in vitro News and Research

RSS

Researchers discover molecular underpinnings of Alexander disease

Scientists have known that genetic mutations leading to the production of a defective protein called GFAP cause Alexander disease (AxD), a debilitating neurodegenerative condition that can present during infancy, adolescence, or adulthood.

21 Nov 2019

Subpopulations of tumor cells may exhibit diverging behaviors from bulk tumor

Subpopulations of tumor cells may exhibit diverging behaviors from the bulk tumor due to an alternate stress response that diverts tumor cells from apoptotic death.

20 Nov 2019

New database helps identify therapeutic targets to fight infectious diseases

Infectious diseases are caused by pathogenic microorganisms capable of entering, colonizing and growing within a host organism, thus producing an infection. Bacterial infections have been on the rise worldwide in recent years, but many mechanisms underlying bacterial pathogenesis are still poorly understood.

19 Nov 2019

Research findings can be used in antiviral development against enterovirus infections

Despite their prevalence, there are no antivirals on the market against enteroviruses, and vaccines have been developed only against couple of serotypes. The production of vaccines against all enterovirus serotypes is not feasible, and so antiviral drugs may be the solution for most of the enterovirus infections.

19 Nov 2019

CTF, DELopen jointly offer unique opportunities to neurofibromatosis research community

The Children's Tumor Foundation, an innovative and global neurofibromatosis (NF) research foundation announced today a collaboration with DELopen, a DNA-encoded library technology platform sponsored by WuXi AppTec, a leading global provider of R&D and manufacturing services enabling companies in the pharmaceutical, biotechnology and medical device industries.

19 Nov 2019

TARA's organ-on-a-chip technology can directly measure in vivo cardiac performance, study shows

TARA Biosystems, Inc. today reported in vivo and in vitro functional data from a study of investigational candidate, MYK-491, showing that TARA's human iPSC-derived organ-on-a-chip technology can directly measure in vivo cardiac performance.

18 Nov 2019

Study: 15,000 cases of hypophosphatasia potentially undetected in Spanish population

Hypophosphatasia (HPP) is a rare and serious hereditary disease that is potentially life-threatening and is caused by one or more mutations in the gene coding for alkaline phosphatase (ALPL). It is frequently misdiagnosed.

15 Nov 2019

Blocking a molecule could delay the progression of multiple sclerosis

Over 77,000 Canadians are living with multiple sclerosis, a disease whose causes still remain unknown. Presently, they have no hope for a cure.

14 Nov 2019

Turbine secures institutional financing of €3m to expand potential of simulation-first drug discovery

Turbine, a simulation-based drug discovery company today announced the closing of an institutional financing round led by Delin Ventures.

From Turbine Simulated Cell Technologies Ltd. 14 Nov 2019

Clinical analysis reveals high expression of apoptosis protein in chemoresistant TNBC

78 TNBC biopsies from patients with different responses to chemotherapy were analysed for API-5 expression before any treatment.

13 Nov 2019

Study offers significant contribution for recovery of motor functions

Delivering a diversified electric message to the different fibres of the injured spinal cord through a new technology able to deliver it in a targeted and independent manner. What is the result? Greater efficiency in recovering the control of voluntary limb movements in the event of serious damage to the spinal cord.

13 Nov 2019

U-M's insurance coverage benefit associated with increase in IVF rates

For couples wanting to have a baby, a diagnosis of infertility can be devastating. And while infertility treatments, such as in vitro fertilization (IVF), offer hope for would-be parents, the procedure comes with a high price tag.

13 Nov 2019

Fertilization discovery reveals egg's role, potentially paves way for new contraceptive

An unexpected discovery about fertilization from the University of Virginia School of Medicine reveals new insights on how sperm and egg fuse and could have major implications for couples battling infertility – and may lead to a future male contraceptive.

13 Nov 2019

Virginia Tech professor wins $1.85 million NIH grant for sepsis research

One drop of blood contains 5,000 neutrophils, the most abundant type of white blood cell that is deployed by the human immune system. Throughout the entire body, a human has 25 billion of these foot soldiers that are relentlessly patrolling to fight invading pathogens.

12 Nov 2019

Promega and Merck collaborate to develop MSI companion diagnostic for use with anti-PD-1 therapy

Promega Corporation today announced it has entered into a global collaboration with Merck, to develop Promega’s microsatellite instability technology.

From Promega Corporation 8 Nov 2019

National effort to develop implantable bio-artificial kidney achieves key milestone

The Kidney Project, a national effort to develop an implantable bio-artificial kidney that could eliminate the need for dialysis, will announce a key milestone in a November 7, 2019 presentation at the American Society of Nephrology Kidney Week 2019 conference in Washington, DC.

7 Nov 2019

ISPOR explores the evolving demands for evidence requirements relating to medical devices

ISPOR, the professional society for health economics and outcomes research - explored the issue of medical devices and the evolving demands for evidence requirements and assessments in the session, "The Evolving Demands for Medical Device Evidence Development: What the Future Holds." [SP3]. The session was held this afternoon at ISPOR Europe 2019 in Copenhagen, Denmark.

6 Nov 2019

Mosaicism of IVF embryos does not pose any health risks to future babies

Compared to the mother's body, the egg fertilized in a test tube has rather different conditions for growing.

5 Nov 2019

Humanizing cell cultures

Today we know the function and metabolism of any mammalian cell depends on its environment. Such cells have long been cultured under conditions consisting of a basal medium with added nutritional serum. This, however, is not an accurate replica of the cell’s environment within the human body.

5 Nov 2019

Increasing anti-tumor activity of compound extracted from an Amazon plant

Researchers in Brazil have prepared modified forms of the alkaloids produced by Uncaria guianensis, a woody vine native to the Amazon Rainforest.

31 Oct 2019

in vitro News and Research

Researchers discover molecular underpinnings of Alexander disease

Subpopulations of tumor cells may exhibit diverging behaviors from bulk tumor

New database helps identify therapeutic targets to fight infectious diseases

Research findings can be used in antiviral development against enterovirus infections

CTF, DELopen jointly offer unique opportunities to neurofibromatosis research community

TARA's organ-on-a-chip technology can directly measure in vivo cardiac performance, study shows

Study: 15,000 cases of hypophosphatasia potentially undetected in Spanish population

Blocking a molecule could delay the progression of multiple sclerosis

Turbine secures institutional financing of €3m to expand potential of simulation-first drug discovery

Clinical analysis reveals high expression of apoptosis protein in chemoresistant TNBC

Study offers significant contribution for recovery of motor functions

U-M's insurance coverage benefit associated with increase in IVF rates

Fertilization discovery reveals egg's role, potentially paves way for new contraceptive

Virginia Tech professor wins $1.85 million NIH grant for sepsis research

Promega and Merck collaborate to develop MSI companion diagnostic for use with anti-PD-1 therapy

National effort to develop implantable bio-artificial kidney achieves key milestone

ISPOR explores the evolving demands for evidence requirements relating to medical devices

Mosaicism of IVF embryos does not pose any health risks to future babies

Humanizing cell cultures

Increasing anti-tumor activity of compound extracted from an Amazon plant

eBook: Using iPSCs models for human disease research and drug discovery eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Latest News