Extensively drug-resistant tuberculosis (XDR TB) is a relatively rare type of multidrug-resistant tuberculosis (MDR TB). It is resistant to almost all drugs used to treat TB, including the two best first-line drugs: isoniazid and rifampin. XDR TB is also resistant to the best second-line medications: fluoroquinolones and at least one of three injectable drugs (i.e., amikacin, kanamycin, or capreomycin).
Because XDR TB is resistant to the most powerful first-line and second-line drugs, patients are left with treatment options that are much less effective and often have worse treatment outcomes.
XDR TB is of special concern for persons with HIV infection or other conditions that can weaken the immune system. These persons are more likely to develop TB disease once they are infected, and also have a higher risk of death once they develop TB disease.
The risk of acquiring XDR TB in the United States appears to be relatively low. However, it is important to acknowledge the ease at which TB can spread. As long as XDR TB exists, the United States is at risk and must address the threat.
The World Health Organization, Stop TB Partnership, UNITAID and the Foundation for Innovative New Diagnostics on Monday announced a joint project to distribute a new diagnostic test for multi-drug resistant tuberculosis that can produce results in two days instead of the standard two or three months, the New York Times reports. Difficulty in identifying MDR-TB has been a "major obstacle" in controlling TB because many patients die or spread the disease while waiting for test results, the Times reports.
Researchers have developed a new test which can quickly detect multi drug-resistant tuberculosis (MDR-TB).
A leading Australian expert has warned that the international attention devoted to HIV/AIDS has dwarfed the threat of tuberculosis (TB).
Health officials in Britain say they are dealing with the country's first case of a rare strain of tuberculosis (TB) which is almost untreatable.
Multidrug-resistant tuberculosis (MDR-TB) has been recorded at the highest rates ever, according to a new report published today.
A new World Bank research report finds that 22 countries with the world's highest numbers of TB cases could earn significantly more than they spend on TB diagnosis and treatment if they signed onto a global plan to sharply reduce the numbers of TB-related deaths.
An international collaboration led by researchers in the US and South Africa today announced the first genome sequence of an extensively drug resistant (XDR) strain of the bacterium Mycobacterium tuberculosis, one linked to more than 50 deaths in a recent tuberculosis (TB) outbreak in KwaZulu-Natal, South Africa.
More than at any previous time in history, global public health security depends on international cooperation and the willingness of all countries to act effectively in tackling new and emerging threats.
The World Health Organisation (WHO) has warned the world to expect a new killer disease to emerge in the next few years which will threaten the lives of millions.
It seems the jet setting air traveller with tuberculosis (TB) is not quite as dangerous as first thought. According to a federal health official, American lawyer Andrew Speaker has a less severe form of TB than previously diagnosed.
According to the World Health Organization (WHO) some forms of tuberculosis (TB) are a threat to the security and stability of global health.
Hundreds of thousands of cases of drug-resistant tuberculosis (TB) can be prevented and as many as 134 000 lives saved through the implementation of a two-year response plan, published/launched today by the World Health Organization (WHO) and the Stop TB Partnership.
The National Institute of Allergy and Infectious Diseases (NIAID), a component of the National Institutes of Health (NIH), has released its NIAID Research Agenda for Multidrug-Resistant (MDR) and Extensively Drug-Resistant (XDR) Tuberculosis (TB).
In the case of the jet flying traveler with TB a great deal of criticism has been leveled at U.S. authorities.
Marc Hiller, associate professor of health management and policy at the University of New Hampshire and a specialist in ethical issues in public health, is available to comment on the recent federal order that placed a Georgia man with a lethal form of tuberculosis into quarantine.
The Centers for Disease Control and Prevention (CDC) in the United States have placed a trans-Atlantic air traveler under quarantine because he has a rare and dangerous form of tuberculosis.
Securing its place as an indispensable defence against the development and spread of drug-resistant tuberculosis (TB), the Stop TB Partnership announced that its drug supply arm, the Global Drug Facility, has provided anti-TB drug treatments for 10 million people to 78 countries in the past six years.
Extremely drug resistant TB, or XDR-TB, is a serious problem in India, according to a study presented at the American Thoracic Society 2007 International Conference, on Monday, May 21.
Access to antiretroviral therapy for advanced HIV infection in low- and middle-income countries continued to grow throughout 2006, with more than 2 million people living with HIV/AIDS receiving treatment in December 2006, a 54% increase over the 1.3 million people on treatment one year earlier in these countries.
Lesotho is "struggling to contain" the spread of tuberculosis in the face of its HIV/AIDS epidemic, IRIN News reports. In 2006, the country reported 12,000 new TB cases, but TB expert Peter Saranchuk of Medecins Sans Frontieres said the actual number of cases likely is much higher.
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