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New NIAID grant to support development of topical microbicide gel for HIV and HSV-2 infections

A new grant from the National Institute of Allergy and Infectious Diseases (NIAID) will support the development of a topical microbicide gel for drug delivery. The innovative gel formulation will be a combination therapy against human immunodeficiency virus (HIV) and herpes simplex virus type 2 (HSV-2) infections in women.

25 Jul 2012

Bill Gates stresses importance of investment in both HIV treatment and research for vaccines, microbicides

In a symposium session on Monday at the XIX International AIDS Conference in Washington, D.C., politicians and public health experts joined Bill & Melinda Gates Foundation Co-Chair Bill Gates for a discussion about improving effectiveness and efficiency in the HIV/AIDS response, the Washington Post reports.

25 Jul 2012

Moderate-to-severe TBI can disrupt proteins that regulate enzyme associated with Alzheimer's

A study, performed in mice and utilizing post-mortem samples of brains from patients with Alzheimer's disease, found that a single event of a moderate-to-severe traumatic brain injury (TBI) can disrupt proteins that regulate an enzyme associated with Alzheimer's.

25 Jul 2012

Vanderbilt researchers receives new $2.1M grant to develop microbrain bioreactor

Take a millionth of a human brain and squeeze it into a special chamber the size of a mustard seed. Link it to a second chamber filled with cerebral spinal fluid and thread both of them with artificial blood vessels in order to create a microenvironment that makes the neurons and other brain cells behave as if they were in a living brain. Then surround the chambers with a battery of sensors that monitor how the cells respond when exposed to minute quantities of dietary toxins, disease organisms or new drugs under development.

25 Jul 2012

Deep look into how brain mechanisms for memory retrieval differ between adults and children

Neuroscientists from Wayne State University and the Massachusetts Institute of Technology (MIT) are taking a deeper look into how the brain mechanisms for memory retrieval differ between adults and children.

25 Jul 2012

New algorithm can help scientists predict gene and drug interactions

Researchers from Mount Sinai School of Medicine have developed a new computational method that will make it easier for scientists to identify and prioritize genes, drug targets, and strategies for repositioning drugs that are already on the market. By mining large datasets more simply and efficiently, researchers will be able to better understand gene-gene, protein-protein, and drug/side-effect interactions. The new algorithm will also help scientists identify fellow researchers with whom they can collaborate.

25 Jul 2012

Insight into possible new approaches in vaccine development for blood-borne infections and HIV

White blood cells called neutrophils, which are the first line of defense against infection, play an unexpected role by boosting antibody production, according to research led by Mount Sinai School of Medicine. The findings suggest neutrophils have multiple roles within the immune system and function at levels previously unknown to the scientific community. The research, published in Nature Immunology, provides groundbreaking insight into possible new approaches in vaccine development for blood-borne infections and HIV.

25 Jul 2012

Researchers plan to develop new rehabilitation tool for stroke victims

Researchers at the University of Luxembourg, along with their international partners, want to develop an easy-to-use, self-motivating tool that stroke patients can use in their rehabilitation process. The 4.4 million euro project is funded by the European Commission Seventh Framework Programme.

25 Jul 2012

New classification scheme for psychiatric symptoms

The traditional approach to psychiatric diagnosis is based on grouping patients on the basis of symptom clusters. This approach to diagnosis has a number of problems, as symptoms are not necessarily specific to a single diagnosis.

25 Jul 2012

Colonoscopy with polypectomy decreases colorectal cancer incidence and mortality

A study from researchers in Switzerland found that colonoscopy with polypectomy significantly reduces colorectal cancer incidence and colorectal cancer-related death in the general population.

25 Jul 2012

N.J. Dental School receives HSS grant to address nationwide shortage of faculty

The University of Medicine and Dentistry of New Jersey-New Jersey Dental School (NJDS) is helping to address what is perhaps dental education's greatest challenge yet: a critical nationwide shortage of faculty.

24 Jul 2012

Blood flow in blocked arteries to extremities improved by new angioplasty procedure

Patients with blocked arteries to their extremities, known as peripheral artery disease (PAD) or critical limb ischemia (CLI), may now find relief from lower leg pain and wounds caused by impaired leg artery circulation with the previously unproven therapy, percutaneous transluminal angioplasty (PTA).

24 Jul 2012

First results from community HIV testing campaign in Uganda

A clinical study in a remote region of southwest Uganda has demonstrated the feasibility of using a health campaign to rapidly test a community for HIV and simultaneously offer prevention and diagnosis for a variety of other diseases in rural and resource-poor settings of sub-Saharan Africa.

24 Jul 2012

New FDA guidelines on HIV And TB drug doses may not apply to African and Asian patients

In January, 2012, the U.S. Food and Drug Administration (FDA) issued new guidelines on dosing of an HIV medication used to treat people infected with both HIV and tuberculosis (TB) because of a potential interaction between two of the main drugs used to treat each disease.

24 Jul 2012

Michigan High School Athletic Association, U-M collaborate to offer free concussion education

Required online rules meetings for Michigan high school coaches this fall will include a concussion education module from U-M's Michigan NeuroSport and Pediatric Trauma Program at C.S. Mott Children's Hospital.

24 Jul 2012

NIDA announces recipients of 2012 Avant-Garde Award for HIV/AIDS Research

The National Institute on Drug Abuse (NIDA), part of the National Institutes of Health, today announced the recipients of the 2012 Avant-Garde Award for HIV/AIDS Research. The three scientists, Drs. David Smith, Samuel Friedman and Jeremy Luban, will each receive $500,000 per year for five years to support their research.

24 Jul 2012

Implementing population level changes could avoid up to 50% of deaths from CVD

Up to 50% of deaths from cardiovascular disease in Europe could be avoided by implementing population level changes such as taxation and regulation of advertising. Population level prevention will produce greater impacts on CVD than individualised approaches, according to the European Association for Cardiovascular Prevention & Rehabilitation (EACPR) of the European Society of Cardiology (ESC).

24 Jul 2012

Anti-IL-3 monoclonal antibodies to treat early stage Rheumatoid Arthritis in development

SuppreMol GmbH, an autoimmune disease specialist, today announced a licensing agreement with the University Hospital of Regensburg to develop SM401, a humanized anti-IL-3 monoclonal antibody for early diagnosis and treatment of Rheumatoid Arthritis (RA). SuppreMol will advance preclinical development of SM401 for treatment of RA. Simultaneously, the Company will further validate a highly sensitive human IL-3 diagnostic assay for patient stratification.

24 Jul 2012

Rep. Burgess offers bill to extend Medicare doc pay another year; House panel approves more pediatric residencies

The measure on Medicare reimbursements to physicians would put off a dramatic rate cut scheduled to take effect next year.

24 Jul 2012

AIDS medical textbook designed specifically for patients and doctors in resource-poor regions

Warner C. Greene, MD, who directs virology and immunology research at the Gladstone Institutes, has joined with other global AIDS experts to release a locally affordable version of the world's leading AIDS medical textbook. Designed specifically for regions that today are hardest hit by the disease, this new text is the latest weapon in a growing arsenal aimed at curbing the spread of HIV/AIDS worldwide.

24 Jul 2012

Education News and Research

New NIAID grant to support development of topical microbicide gel for HIV and HSV-2 infections

Bill Gates stresses importance of investment in both HIV treatment and research for vaccines, microbicides

Moderate-to-severe TBI can disrupt proteins that regulate enzyme associated with Alzheimer's

Vanderbilt researchers receives new $2.1M grant to develop microbrain bioreactor

Deep look into how brain mechanisms for memory retrieval differ between adults and children

New algorithm can help scientists predict gene and drug interactions

Insight into possible new approaches in vaccine development for blood-borne infections and HIV

Researchers plan to develop new rehabilitation tool for stroke victims

New classification scheme for psychiatric symptoms

Colonoscopy with polypectomy decreases colorectal cancer incidence and mortality

N.J. Dental School receives HSS grant to address nationwide shortage of faculty

Blood flow in blocked arteries to extremities improved by new angioplasty procedure

First results from community HIV testing campaign in Uganda

New FDA guidelines on HIV And TB drug doses may not apply to African and Asian patients

Michigan High School Athletic Association, U-M collaborate to offer free concussion education

NIDA announces recipients of 2012 Avant-Garde Award for HIV/AIDS Research

Implementing population level changes could avoid up to 50% of deaths from CVD

Anti-IL-3 monoclonal antibodies to treat early stage Rheumatoid Arthritis in development

Rep. Burgess offers bill to extend Medicare doc pay another year; House panel approves more pediatric residencies

AIDS medical textbook designed specifically for patients and doctors in resource-poor regions

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