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Cytonet initiates clinical trial using liver cell infusion to treat urea cycle disorders in children

International biotechnology firm Cytonet recently launched the first ever clinical trial in the United States using an investigational liver cell infusion to treat urea cycle disorders (UCD) in children. The first patient in the Phase II trial, which will seek to enroll 20 patients in 12 medical centers, is a child with citrullinemia, which is a hereditary UCD. He received six liver cell infusions on six consecutive days at Yale School of Medicine in New Haven, Conn.

15 Apr 2011

Safer-sex education leads to fewer episodes of unprotected sex

Teaching young women how to prevent sexually transmitted infections (STIs) increases condom use and might reduce their number of sexual partners, but little research exists on whether educational programs reduce rates of STIs such as human papillomavirus, according to an updated research review from England.

15 Apr 2011

Astrocytes regulate circadian system that controls normal sleep patterns

The circadian system that controls normal sleep patterns is regulated by a group of glial brain cells called astrocytes, according to a study published online on April 14th in Current Biology, a Cell Press publication. Neuroscientists from Tufts University School of Medicine found that disruption of astrocyte function in fruit flies ( Drosophila) led to altered daily rhythms, an indication that these star-shaped glial cells contribute to the control of circadian behavior.

15 Apr 2011

Freedom Innovations announces license agreement for lower extremity prosthesis

Freedom Innovations, a company that specializes in the development of high technology lower extremity prosthetic devices, today announced a worldwide licensing agreement. The agreement grants the company exclusive rights to commercialize the world's first lower extremity prosthesis with actively powered knee and ankle joints that operate synergistically.

From PROTEOR 15 Apr 2011

Scientists identify novel small molecules that block human tumor cell growth

Researchers from the Cancer Institute at NYU Langone Medical Center have identified three novel small molecules that interrupt a crucial cellular communication pathway that regulates many aspects of development and cancer.

15 Apr 2011

Insight into Cervical Spondylotic Myelopathy

Researchers at the Krembil Neuroscience Centre, Toronto Western Hospital have identified a cell receptor, which is responsible for cell death in the spinal cord in a condition called Cervical Spondylotic Myelopathy.

15 Apr 2011

Chamberlain introduces new N2N Scholarship Program for nurses

The cost of a college education and the stress of making the transition from high school to college are two common areas of concern among high school students as they near graduation. Chamberlain College of Nursing is looking to ease these concerns through its new Navigate to Nursing Scholarship Program.

15 Apr 2011

Researchers classify chronic ulcerative stomatitis as a new autoimmune disease

In the first study investigating the origins of a little-known condition called chronic ulcerative stomatitis, researchers at Tufts University School of Dental Medicine provide evidence that an autoimmune response contributes to the painful oral sores that characterize the disease. The study findings support the classification of CUS as a new autoimmune disease.

15 Apr 2011

Researchers temporarily turn off essential gene using RNAi technology

One way of discovering a gene's function is to switch it off and observe how the loss of its activity affects an organism. If a gene is essential for survival, however, then switching it off permanently will kill the organism before the gene's function can be determined. Researchers at Cold Spring Harbor Laboratory (CSHL) have overcome this problem by using RNA interference (RNAi) technology to temporarily turn off any essential gene in adult mice and then turn it back on before the change kills the animals.

15 Apr 2011

Walking slows progression of nonalcoholic fatty liver disease in obese people

Walking on a treadmill for one hour a day may slow the progression of nonalcoholic fatty liver disease in obese people with prediabetes by jump-starting their metabolism and slowing the oxidative damage wrought by the condition, say researchers at the Cleveland Clinic.

15 Apr 2011

Study identifies why salt-sensitive hypertension develops

New research from Case Western Reserve University School of Medicine and Kent State University shows that salt intake raises blood pressure because it makes it harder for the cardiovascular system to simultaneously juggle the regulation of blood pressure and body temperature.

15 Apr 2011

Diet and exercise most effective when done together for losing weight and body fat

Everyone knows that eating a low-fat, low-calorie diet and getting regular exercise helps shed pounds, but a new study led by researchers at Fred Hutchinson Cancer Research Center has found that when it comes to losing weight and body fat, diet and exercise are most effective when done together as compared to either strategy alone.

15 Apr 2011

Researchers develop sensor film to estimate packaged food quality

When it comes to packaged fish or meat, it is nearly impossible to distinguish between fresh goods and their inedible counterparts. Researchers have now developed a sensor film that can be integrated into the package itself, where it takes over the role of quality control. And if the food has spoiled, it changes color to announce the fact.

15 Apr 2011

Women consume more non-prescribed drugs than men

Approximately 20% of Spaniards take non-prescribed medication and women are the group most inclined towards this practice. This is the conclusion of a research study carried out by experts from the Rey Juan Carlos University in Madrid, which also links this habit to nationality, income level and alcohol and tobacco consumption amongst the population.

15 Apr 2011

ACE survey: 55% of patient with type 2 diabetes experience hypoglycemia

New survey data released today at the American Association of Clinical Endocrinologists 20th Annual Meeting and Clinical Congress reveal that more than half of people with type 2 diabetes across the country report they have experienced hypoglycemia, or low blood sugar.

15 Apr 2011

Study finds association between C-reactive protein and memory decline

High levels of a protein associated with chronic, low-grade inflammation in the brain correlate with aspects of memory decline in otherwise cognitively normal older adults, according to a study led by scientists at the University of California, San Francisco.

15 Apr 2011

Botox may offer new hope for patients with low cerebrospinal fluid headaches

A Mayo Clinic case study finds Botox may offer new hope to patients suffering disabling low cerebrospinal fluid headaches. The successful treatment also offers new insight into Botox and headache treatment generally.

15 Apr 2011

CMS, AAPC partner to conduct 'Code-A-Thon' webinar for health care providers

AAPC is collaborating with the Centers for Medicare & Medicaid Services to plan and conduct an AAPC-sponsored ICD-10 "Code-A-Thon" webinar on Tuesday, April 26, 2011.

12 Apr 2011

Study finds 27% increase in pediatric and adolescent football-related injuries in the U.S.

A new study conducted by researchers in the Center for Injury Research and Policy of The Research Institute at Nationwide Children's Hospital found that an estimated 5.25 million football-related injuries among children and adolescents between 6 and 17 years of age were treated in U.S. emergency departments between 1990 and 2007.

12 Apr 2011

Breast cancer patients can benefit from new nanobodies

A new discovery published online in The FASEB Journal promises to help physicians identify patients most likely to benefit from breast cancer drug therapies. If the compound, called "Nanobody," proves effective in clinical trials, it would represent a significant advance for breast cancer drug therapy because some drugs are effective only in some people.

12 Apr 2011