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MDC researchers provide new insights on embryonic heart development

When it first starts to develop, the heart is a simple tube. Reporting in the journal Nature Communications, researchers at MDC have now described how it forms itself into a its characteristic S-shape and how the ventricles and atria finally develop.

4 Jun 2018

Study finds important factors to improve transfer of patients from ICU to general hospital ward

A new study has identified important factors that can improve the transfer of patients from the intensive care unit to a general hospital ward, a high-risk transition in which breakdowns in communication, medical errors and adverse events resulting in readmission can occur.

4 Jun 2018

Researchers discover new medicine that may fight against monogenic obesity

Around two to six per cent of all people with obesity develop obesity already in early childhood; it's in their genetic cards.

4 Jun 2018

Researchers use 'multiomics' approach to study newborn mouse heart

During the first days of life, the heart of a newborn mouse adapts to entirely new physiological conditions, larger volume loads and an increased energy demand. As a result, fundamental changes occur in the heart. Studies have shown that the heart of neonate mouse retains its ability to effectively repair tissue damage.

4 Jun 2018

Study sheds light on how medical providers use SO/GI data to treat patients

Collecting sexual orientation and gender identity, or "SO/GI," data has valuable public health benefits and potential clinical benefits for an individual patient, but medical providers must continue to collect information about patient experiences and behaviors, where clinically appropriate, and avoid making assumptions based on SO/GI data alone, according to a study from researchers at the Perelman School of Medicine at the University of Pennsylvania published today in the Journal of General Internal Medicine.

4 Jun 2018

Genomic markers can predict lynch syndrome across tumor types

Microsatellite instability and DNA mismatch repair deficiencies can predict Lynch syndrome across tumor types, according to researchers from Memorial Sloan Kettering Cancer Center, who presented this retrospective data analysis in a press conference at the annual meeting of the American Society of Clinical Oncology.

4 Jun 2018

Bubble pop? Brownie batter? Vapes’ added flavors fuel e-cig debate

A heated debate is redrawing alliances in the tobacco control movement as federal officials wrestle with how to regulate the growing e-cigarette market.

4 Jun 2018

Detailed structure of protein pair offers blueprint for new medicines

Walter and Eliza Hall Institute researchers have visualized for the first time how the protein SOCS1 'switches off' cell signaling to dampen immune responses and block cancer growth.

4 Jun 2018

Protein inhibitor drug found to be safe and effective in treating patients with acute myeloid leukemia

Ivosidenib, an experimental drug that inhibits a protein often mutated in several cancers has been shown to be safe, resulting in durable remissions, in a study of acute myeloid leukemia with relapsed or refractory disease.

4 Jun 2018

MicroRNAs may hold key to predict how someone is affected by sleep loss

The key to predicting how someone is affected by sleep loss may be found in microRNAs, according to a new study from researchers at the Perelman School of Medicine at the University of Pennsylvania.

4 Jun 2018

Diuretic drug may be just as effective as oral antibiotics to treat acne in female patients

In a finding that suggests the potential for practice change that would reduce the use of antibiotics in dermatology, researchers in the Perelman School of Medicine at the University of Pennsylvania have found the diuretic drug spironolactone may be just as effective as antibiotics for the treatment of women's acne.

4 Jun 2018

Poor sleep linked to junk food cravings, nighttime snacking, obesity, and diabetes

Nighttime snacking and junk food cravings may contribute to unhealthy eating behaviors and represent a potential link between poor sleep and obesity, according to a study by University of Arizona Health Sciences sleep researchers.

1 Jun 2018

Phase I trial shows safety of investigational drug in treating chronic lymphocytic leukemia

Reporting results from a first-in-human phase I clinical trial, researchers at University of California San Diego School of Medicine have found that treatment with cirmtuzumab, an experimental monoclonal antibody-based drug, measurably inhibited the "stemness" of chronic leukemia cancer cells - their ability to self-renew and resist terminal differentiation and senescence.

1 Jun 2018

New autism screening app appears to be caregiver-friendly and reliable

A study of an iPhone app used to screen young children for signs of autism shows that the app is a novel, easy to use, and scalable method for collecting high-quality and scientifically valid data, according to a new study published June 1 in the journal npj Digital Medicine.

1 Jun 2018

New guidelines address all components of nutrition for critically ill patients

A new nutrition bundle strives to ensure that critically ill patients receive adequate nutrition while hospitalized and seeks to reduce adverse outcomes related to malnutrition.

1 Jun 2018

Researchers seek to characterize financial health of surgical residents

The cost of education is continuing to increase, and the amount of debt for medical school graduates has risen dramatically in the last two decades, according to the Association of American Medical Colleges.

1 Jun 2018

Opdivo plus low-dose Yervoy shows promising results in treating renal cell carcinoma patients

Bristol-Myers Squibb Company today announced patient-reported outcomes data from the Phase 3 CheckMate -214 trial in intermediate- and poor-risk patients with advanced renal cell carcinoma treated with the Immuno-Oncology combination Opdivo plus low-dose Yervoy versus sunitinib over a two-year follow-up period.

1 Jun 2018

MD Anderson and Amgen collaborate to accelerate early-stage oncology therapies

The University of Texas MD Anderson Cancer Center and Amgen today announced two multi-year collaboration agreements aimed at accelerating development of a variety of Amgen's early-stage oncology therapies for patients with leukemia, myelodysplastic syndromes, multiple myeloma, small-cell lung cancer, and other non-lung cancers with small-cell histologies.

1 Jun 2018

Researchers develop mineralized materials that could regenerate hard tissues

Researchers at Queen Mary University of London have developed a new way to grow mineralized materials which could regenerate hard tissues such as dental enamel and bone.

1 Jun 2018

Screening preemies for microRNA biomarkers may allow early intervention of cerebral palsy

As the first step toward predicting cerebral palsy in premature infants, scientists have identified a panel of microRNAs that are changed in babies who later develop abnormal muscle tone.

1 Jun 2018