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RAB35 protein plays role in oncogenic process

A protein known to play a role in transporting the molecular contents of normal cells into and out of various intracellular compartments can also turn such cells cancerous by stimulating a key growth-control pathway.

4 Sep 2015

Researchers find intrinsic differences in mice’s neural stem cells using image-tracking technology

One of the longstanding debates in science, that has, perhaps unsurprisingly, permeated into the field of stem cell research, is the question of nature versus nurture influencing development.

4 Sep 2015

Preventing the build up of dangerous biofilms, ESCMID publishes guidelines

The European Society of Clinical Microbiology and Infectious Disease (ESCMID) – an organization that explores the risks and best practices in infectious disease – advocates the need for greater education, guidance and research on the build-up, treatment and prevention of biofilms, which contribute to antimicrobial resistance.

2 Sep 2015

Allergan announces positive results from AVYCAZ Phase III studies for treatment of cUTI

Allergan plc. today announced positive topline results from RECAPTURE 1 and 2, the pivotal Phase III studies evaluating the antibiotic AVYCAZ (ceftazidime-avibactam) as a treatment for adult hospitalized patients with complicated urinary tract infections (cUTI), including pyelonephritis.

2 Sep 2015

Egalet to present scientific data on SPRIX Nasal Spray at Painweek 2015

Egalet Corporation, a fully integrated specialty pharmaceutical company focused on discovering, developing, and commercializing innovative pain treatments, today announced that researchers will be presenting scientific data on SPRIX (ketorolac tromethamine) Nasal Spray, Egalet-001, an abuse-deterrent, extended-release, oral morphine product candidate, and Egalet-002, an abuse-deterrent, extended-release, oral oxycodone product in development, at PainWeek 2015 to be held September 8 to 12 in Las Vegas, Nevada.

1 Sep 2015

Scientists elucidate chemical process behind eosinophilic esophagitis

Scientists from the D'Or Institute of Research and Education, the Federal University of Rio de Janeiro and the Yale University School of Medicine have elucidated the chemical process behind a mysterious gastrointestinal disease that is becoming more frequent every day: the eosinophilic esophagitis (EoE), also known as the "asthma of the esophagus".

1 Sep 2015

Novel chemical virus can cross double lipid layer surrounding cells to release drugs

Viruses are able to redirect the functioning of cells in order to infect them. Inspired by their mode of action, scientists from the CNRS and Université de Strasbourg have designed a "chemical virus" that can cross the double lipid layer that surrounds cells, and then disintegrate in the intracellular medium in order to release active compounds.

29 Aug 2015

New non-invasive image processing technique may improve IVF success rates

A collaboration between biologists and engineers at Monash University has led to the development of a new non-invasive image processing technique to visualise embryo formation. Researchers were able to see, for the first time, the movement of all of the cells in living mammalian embryos as they develop under the microscope.

29 Aug 2015

Transplanting multi-layered sheet of liver cells into damaged liver improves function in test animals

Liver transplantation is currently the only established treatment for patients with end stage liver failure. However, this treatment is limited by the shortage of donors and the conditional integrity and suitability of the available organs. Transplanting donor hepatocytes (liver cells) into the liver as an alternative to liver transplantation also has drawbacks as the rate of survival of primary hepatocytes is limited and often severe complications can result from the transplantation procedure.

27 Aug 2015

ASTRO awards $675,000 to seven physician-researchers to advance radiation oncology research

The American Society for Radiation Oncology has selected seven leading physician-researchers to receive a total of $675,000 in awards and grants to advance radiation oncology research. Together, the seven funding grants, including ASTRO Junior Faculty Career Research Training Award, the ASTRO Residents/Fellows in Radiation Oncology Research Seed Award and the ASTRO/Radiation Oncology Institute Comparative Effectiveness Research Award, will support studies in radiation and cancer biology, radiation physics, translational research, outcomes/health services research and comparative effectiveness research within radiation oncology.

27 Aug 2015

Understanding the causes of sudden death in epilepsy: an interview with Professor Sanjay Sisodiya

SUDEP is the sudden unexpected witnessed or unwitnessed, non-traumatic and non-drowning death in people with epilepsy, with or without evidence of a seizure. It doesn’t necessarily have to be in the known context of a seizure, excluding documented status epilepticus, where people have seizure after seizure.

24 Aug 2015

Same-sex couples encounter more obstacles to infertility treatment compared to opposite-sex couples

Same-sex couples encounter more obstacles to treatment for infertility than opposite-sex couples, suggests a new study that will be presented at the 110th Annual Meeting of the American Sociological Association.

24 Aug 2015

AbVitro launches PairMe Grant Challenge to provide access to AbPair technology

AbVitro Inc., an immuno-oncology discovery company, today announced access to its AbPairTM technology by launching the "PairMe Grant Challenge."

20 Aug 2015

Blavatnik Biomedical Accelerator funds advanced biomedical research projects

A few years ago, Andrew Myers' laboratory discovered a new way to synthesize an important class of antibiotics that could one day tackle the toughest, most resistant infections.

20 Aug 2015

Mesenchymal stem cell exosomes offer hope in healing chronic wounds

Dr. Badiavas’ research demonstrates how mesenchymal stem cell (MSC) exosomes, cell-derived vesicles that exist in biological fluids, function to repair non-healing wounds.

19 Aug 2015

New OTEMTO phase three results show potential improvement to quality of life for COPD patients

Boehringer Ingelheim announced the publication of new data from the Phase IIIb OTEMTO® 1&2 trials (NCT01964352/NCT02006732), which show Spiolto® Respimat® (tiotropium/olodaterol) provides consistent, clinically meaningful improvements in quality of life versus placebo in patients with COPD

17 Aug 2015

Centenary Institute researchers take lead on promising new class of drugs for melanoma treatment

Researchers at Sydney’s Centenary Institute have taken the lead on a promising new class of drugs that may prove to be highly effective for the treatment of certain cases of melanoma.

14 Aug 2015

IVF may be less successful if donor eggs are frozen

Women who undergo in vitro fertilization (IVF) may be less likely to reach the stage of giving birth if the donor eggs used for the procedure are frozen rather than fresh, according to a new study published in the Journal of the American Medical Association.

13 Aug 2015

Scientists reveal how non-allergenic pollen mediators can increase allergic reactions

Scientists at Helmholtz Zentrum München and TU München discovered a new mechanism how non-allergenic pollen mediators can enhance allergic reactions. Especially the so-called B cells play a critical role in this process. The results were recently published in the Journal 'Allergy' and might lead to new approaches for therapies.