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Study examines role of plastic exposure in irregular heart rhythms, arrhythmias

Calling an ambulance during an emergency, emailing a breaking news or journal article before a 5 p.m. deadline and maintaining conditions during the fifth week of a 6-week lab study, without altering the light or temperature, requires electricity and translates into time, money and lives

22 Jul 2019

Receptor in the uterus can detect sperm molecule, aids in sperm survival

Why does it take 200 million sperms to fertilize a single egg? The single sperm that reached the finished line has successfully survived multiple checkpoints within the female reproductive tract, dubbed as pre-fertilization events. Now, a new study shows that the uterus contains receptors that facilitate sperm survival.

19 Jul 2019

Oxidative stress could play key role in the spreading of aberrant proteins in Parkinson's disease

Oxidative stress could be a driving force in the spreading of aberrant proteins involved in Parkinson's disease.

17 Jul 2019

FDA approves antibacterial drug to treat complicated urinary tract infections, intra-abdominal infections

The U.S. Food and Drug Administration has approved Recarbrio (imipenem, cilastatin and relebactam), an antibacterial drug product to treat adults with complicated urinary tract infections (cUTI) and complicated intra-abdominal infections (cIAI).

17 Jul 2019

Research opens possibility of developing single-dose gene therapy for inherited arrhythmias

Researchers at Boston Children's Hospital report creating the first human tissue model of an inherited heart arrhythmia, replicating two patients' abnormal heart rhythms in a dish, and then suppressing the arrhythmia with gene therapy in a mouse model.

17 Jul 2019

HbA1c analyzer identifies diabetics with poor glycemic control and high risk of sight loss

This HbA1c analyzer is successfully supporting improved medical management of patients with sight-threatening diabetic retinopathy (STDR).

From EKF Diagnostics 16 Jul 2019

Human pancreas on a chip could help identify possible cause of CF-Related Diabetes

Scientists created human pancreas on a chip that allowed them to identify the possible cause of a frequent and deadly complication of cystic fibrosis (CF) called CF-Related Diabetes, or CFRD.

16 Jul 2019

Evaluating safety and efficacy of magnetically labeled mesenchymal stem cells

Cells equipped with superparamagnetic iron oxide nanoparticles can be directed to a specific location by an external magnetic field, which is beneficial for tissue repair.

16 Jul 2019

Veravas launches advanced solutions to address biotin interference in diagnostic tests

Veravas, Inc., an emerging diagnostic company, launched a portfolio of products that can improve the accuracy of current diagnostic test results by helping laboratory professionals detect and manage biotin interference in patient samples with VeraTest Biotin and VeraPrep Biotin.

12 Jul 2019

Tomocube HT microscope enables label-free quantification of cellular lipid content

In a breakthrough for research fields as diverse as diabetes, atherosclerosis and biofuels, the mass, concentration, volume, and surface area of individual lipid droplets have been measured in live, unstained cells for the first time using a Tomocube Holotomography microscope.

From Tomocube Inc. 12 Jul 2019

New study reveals 'clutch' proteins responsible for putting T cell activation 'into gear'

In collaborative research, scientists from three continents were able to discover a crucial bit of information about how T cells move proteins inside them to drive the immune response. This could help evolve specific new treatments centered on T cell selectivity.

12 Jul 2019

Sorting protein in neurons protects against neurodegenerative disorders

Like a sorting machine in an assembly line, a molecule known as VPS35 detects and removes defective proteins from neurons.

10 Jul 2019

HER2-positive breast cancer may be treated with imprinted nanospheres

A particularly aggressive, metastasizing form of cancer, HER2-positive breast cancer, may be treated with nanoscopic particles “imprinted” with specific binding sites for the receptor molecule HER2.

4 Jul 2019

Researcher finds possible strategy for killing cancer cells in children

In Belgium, there are 70,000 new adult cases of cancer every year, compared to 350 in children. Owing to lack of interest from pharmaceutical groups, treatments for pediatric cancers are developing much less rapidly than those for adults.

4 Jul 2019

Hesperos' multi-organ model correctly determine cardiotoxic mechanisms

Hesperos Inc., pioneers of the "human-on-a-chip" in vitro system has announced the use of its innovative multi-organ model to successfully measure the concentration and metabolism of two known cardiotoxic small molecules over time, to accurately describe the drug behavior and toxic effects in vivo.

4 Jul 2019

Healthy mice pups can be produced from sperm without short RNA chains

Scientists from the University of Bath are challenging the claims of two high profile papers from 2018 which reported that in the mouse, RNA has to be added to sperm for them to be fully fertile.

4 Jul 2019

Promising method delivers drug to cancer cells without affecting surrounding cells

RIKEN researchers have developed a promising method to deliver a drug to cancer cells without affecting surrounding tissues, involving a clever combination of an "artificial metalloenzyme" that protects a metal catalyst, and a sugar chain that guides the metalloenzyme to the desired cells.

2 Jul 2019

New method to grow embryonic stem cells on a microfluidic chip

It's no surprise that using human embryos for biological and medical research comes with many ethical concerns. Correct though it is to proceed with caution in these matters, the fact is that much science would benefit from being able to study human biology more accurately.

29 Jun 2019

Pharmaceutical products made of solid gold

Over the past twenty years, the use of nanoparticles in medicine has steadily increased. However, their safety and effect on the human immune system remains an important concern.

28 Jun 2019

Goat's milk-based formula good for infant's gut health

Researchers from RMIT’s lab analyzed goat’s milk formula and looked at the oligosaccharides present in it.

27 Jun 2019

in vitro News and Research

Study examines role of plastic exposure in irregular heart rhythms, arrhythmias

Receptor in the uterus can detect sperm molecule, aids in sperm survival

Oxidative stress could play key role in the spreading of aberrant proteins in Parkinson's disease

FDA approves antibacterial drug to treat complicated urinary tract infections, intra-abdominal infections

Research opens possibility of developing single-dose gene therapy for inherited arrhythmias

HbA1c analyzer identifies diabetics with poor glycemic control and high risk of sight loss

Human pancreas on a chip could help identify possible cause of CF-Related Diabetes

Evaluating safety and efficacy of magnetically labeled mesenchymal stem cells

Veravas launches advanced solutions to address biotin interference in diagnostic tests

Tomocube HT microscope enables label-free quantification of cellular lipid content

New study reveals 'clutch' proteins responsible for putting T cell activation 'into gear'

Sorting protein in neurons protects against neurodegenerative disorders

HER2-positive breast cancer may be treated with imprinted nanospheres

Researcher finds possible strategy for killing cancer cells in children

Hesperos' multi-organ model correctly determine cardiotoxic mechanisms

Healthy mice pups can be produced from sperm without short RNA chains

Promising method delivers drug to cancer cells without affecting surrounding cells

New method to grow embryonic stem cells on a microfluidic chip

Pharmaceutical products made of solid gold

Goat's milk-based formula good for infant's gut health

Human iPSCs: A Full Guide to Advanced in Vitro Models and Applications eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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