessee Healthcare, HealthSouth partner to jointly operate inpatient rehabilitation hospital in Jackson

GSC introduces Change4Life health portal for Canadians

CORD calls upon governments, others to join forces to make Canada's Rare Disease Strategy a reality

Researchers find way to prevent, reduce or delay cannabis use amongst at-risk youth

Single-cell proteomics: Revealing proteome diversity from cellular heterogeneity to non-canonical biology

Improving healthcare sustainability through carbon data

Managing vibration in IVF laboratories

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