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Gene playing crucial role in immune system balance identified

A team led by St. Jude researchers identified a gene pivotal for immune system balance. Ultimately, the discovery may aid efforts to tame allergies and asthma.

12 Apr 2010

New methodology helps investigate unfolding of DNA

NYU Langone Medical Center researchers have developed a powerful new method to investigate the discrete steps necessary to turn on individual genes and examine how the process goes wrong in cancer and other diseases. The finding, based on seven years of research and described in the April 9 issue of Molecular Cell, allows scientists to investigate the unfolding of DNA, a process required for gene activation.

9 Apr 2010

Transcend Services submits $78.25M bid for acquisition of Spheris

TRANSCEND SERVICES, INC., the third largest provider of medical transcription services to the U.S. healthcare market, announced today that it has submitted a bid to acquire substantially all of the assets of Nashville, Tennessee-based Spheris, Inc. and the stock of its subsidiary for $78.25 million.

9 Apr 2010

Cancer research at Georgia Tech: Report

Cancer treatment typically involves surgery, radiation therapy, chemotherapy, hormone therapy or biological therapy. An oncologist may use one therapy or a combination of methods, depending on the type and location of the cancer, whether the disease has spread, the patient's age and general health, and other factors.

3 Apr 2010

MedQuist, AMI partner to provide CAC within CodeRunner coding workflow platform

MedQuist Inc., a leading provider of technology-enabled clinical documentation services, has announced an agreement with healthcare informatics software developer Artificial Medical Intelligence Inc. (AMI) to provide computer-assisted coding (CAC) within MedQuist's CodeRunner™ coding workflow platform.

2 Apr 2010

Brain stem cells in subventricular zone characterized by transcription factor Protein Tlx

The "cradle" of new neurons in the adult brain is well known. It is what is called the subventricular zone, a tissue structure lining the lateral ventricles. This is where neural or brain stem cells reside, which are responsible for generating new neurons if needed. For many years now, the subventricular zone has been suspected to be the origin of specific malignant brain tumors called gliomas, the most deadly type of which is glioblastoma.

2 Apr 2010

New approach may circumvent lost response in insulin due to obesity

Researchers at Children's Hospital Boston have identified a new strategy for treating type 2 diabetes, identifying a cellular pathway that fails when people become obese. By activating this pathway artificially, they were able to normalize blood glucose levels in severely obese and diabetic mice. Their findings will be published online by Nature Medicine on March 28.

29 Mar 2010

Ease of information capture and recordkeeping will help enable smoother transition to EHR systems

The proven ability of the medical transcription sector to deliver innovative, physician-friendly, and cost-effective solutions to the challenges of electronic health record (EHR) adoption will be the message taken to Capitol Hill by members of the Association for Healthcare Documentation Integrity (AHDI) and the Medical Transcription Industry Association (MTIA) for the organizations’ fifth-annual Advocacy Summit on March 24 in Washington, DC.

26 Mar 2010

Working of master regulator protein phosphatase 1

Protein phosphorylation is a process by which proteins are flipped from one activation state to another. It is a crucial function for most living beings, since phosphorylation controls nearly every cellular process, including metabolism, gene transcription, cell-cycle progression, cytoskeletal rearrangement and cell movement.

26 Mar 2010

New research may help advance treatment strategies for common liver disease

A research article published in the journal PloS Pathogens could lead to improvements in the production of vaccines for hepatitis A, the most widespread viral disease in the world.

26 Mar 2010

Protein deficiency in Down syndrome patients could contribute to cognitive impairment and congenital heart defects

Conventional wisdom among scientists for years has suggested that because individuals with Down syndrome have an extra chromosome, the disorder most likely results from the presence of too many genes or proteins contained in that additional structure.

24 Mar 2010

Cancer radiotherapy can increase risk of cardiovascular disease later in life

For an as yet unknown reason, cancer radiotherapy can increase the risk of cardiovascular disease later in life, a problem that is growing as more and more people survive their cancer diagnosis. New research from Karolinska Institutet now suggests that sustained inflammation induced by post-radiotherapy changes in the gene expression in the arteries could be the cause.

22 Mar 2010

Mayo Clinic co-led research finds first gene linked to lung cancer in "never smokers"

A five-center collaborative study that scanned the genomes of thousands of "never smokers" diagnosed with lung cancer as well as healthy never smokers has found a gene they say could be responsible for a significant number of those cancers.

22 Mar 2010

Survey unveils impact of gene regulation on human health

Researchers are only beginning to understand how individual variation in gene regulation can have a lasting impact on one's health and susceptibility to certain diseases. Now, an ambitious survey of the human genome has identified differences in the binding of master regulators called transcription factors to DNA that affect how genes are expressed in different people.

19 Mar 2010

Gene regulation rather than genes make us unique

Once the human genome was sequenced in 2001, the hunt was on for the genes that make each of us unique. But scientists at the European Molecular Biology Laboratory (EMBL) in Heidelberg, Germany, and Yale and Stanford Universities in the USA, have found that we differ from each other mainly because of differences not in our genes, but in how they're regulated - turned on or off, for instance.

18 Mar 2010

CDISC approves Nextrials as one of 15 registered solutions providers

Nextrials, Inc., a leader in clinical research software and services, has been approved by the Clinical Data Interchange Standards Consortium as one of 15 registered solutions providers, and is the only company offering an electronic data capture (EDC) product supporting the CDISC Healthcare Link Initiative.

17 Mar 2010

Human amniotic fluid skin cells "reprogrammed" to pluripotency

In a breakthrough that may help fill a critical need in stem cell research and patient care, researchers at Mount Sinai School of Medicine have demonstrated that skin cells found in human amniotic fluid can be efficiently "reprogrammed" to pluripotency, where they have characteristics similar to human embryonic stem cells that can develop into almost any type of cell in the human body. The study is online now and will appear in print in the next issue of the journal Cellular Reprogramming, to be published next month.

16 Mar 2010

Entrada receives venture funding to market health care platform nationwide

After the successful rollout of its clinical documentation and communication platform in the Southeast, Entrada has received venture funding to market the solution nationally to medical groups, hospitals, and electronic health record companies.

12 Mar 2010

MedQuist to provide DMC healthcare system with transcription outsourcing services

MedQuist Inc., a leading provider of technology-enabled clinical documentation services, today announced that it has been awarded a contract by Detroit Medical Center (DMC), a nationally respected healthcare system, to provide transcription outsourcing services. This award expands MedQuist's existing relationship to include services for Emergency Medicine documentation for six of DMC's major organizations: Children's Hospital, Detroit Receiving Hospital, Harper University Hospital, Huron Valley-Sinai Hospital, DMC Surgery, and Sinai-Grace Hospital.

11 Mar 2010