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New project aims to gain insights into bone metastasis in breast cancer patients

A new project just launched at Karl Landsteiner University of Health Sciences in Krems aims at gaining insights into the development of bone metastases in breast cancer patients and identifying biomarkers as well as new treatment strategies.

20 Feb 2020

First baby born from frozen immature eggs matured in the lab

Cancer can take a toll on a woman’s body, with many unable to conceive after rigorous treatments. In some cases, especially for women who have no children yet, they opt for egg cell freezing so they can still become pregnant after treatment. Now, for the first time, a woman has given birth to a baby from frozen immature eggs harvested from her five years ago.

19 Feb 2020

Pancreatic cancer 'time machine' reveals tumor development and invasion

Pancreatic cancer has one of the worst survival rates among cancers. Patients can expect as low as a 9% chance to live for at least five years after being diagnosed.

18 Feb 2020

First transplant of deceased donor's uterus in Sweden

The Swedish team responsible for uterine transplantation research has, for the first time, transplanted a uterus from a deceased donor. The operation proceeded without complications and the recipient is doing well.

18 Feb 2020

New 3D model shows how breast cancer cells interact with the body’s stem cells

A Loughborough University Ph.D. student has provided new insight into how breast cancer cells interact with cells in our body by using a novel 3D model.

18 Feb 2020

Bruker announces fully validated NMR module for metabolite quantification in urine (research use only)

Bruker has announced the release of the B.I.QUANT-UR™ 1.1 module, which complies with DIN-ISO criteria for the quantification of urine metabolites by NMR.

From Bruker BioSpin Group 18 Feb 2020

Slightly increased risk of death for babies conceived by IVF

A new study published in the journal Fertility and Sterility in February 2020 reports a higher risk for mortality in children who were conceived by the in vitro fertilization (IVF) technique followed by freezing of the embryos, compared to those naturally conceived, but only in the first few weeks of life.

18 Feb 2020

Scientists create world’s first model of pituitary disease using human iPS cells

Researchers at Kobe University's Graduate School of Medicine have developed the world's first congenital pituitary hypoplasia model using patient-derived iPS cells.

14 Feb 2020

Discovery of compound that reverses the fertility clock

The reproductive years of a woman are at their peak before the age of 30. Beyond that, fertility starts to decline, and by the age of 40, fertility potential is about half the level it was before 30 years old. Many women experience fertility issues, but now a new study on mice may help reverse the clock on eggs, offering new fertility hope to older women.

13 Feb 2020

Study tests hypothesis that empty SV40 capsids would improve sepsis outcomes

Numerous previous attempts to develop therapeutic treatments, directed at discreet targets of the sepsis cascade, could not cope with the complex pathophysiology of sepsis and failed.

13 Feb 2020

Bacterial viruses in intestinal tracts of children may play a role in stunting

New research spearheaded by McGill University has discovered that bacteriophages (viruses that infect bacteria) found in the intestinal tracts of children may play a role in childhood stunting, a significant impediment to growth that affects 22% of children under the age of five around the world.

12 Feb 2020

Bacterial DNA promotes tau protein misfolding and aggregation, study shows

Researchers from Human Microbiology Institute and Mitchell Center for Alzheimer’s disease at the University of Texas McGovern Medical School in Houston have discovered that bacterial extracellular DNA can trigger Tau protein misfolding into neurotoxic aggregates, a key process in Alzheimer’s disease pathogenesis.

12 Feb 2020

Pioneering project on genomic edition through CRISPR/Cas9 to study early embryonic development

Characterization studies of early embryonic development are limited, mainly due to the lack of samples and the obvious legal and ethical limitations.

11 Feb 2020

Novel melatonin receptor molecules potentially address circadian rhythm disturbances

Like breathing or blinking, behaviors regulated by our circadian rhythms, such as digestion and sleep-wake cycles, go unnoticed by most people.

10 Feb 2020

Study explores how some mammals postpone development of their embryos

How do some mammals postpone the development of their embryos to await better conditions for having offspring? A recent study at the UW Medicine Institute for Stem Cell and Regenerative Medicine explored this reproductive enigma, which can occur in more than 130 species of mammals as well as in some marsupials.

10 Feb 2020

New method to treat cancer with iron oxide nanoparticles

The concept is based on the interaction of resonant semiconductor iron oxide Fe2O3 nanoparticles with light. Particles previously loaded with the antitumor drug are injected in vivo and further accumulate at the tumor areas.

10 Feb 2020

Novel innate immunity factor inhibits HIV infection by targeting lipid rafts, study finds

The human protein apolipoprotein A-I binding protein inhibits HIV replication by targeting lipid rafts and reducing virus-cell fusion, according to a new study published in the premier American Society for Microbiology journal mBio by researchers from the George Washington University.

10 Feb 2020

Growing eggs and sperm to treat infertility

Scientists at the University of California, Los Angeles, have reported, in the journal Cell Reports, the mechanism of how the very early precursor or stem cells which eventually give rise to the germ cells, eggs and sperm, are formed over the course of development. This could help create eggs and sperms under laboratory conditions to help infertile people who don’t have sperms, or eggs, for instance.

9 Feb 2020

New study sheds light on human in vitro organ model research trends

Two distinct approaches are predominantly used to recapitulate physiologically relevant in vitro human organ models.

9 Feb 2020

Researchers develop new substance to prevent vascular calcification

Researchers at ETH Zurich and ETH spin-off Inositec have developed a new substance to prevent vascular calcification, which affects many patients suffering from chronic kidney disease.

5 Feb 2020