Therapeutics News and Research

RSS

Innovative microneedle patch shows promise in treating alopecia areata

Alopecia areata (AA) is an autoimmune disease characterized by hair loss, which occurs when T cells of the immune system mistakenly attack hair follicles.

6 Jun 2024

New molecular portrait of KRAS in pancreatic cancer may guide better treatments

Researchers at UNC Lineberger Comprehensive Cancer Center and colleagues have established the most comprehensive molecular portrait of the workings of KRAS, a key cancer-causing gene or "oncogene," and how its activities impact pancreatic cancer outcomes.

6 Jun 2024

Discovery paves the way for more specific cancer drugs with fewer side effects

The small protein ubiquitin is involved in almost every cellular process in our body: it orchestrates the stability and function of the vast majority of proteins.

6 Jun 2024

Columbia scientists uncover true identity of gut's hardworking stem cells

Two independent studies by Columbia scientists suggest that research into the gut's stem cells over the past 15 years has been marred by a case of mistaken identity: Scientists have been studying the wrong cell.

6 Jun 2024

AI-powered liquid biopsy shows promise in early detection of lung cancer

Using artificial intelligence technology to identify patterns of DNA fragments associated with lung cancer, researchers from the Johns Hopkins Kimmel Cancer Center and other institutions have developed and validated a liquid biopsy that may help identify lung cancer earlier.

6 Jun 2024

Ultrasound technology breaks blood-brain barrier for glioblastoma treatment

In a major advance for the treatment of the deadly brain cancer glioblastoma, Northwestern Medicine scientists used ultrasound technology to penetrate the blood-brain barrier and provide a small dose of a chemotherapy and immunotherapy drug cocktail.

6 Jun 2024

Higher amounts of sugar alcohol xylitol associated with increased risk of cardiovascular events

Cleveland Clinic researchers found higher amounts of the sugar alcohol xylitol are associated with increased risk of cardiovascular events like heart attack and stroke.

6 Jun 2024

Increasing levels of key protein may prevent macular degeneration progression

Increasing the levels of a key protein in the cells at the back of the eye could help protect against the leading cause of vision loss among older adults, finds a new discovery made by researchers from the UK, US, Germany and Australia.

5 Jun 2024

In utero brain overgrowth linked to severity of autism

Some children with autism experience profound, lifelong difficulties like developmental delay, social struggles and even the inability to speak.

5 Jun 2024

Targeting TGFβ/ROCK2/YAP signaling axis to enhance drug delivery in fibrotic pancreatic cancer

Pancreatic cancer, recognized as one of the deadliest cancers, poses a persistent challenge for medical professionals globally due to its aggressive behavior and resistance to conventional therapies.

5 Jun 2024

New bilateral gene therapy shows promising results in treating genetic hearing loss

A novel gene therapy designed to target a form of inherited deafness restored hearing function in five children who were treated in both ears.

5 Jun 2024

Salk researchers unveil SWI/SNF variants' role in macrophage immune responses

Bacteria, parasites, viruses-;the immune system tackles them all. At the front line of the human immune response are cells called macrophages, which are responsible for correctly identifying intruders and then directing how the entire immune system responds.

5 Jun 2024

Insomnia linked to higher ovarian cancer risk and mortality in new genetic study

Researchers found a significant genetic link between insomnia and increased risk and mortality in epithelial ovarian cancer (EOC).

4 Jun 2024

Unraveling the mechanisms of PMP22 duplication in Charcot-Marie-Tooth disease

Charcot-Marie-Tooth disease (CMT), a group of heritable disorders that affect the peripheral nerves, is marked by specific genetic changes.

4 Jun 2024

Low-dose aspirin can reduce inflammatory responses to sleep restriction

A new study to be presented at the SLEEP 2024 annual meeting found that low-dose acetylsalicylic acid, also known as aspirin, can reduce inflammatory responses to sleep restriction.

3 Jun 2024

Experimental treatment for metastatic pancreatic cancer shows promise in phase 2 clinical trial

Clinicians at Georgetown University's Lombardi Comprehensive Cancer Center reported promising preliminary findings based on outcomes in the first six patients with metastatic pancreatic cancer enrolled in a phase 2 clinical trial of the experimental drug BXCL701 in combination with the immunotherapy drug pembrolizumab (Keytruda).

3 Jun 2024

US DoD funds Australian research on Parkinson's disease treatments

Researchers based at Australia’s Translational Research Institute (TRI) have received major funding from the United States Department of Defense (DoD) to develop Parkinson’s disease (PD) treatments by targeting the gut microbiome.

3 Jun 2024

Foam technology revolutionizes gene therapy, boosting efficiency and safety

Liquid foam gene delivery significantly enhances transfection efficiency and safety, offering a cost-effective alternative to conventional methods.

3 Jun 2024

Intermittent fasting with protein pacing trumps calorie restriction in gut health and weight loss

A recent study in Nature Communications found that intermittent fasting with protein pacing (IF-P) is more effective than continuous calorie restriction (CR) in improving gut microbiota and metabolomic profiles, leading to greater weight and fat loss.

2 Jun 2024

Breakthrough CAR T therapy and shorter targeted therapy durations offer hope for patients with leukemia

The novel anti-CD19 autologous chimeric antigen receptor (CAR) T cell therapy obecabtagene autoleucel (obe-cel) achieved durable remissions in 40% of patients with relapsed or refractory B-ALL without a subsequent stem cell transplant (SCT), according to results from the Phase Ib/II FELIX clinical trial presented today by Elias Jabbour, M.D., professor of Leukemia.

31 May 2024

Therapeutics News and Research

Innovative microneedle patch shows promise in treating alopecia areata

New molecular portrait of KRAS in pancreatic cancer may guide better treatments

Discovery paves the way for more specific cancer drugs with fewer side effects

Columbia scientists uncover true identity of gut's hardworking stem cells

AI-powered liquid biopsy shows promise in early detection of lung cancer

Ultrasound technology breaks blood-brain barrier for glioblastoma treatment

Higher amounts of sugar alcohol xylitol associated with increased risk of cardiovascular events

Increasing levels of key protein may prevent macular degeneration progression

In utero brain overgrowth linked to severity of autism

Targeting TGFβ/ROCK2/YAP signaling axis to enhance drug delivery in fibrotic pancreatic cancer

New bilateral gene therapy shows promising results in treating genetic hearing loss

Salk researchers unveil SWI/SNF variants' role in macrophage immune responses

Insomnia linked to higher ovarian cancer risk and mortality in new genetic study

Unraveling the mechanisms of PMP22 duplication in Charcot-Marie-Tooth disease

Low-dose aspirin can reduce inflammatory responses to sleep restriction

Experimental treatment for metastatic pancreatic cancer shows promise in phase 2 clinical trial

US DoD funds Australian research on Parkinson's disease treatments

Foam technology revolutionizes gene therapy, boosting efficiency and safety

Intermittent fasting with protein pacing trumps calorie restriction in gut health and weight loss

Breakthrough CAR T therapy and shorter targeted therapy durations offer hope for patients with leukemia

Revolutionizing Life Science: An Interview with SCIEX on ASMS, the SCIEX 7500+ System, and AI-Driven Quantitation

From Discovery Biology to ELRIG Chair

Breathing New Life into Diagnostics: Plasmion's SICRIT Technology

Latest News