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Clinical trial examining the combination of atezolizumab and chemoradiation for patients with limited-stage SCLC reaches accrual

The NRG Oncology/Alliance clinical trial NRG-LU005, examining the addition of the immunotherapy drug atezolizumab combined with chemoradiation for patients with limited-stage small cell lung cancer (SCLC) recently reached the trial's accrual goal of 506 patients.

8 Jul 2022

Study illustrates how the use of whole exome sequencing can better predict treatment response

Immunotherapies, such as immune checkpoint inhibitors, have transformed the treatment of advanced stage cancers.

8 Jul 2022

Moffitt researchers discover kidney cancer-specific splicing variant biomarkers

Kidney cancer accounts for only 4% of all cancers in the United States; however, its incidence has more than doubled since 1975, with the most common type being clear cell renal cell carcinoma.

8 Jul 2022

Moffitt researchers discover how YAP1 protein contributes to angiogenesis in cancers

The formation of new blood vessels, also known as angiogenesis, is critical to the development and progression of cancer.

8 Jul 2022

Brief online art viewing can have positive effects on well-being

Viewing art while visiting galleries and museums can have powerful effects on an individual's mood, stress and well-being. But does the same hold true for viewing art in digital space? A new study by psychologists led by MacKenzie Trupp, and Matthew Pelowski investigated whether engaging with art online also has this effect.

8 Jul 2022

Study offers a new understanding of the evolutionary diversification of KNL2 gene

In living organisms cells divide and reproduce in two ways, mitosis and meiosis. Mitosis results in two identical daughter cells, whereas meiosis results in four sex cells.

8 Jul 2022

Study finds microglia to be responsible for neuronal death in a mitochondrial disease animal model

Microglia, a type of central nervous system cell, is primarily responsible for neuronal death in Leigh Syndrome and the neurological symptoms related to this mitochondrial disease.

8 Jul 2022

Commercial antibodies do not recognize immune receptor ACKR1

Antibodies are among the most frequently used tools in the biosciences, as they enable researchers to identify molecules.

8 Jul 2022

Genetically-enhanced biocontrols can help eradicate invasive alien mammals

Invasive alien mammals can have catastrophic impacts on native flora and fauna, causing species extinctions and driving profound environmental change.

8 Jul 2022

Researchers unravel the functioning of antibodies in autoimmune encephalitis

Using a state-of-the-art method, researchers at DZNE and the University of Texas have succeeded for the first time at unraveling the effects of autoimmune antibodies, that are directed against the brain, in detail at the atomic level.

8 Jul 2022

Study shows how tau protein, critical to Alzheimer's, turns from normal to diseased state

Alzheimer’s disease, the most common form of dementia, currently has no cure or effective therapy, in part due to gaps in our understanding of how the progressive neurodegenerative disorder arises in the brain.

8 Jul 2022

GI cancer survival rates improving among Northern Territorians except for Aboriginal and Torres Strait Islander people

Survival rates for gastrointestinal (GI) cancer among Northern Territorians have improved in the past 30 years but Aboriginal and Torres Strait Islander peoples living in the Territory still have worse survival outcomes, a new analysis has found.

8 Jul 2022

Study aims to determine the advantages of using robots in hip replacement surgery

Robots will have their surgical skills put to the test as researchers trial their use in hip replacement surgery for the first time.

8 Jul 2022

New non-invasive treatment for patients suffering from treatment-resistant depression and dementia

A joint research team from the LKS Faculty of Medicine, The University of Hong Kong (HKUMed) and City University of Hong Kong (CityU) has discovered that the electrical stimulation of the eye surface can alleviate depression-like symptoms and improve cognitive function in animal models.

8 Jul 2022

Disrupting genes in the yeast Pichia pastori to increase its secretory production of useful proteins

A collaboration including researchers from Kobe University, University of Tokyo and Tohoku University has successfully identified and disrupted genes in the yeast Pichia pastoris (1) in order to increase its secretory production of useful proteins (2).

8 Jul 2022

Characterization of longer-term effects on behavior and brain inflammation following recovery from mild COVID-19

A recent study reported that long COVID in mice causes brain inflammation and cognitive impairment.

8 Jul 2022

Vaccine and testing delays for monkeypox echo failures in early covid response

Andy Stone is one of the lucky ones. The New York City resident saw a tweet from a local AIDS activist saying that monkeypox vaccines would be available that day at a clinic in Manhattan

8 Jul 2022

The search for scarce formula is worse for rural families on WIC

Two months after giving birth, Jennifer Magee noticed a change in her baby's feeding routine that scared her: She was starting to drink more formula, almost every hour.

8 Jul 2022

The push for abortion lawmaking after ‘Dobbs’ is unique, legal and political experts say

The end of nationwide abortion protections has been met with a wave of calls from lawmakers and governors in at least a dozen states for special legislative sessions that would reshape the state-by-state patchwork of laws that now govern abortion in the U.S.

8 Jul 2022

Digital mental health companies draw scrutiny and growing concerns

When Pat Paulson's son told her he was feeling anxious and depressed at college, Paulson went through her Blue Cross Blue Shield provider directory and started calling mental health therapists.

8 Jul 2022

Research News and Research

Clinical trial examining the combination of atezolizumab and chemoradiation for patients with limited-stage SCLC reaches accrual

Study illustrates how the use of whole exome sequencing can better predict treatment response

Moffitt researchers discover kidney cancer-specific splicing variant biomarkers

Moffitt researchers discover how YAP1 protein contributes to angiogenesis in cancers

Brief online art viewing can have positive effects on well-being

Study offers a new understanding of the evolutionary diversification of KNL2 gene

Study finds microglia to be responsible for neuronal death in a mitochondrial disease animal model

Commercial antibodies do not recognize immune receptor ACKR1

Genetically-enhanced biocontrols can help eradicate invasive alien mammals

Researchers unravel the functioning of antibodies in autoimmune encephalitis

Study shows how tau protein, critical to Alzheimer's, turns from normal to diseased state

GI cancer survival rates improving among Northern Territorians except for Aboriginal and Torres Strait Islander people

Study aims to determine the advantages of using robots in hip replacement surgery

New non-invasive treatment for patients suffering from treatment-resistant depression and dementia

Disrupting genes in the yeast Pichia pastori to increase its secretory production of useful proteins

Characterization of longer-term effects on behavior and brain inflammation following recovery from mild COVID-19

Vaccine and testing delays for monkeypox echo failures in early covid response

The search for scarce formula is worse for rural families on WIC

The push for abortion lawmaking after ‘Dobbs’ is unique, legal and political experts say

Digital mental health companies draw scrutiny and growing concerns

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