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Positive results from Repligen's RG3039 Phase 1 study for spinal muscular atrophy

Repligen Corporation today announced positive results from a Phase 1 study to evaluate the pharmacokinetic (PK) and safety profile of RG3039, a novel small molecule drug candidate for the potential treatment of spinal muscular atrophy (SMA).

25 Apr 2012

Omega-3 supplements do not improve diastolic function in older adults

Over the past three decades, researchers have firmly established that the omega-3 fatty acids in fish oil, including eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), have healthy effects on the heart. Omega-3 fatty acids seem to help both in preventing cardiovascular disease as well as in preventing future heart attacks, strokes, and other adverse events in people who have established cardiovascular disease.

25 Apr 2012

Sheffield researchers investigate ways to improve treatment for elderly patients with breast cancer

Sheffield researchers are investigating ways to improve the treatment and survival rate of elderly patients diagnosed with breast cancer.

25 Apr 2012

Providers can and should work toward 'sustainable anesthesia'

Anesthesia providers can and should begin taking steps toward practicing "sustainable anesthesia," according to the May special issue of Anesthesia & Analgesia, official journal of the International Anesthesia Research Society.

25 Apr 2012

MMP-10 gene plays a dual role in lung cancer

A single gene that promotes initial development of the most common form of lung cancer and its lethal metastases has been identified by researchers at Mayo Clinic in Florida.

25 Apr 2012

Book aims to improve overall cardiovascular health of its readers

Dr. Antonio M. Gotto Jr., dean emeritus and co-chairman of the board of overseers at Weill Cornell Medical College, is the co-author of a new book called The Living Heart in the 21st Century. The book, a new edition in The Living Heart best-selling series, is the essential resource guide for patients about cardiovascular disease prevention and treatment.

25 Apr 2012

Globe and Mail profiles former President Jimmy Carter, Carter Center's efforts to eradiacate guinea worm

The Globe and Mail profiles former President Jimmy Carter and the Carter Center's decades-long efforts to eradicate guinea worm disease, also known as dracunculiasis. According to the newspaper, "In 2011, there were 1,060 cases of guinea worm disease identified in the world, in four countries," and "staff and volunteers from the Carter Center have visited every one of the 26,500 villages where guinea worm was identified" to provide education on prevention, as well as treatment.

25 Apr 2012

CAM therapies plus usual care can improve outcomes in low back pain patients

Nearly 8 of 10 Americans will experience lower back pain at some time in their lives. Persistent low back pain is a common, incapacitating, costly, and difficult to treat condition. Many patients might benefit significantly from an individualized, multidisciplinary, team-based model of care that includes access to licensed complementary care practitioners addition to conventional care providers, as demonstrated in a study published in The Journal of Alternative and Complementary Medicine, a peer-reviewed journal from Mary Ann Liebert, Inc.

25 Apr 2012

S-equol effective in reducing menopausal hot flashes, muscle and joint pain among U.S. women

A dose of 10 milligrams (mg) daily of S-equol delivered via a newly developed fermented soy germ-based nutritional supplement is as effective as a standard dose of soy isoflavones at reducing hot flash frequency significantly and is even more effective for relieving muscle and joint pain, according to a peer-reviewed study in US postmenopausal women published in the June Journal of Women's Health, available now as a Fast Track article online ahead of print.

25 Apr 2012

ASH report urges federal agencies to invest in 7 distinct areas of research

The American Society of Hematology (ASH), the world's largest professional society committed to the study and treatment of blood disorders, today issued a report urging federal agencies to coordinate hematology research funding around seven specific high-need areas that would produce the greatest impact and translate into improvements in patient care in the United States.

25 Apr 2012

ATA to honor Loyola pediatrician for contributions in the field of telemedicine

Loyola University Medical Center pediatrician Dr. Kathleen Webster, a leader in the growing field of telemedicine, is being honored by the American Telemedicine Association.

25 Apr 2012

AANF changes name to American Brain Foundation

The American Academy of Neurology Foundation is now the American Brain Foundation. The name change is part of an overall re-branding campaign as the organization repositions itself to become the world's leader in raising money for research to cure brain diseases, such as Alzheimer's disease, stroke, Parkinson's disease, autism, and epilepsy.

25 Apr 2012

Weakened malaria control programs linked to majority of global resurgences

Funding cuts for malaria control are the single most common reason for the resurgence of the deadly disease, according to a new study that has linked overall weakened malaria control programs to the majority of global resurgences since 1930.

25 Apr 2012

Impaired mitochondrial function may play a major role in mood and psychotic disorders

Janssen Research & Development, LLC announced today the publication of an article that reviews the growing evidence that impaired mitochondrial function may play a major role in mood and psychotic disorders.

25 Apr 2012

Dark chocolate may reduce risk of cardiovascular disease

Chocolate, considered by some to be the "food of the gods," has been part of the human diet for at least 4,000 years; its origin thought to be in the region surrounding the Amazon basin. Introduced to the Western world by Christopher Columbus after his fourth voyage to the New World in 1502, chocolate is now enjoyed worldwide. Researchers estimate that the typical American consumes over 10 pounds of chocolate annually, with those living on the west coast eating the most. Wouldn't it be great if only chocolate were considered healthy?

25 Apr 2012

Fish oil supplementation may effectively reduce periodontal symptoms

Periodontitis, inflammation of the tissue surrounding the teeth, affects more than half of adults and is linked to an increased risk of stroke and other heart problems. To evaluate whether fish oil supplementation could be an adjunct therapy for periodontitis, Dr. Alison Coates from the University of South Australia and colleagues from the School of Dentistry at University of Adelaide in Australia reviewed evidence from eight unique studies that involved humans.

25 Apr 2012

Louisiana Tech professor receives NSF CAREER grant

Dr. Niel Crews, assistant professor of mechanical engineering at Louisiana Tech University and a member of Tech's Institute for Micromanufacturing, has been awarded an Early Career Development grant by the National Science Foundation (NSF) for his proposal, "Thermal Gradient Microflow Calorimetry using Anisotropic Temperature Sensors."

25 Apr 2012

PET/CT could help improve prediction of heart attack

An award-winning research project, funded by the British Heart Foundation (BHF), has tested a new imaging method which could help improve how doctors predict a patient's risk of having a heart attack.

25 Apr 2012

AMSSM researcher discusses genetic associations with concussions

Thomas R. Terrell, MD presented "Prospective Cohort Study of the Association of Genetic Polymorphisms and Concussion Risk and Postconcussion Neurocognitive Deficits in College Athletes" at the 21st American Medical Society for Sports Medicine Annual Meeting in Atlanta, Ga. on April 23, 2012.

25 Apr 2012

U of O introduces Refugees and Global Health online program in Canada

All Canadian medical students, residents and practitioners now have full access to an innovative Web-based tool to enhance their understanding of medical care for refugees and new Canadians.

25 Apr 2012