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Polygenic risk score predicts early-onset heart disease risk

A risk score based on multiple genetic differences, or polygenic risk score, predicted significantly more cases of early-onset heart disease than standard tests for single genetic defects, according to new research in the American Heart Association's journal Circulation: Genomic and Precision Medicine.

8 Jan 2018

Obese adolescents show improvements in cardiovascular disease risk factors after bariatric surgery

Adolescents with severe obesity who had bariatric surgery showed significant improvements in cardiovascular disease risk factors, according to the most recent "Teen Longitudinal Assessment of Bariatric Surgery" (Teen-LABS) study, published online today by Pediatrics.

8 Jan 2018

New program improves outcomes for older people undergoing elective surgery

Compared to younger adults, older people have higher rates of complications from surgery. But many problems can be avoided by intervening with assessments and risk-reduction strategies before, during and after procedures.

5 Jan 2018

Bielefeld scientists discover cause of initially unclear symptoms

The sequencing of the human genome has made it possible: nowadays scientists can discover potential disorders for which there are no known patients.

5 Jan 2018

Targeted fluorescence successfully identifies pulmonary metastases in osteosarcoma patient

In a proof-of-principle case report, researchers announce that targeted fluorescence successfully identified pulmonary metastases in a patient with osteosarcoma, making it easier for surgeons to locate the tumors for resection.

5 Jan 2018

Researchers pinpoint mechanism for conversion of white fat into brown fat

An international team of researchers led from Karolinska Institutet have, in experiments on mice, pinpointed a mechanism for the conversion of energy-storing white fat into energy-expending brown fat.

5 Jan 2018

Smoke shops may be potential ‘nuisance properties’ in urban communities of color

Tobacco shops, also known as smoke shops, may represent potential "nuisance properties" in urban communities of color, a study led by a researcher at the University of California, Riverside has found.

5 Jan 2018

Astronauts' body temperature increases when exposed to weightlessness

Astronauts float weightlessly through space, and the condition of weightlessness is something many would love to experience.

5 Jan 2018

Strategies to prevent and treat acute chest syndrome in children with sickle cell disease

Acute chest syndrome (ACS), a potentially severe lung complication of sickle cell disease, increases a child's risk of respiratory failure, chronic lung disease, and prolonged hospitalization if not recognized early and treated effectively.

5 Jan 2018

Study identifies how excess fat disrupts heart cells' ability to produce energy

A University of Iowa study has identified how excess fat in the heart, a common feature in diabetes and obesity, can harm the cells' essential ability to produce energy.

5 Jan 2018

Safety tips to prevent carbon monoxide poisoning during winter

On January 4, 2018, a 13-year-old girl died and dozens of people were injured by carbon monoxide poisoning in Perth Amboy, NJ.

5 Jan 2018

HSS researchers win grant to determine if stem cell therapy can improve outcomes for rotator cuff tears

A multidisciplinary team led by Scott Rodeo, MD, and Christopher Mendias, PhD, at Hospital for Special Surgery has been awarded the Orthopaedic Research and Education Foundation Clinical Research Grant in Cellular Therapy in honor of James Urbaniak, MD in Collaboration with National Stem Cell Foundation.

5 Jan 2018

Stem cell transplant improves survival among scleroderma patients

Scleroderma with internal organ involvement is a debilitating and lethal autoimmune disorder with few effective treatments. But a study led by Duke Health researchers has found new cause for optimism using an aggressive stem cell transplant regimen.

5 Jan 2018

Experimental device could help ease tinnitus symptoms by targeting unruly nerve activity in the brain

Millions of Americans hear ringing in their ears -- a condition called tinnitus -- but a new study shows an experimental device could help quiet the phantom sounds by targeting unruly nerve activity in the brain.

5 Jan 2018

Newly described super-silenced DNA reveals novel approach to reprogram cells

Newly described stretches of super-silenced DNA reveal a fresh approach to reprogram cell identity to use in regenerative medicine studies and one day in the clinic, according to a study in Molecular Cell last week by investigators from the Perelman School of Medicine at the University of Pennsylvania.

5 Jan 2018

Genetic differences can influence efficiency of medicines

Medicines do not follow the one size fits all principle, because genetic differences can influence their efficiency.

5 Jan 2018

Researchers use genomic technologies to better understand risk factor for stomach cancer

A research team led by National University Health System and Duke-NUS Medical School has used genomic technologies to better understand intestinal metaplasia, a known risk factor for gastric (stomach) cancer.

5 Jan 2018

New type of skin patch may provide possible answer to antibiotic resistance crisis

A team of researchers from Queen's University Belfast, led by Professor Ryan Donnelly, Professor of Pharmaceutical Technology are developing a new type of skin patch (microarray patch) that administers drugs directly into the bloodstream through thousands of individual "microneedles" which are being tested as a possible answer to the antibiotic resistance crisis.

5 Jan 2018

Study suggests vitamin C enhances tuberculosis drugs effectiveness

A new study conducted by researchers at the Albert Einstein College of Medicine, Bronx, NY, proposed the use of vitamin C together with tuberculosis drugs for rapid eradication of the disease-causing pathogens. The studies were carried out on mice and in tissue cultures and the results have been published in the journal of American Society for Microbiology, Antimicrobial Agents and Chemotherapy.

5 Jan 2018

Specific bacteria in the intestines can improve response rate to cancer immunotherapy

In the Jan. 5, 2018 issue of Science, researchers from the University of Chicago Medicine show that specific strains of commensal bacteria – the swarms of microorganisms naturally dwelling in the intestines – can improve the response rate to immunotherapy for patients being treated for advanced melanoma.

5 Jan 2018

Medicine News and Research

Polygenic risk score predicts early-onset heart disease risk

Obese adolescents show improvements in cardiovascular disease risk factors after bariatric surgery

New program improves outcomes for older people undergoing elective surgery

Bielefeld scientists discover cause of initially unclear symptoms

Targeted fluorescence successfully identifies pulmonary metastases in osteosarcoma patient

Researchers pinpoint mechanism for conversion of white fat into brown fat

Smoke shops may be potential ‘nuisance properties’ in urban communities of color

Astronauts' body temperature increases when exposed to weightlessness

Strategies to prevent and treat acute chest syndrome in children with sickle cell disease

Study identifies how excess fat disrupts heart cells' ability to produce energy

Safety tips to prevent carbon monoxide poisoning during winter

HSS researchers win grant to determine if stem cell therapy can improve outcomes for rotator cuff tears

Stem cell transplant improves survival among scleroderma patients

Experimental device could help ease tinnitus symptoms by targeting unruly nerve activity in the brain

Newly described super-silenced DNA reveals novel approach to reprogram cells

Genetic differences can influence efficiency of medicines

Researchers use genomic technologies to better understand risk factor for stomach cancer

New type of skin patch may provide possible answer to antibiotic resistance crisis

Study suggests vitamin C enhances tuberculosis drugs effectiveness

Specific bacteria in the intestines can improve response rate to cancer immunotherapy

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Improving healthcare sustainability through carbon data

Managing vibration in IVF laboratories

A New Approach to Preventing Bladder Cancer Recurrence

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