Immune Response News and Research

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New vaccine platform can better induce anti-malaria immunity in the liver

Malaria remains a deadly disease that affects people worldwide, particularly in Africa. Caused by a parasite that can enter the human bloodstream via mosquito bite, the parasites can then infect and reproduce within the person's liver.

16 Sep 2021

Fatal COVID-19 infections linked to poor immune responses and elevated MAIT cell activation

The mortality rate of COVID-19 patients requiring mechanical ventilation is 30-40%, however, the immunological factors associated with death in critically ill COVID-19 patients are poorly understood.

16 Sep 2021

Study highlights the importance of deeply exploring the immune responses against cancer

Over the past decade, scientists have been exploring vaccination as a way to help fight cancer. These experimental cancer vaccines are designed to stimulate the body's own immune system to destroy a tumor, by injecting fragments of cancer proteins found on the tumor.

16 Sep 2021

Unique imaging technique sheds light on how cells related to IBD affect intestinal tissues

New "maps" of hundreds of thousands of cells related to inflammatory bowel disease shed greater light on their effects on intestinal tissues through a newly utilized imaging technique called "imaging mass cytometry."

16 Sep 2021

Pfizer vaccine induces strong immunity in elderly with prior COVID-19

A new study discusses the vaccination response in elderly who were vaccinated with one dose of the Pfizer vaccine 15 months after contracting COVID-19.

16 Sep 2021

UTSW researchers discover how vitamin A enters immune cells in the intestines

Immunologists and geneticists at UT Southwestern Medical Center have discovered how vitamin A enters immune cells in the intestines – findings that could offer insight to treat digestive diseases and perhaps help improve the efficacy of some vaccines.

16 Sep 2021

Reproductive specialist highlights the need to investigate menstrual changes after covid-19 vaccination

Some women say their periods change after getting a covid-19 vaccination. In The BMJ today, Dr Victoria Male, a reproductive specialist at Imperial College London, says a link between menstrual changes after covid-19 vaccination is plausible and should be investigated.

16 Sep 2021

Live oral SARS-CoV-2 vaccine provides partial protection in Rhesus Macaques

A new study describes the partial protection against respiratory infection with SARS-CoV-2 following gut inoculation with a live attenuated virus.

16 Sep 2021

New modeling on efficacy of BioNTech-Pfizer's SARS-CoV-2 vaccine against variants

In order to address these issues, scientists from Xitific LTD and IDEAPharma in the UK proposed a novel approach to the framework of immune correlates, built upon the previous research. The framework formulated by the authors was developed for the mRNA-based vaccinations but could be applied to the other variations.

16 Sep 2021

Research reveals vital role of protein-coding gene in tumor development and immune therapy response

Researchers from the Case Comprehensive Cancer Center uncovered the potentially important role of the protein-coding gene, MYO10, in tumor development and immune therapy response. Their findings were published today in Science Advances.

16 Sep 2021

Analysis of the immune landscape in mild-to-moderate COVID-19

A new study includes an analysis of plasma cytokine levels, peripheral blood immune cell composition, and SARS-CoV-2 specific Igs in COVID-19.

15 Sep 2021

Study looks at exposure to different SARS-CoV-2 variants and immune response

Researchers compared the responses against several SARS-CoV-2 VoCs in sera from individuals exposed to variant infection, vaccination, or both.

15 Sep 2021

COVID mRNA vaccines display weakened immune response with age and diminish over time, according to new study

Researchers from Simon Fraser University in Canada decided to investigate the magnitude of immunity in mRNA vaccines for COVID-19.

15 Sep 2021

Study on B lymphocytes may contribute to the optimization of vaccines

Our bodies can fine-tune the immune response to an infection and make it proportional to the threat at hand.

15 Sep 2021

Natural SARS-CoV-2 infection induces more durable immunity than vaccination study suggests

Scientists from the USA have demonstrated that immunity induced by mRNA-based COVID-19 vaccines in previously SARS-CoV-2-infected people has the highest robustness and durability with cross-reactivity against different viral variants.

15 Sep 2021

Deep profiling of SARS-CoV-2 immune response amongst the mildly symptomatic

In a research paper recently uploaded to the medRxiv* preprint server by Capelle et al. (September 2nd, 2021), the immune response of mild and hospitalized COVID-19 patients is compared, finding that early T-cell response is a vital indicator of SARS-CoV-2 disease severity.

15 Sep 2021

Quantification of salivary IgG and IgA against SARS-CoV-2

Salivary antibody levels are many fold lower than found in blood serum, Immunoglobulin G (IgG) in the saliva is mainly sourced from leakage from the gingival surface and Immunoglobulin A (IgA) from mucosal membranes.

15 Sep 2021

Flu shots and COVID-19 immunity

A new paper finds that the influenza vaccine may influence both the response to and incidence of infection by the SARS-CoV-2.

14 Sep 2021

MS patients receiving aCD20 treatment mount robust T-cell responses to COVID-19 vaccines

New research shows that Multiple Sclerosis (MS) patients undergoing anti-CD20 (aCD20) treatment – which depletes the B cells that contribute to the MS attacks – are able to mount robust T-cell responses to the mRNA COVID-19 vaccines, despite having a muted antibody response to the vaccines.

14 Sep 2021

Low dose of Moderna COVID-19 vaccine generates durable immune response

A new study from La Jolla Institute for Immunology (LJI) scientists helps answer the question: how long does immunity against COVID-19 last in vaccinated people?

14 Sep 2021

Immune Response News and Research

New vaccine platform can better induce anti-malaria immunity in the liver

Fatal COVID-19 infections linked to poor immune responses and elevated MAIT cell activation

Study highlights the importance of deeply exploring the immune responses against cancer

Unique imaging technique sheds light on how cells related to IBD affect intestinal tissues

Pfizer vaccine induces strong immunity in elderly with prior COVID-19

UTSW researchers discover how vitamin A enters immune cells in the intestines

Reproductive specialist highlights the need to investigate menstrual changes after covid-19 vaccination

Live oral SARS-CoV-2 vaccine provides partial protection in Rhesus Macaques

New modeling on efficacy of BioNTech-Pfizer's SARS-CoV-2 vaccine against variants

Research reveals vital role of protein-coding gene in tumor development and immune therapy response

Analysis of the immune landscape in mild-to-moderate COVID-19

Study looks at exposure to different SARS-CoV-2 variants and immune response

COVID mRNA vaccines display weakened immune response with age and diminish over time, according to new study

Study on B lymphocytes may contribute to the optimization of vaccines

Natural SARS-CoV-2 infection induces more durable immunity than vaccination study suggests

Deep profiling of SARS-CoV-2 immune response amongst the mildly symptomatic

Quantification of salivary IgG and IgA against SARS-CoV-2

Flu shots and COVID-19 immunity

MS patients receiving aCD20 treatment mount robust T-cell responses to COVID-19 vaccines

Low dose of Moderna COVID-19 vaccine generates durable immune response

Understanding the DNA Damage Response in Innate Immunity eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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