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Positive results from Affinium Pharmaceuticals' Phase 2a clinical trial of AFN-1252 in ABSSSI

Affinium Pharmaceuticals announced today that its Phase 2a clinical trial evaluating oral AFN-1252 in acute bacterial skin & skin structure infections demonstrated excellent efficacy and safety data, marking a significant proof-of-concept milestone for Affinium's first-in-class, novel antibiotic targeted against bacterial fatty acid biosynthesis inhibition (FabI inhibitors).

21 Mar 2013

Phase II trial results of OHR/AVR118 in patients with cancer cachexia announced

Ohr Pharmaceutical, a pharmaceutical company focused on the development of novel therapeutics for large unmet medical needs, today announced the results of a Phase II trial to evaluate the effects of OHR/AVR118 in advanced cancer patients with cachexia. Cancer cachexia is the complex, multi-symptom syndrome seen in late-stage cancer patients, characterized by anorexia and unintended loss of appetite, progressive and continual weight loss, accompanied by generalized host tissue wasting, skeletal muscle atrophy, immune and metabolic dysfunction, and a greatly diminished quality of life.

21 Mar 2013

WUSTL's Wang receives NSF grant to study oxygen consumption rates of individual cells

When scientists study cells, they need to know how much oxygen each cell consumes to determine its metabolism. However, existing technology limits this study to groups of cells, not individual cells. Lihong Wang, PhD, plans to change that.

21 Mar 2013

Investigators examine effectiveness of probiotics for cancer treatment

One may not think of probiotics -- like those found in yogurt that promote good digestive health -- as a weapon used in the fight against cancer. But that is the focus of investigators at The Cancer Institute of New Jersey, who are examining the effectiveness of probiotics as they relate to the outcomes of bone marrow transplant for patients with blood cancers.

21 Mar 2013

GlobalPost, humanitarian agencies examine impact of childhood TB

Noting the WHO and the Global Fund to Fight AIDS, Tuberculosis and Malaria on Monday issued a joint statement calling for an additional $1.6 million a year to fight tuberculosis (TB) in low- and middle-income countries, GlobalPost's "Global Pulse" blog examines the global impact of childhood TB, writing, "While health officials did not single out the devastating impact of the disease on children ... WHO estimates that at least 500,000 children contract TB each year and that 70,000 die from the disease, largely in Asia and Africa."

21 Mar 2013

New research may help clinicians determine factors that increase risk of blood clots after surgery

New research from the UC Davis Comprehensive Cancer Center, published in the Journal of Surgical Research, may help clinicians determine which patients are at highest risk for post-surgical blood clots in the legs or lungs.

21 Mar 2013

AANS, CNS urge Congress to restore Medicare payments for stereotactic radiosurgery

he American Association of Neurological Surgeons and Congress of Neurological Surgeons are urging Congress to restore Medicare hospital outpatient payment rates for Cobalt-60-based stereotactic radiosurgery to those in place prior to the enactment of the American Taxpayer Relief Act.

21 Mar 2013

Patient-centered end-of-life care results in happier patients who live longer, researchers find

New doctors take an oath to first do no harm, but physicians often go too far in their quest to keep that oath - exposing patients to aggressive treatments that don't improve outcomes and drive up healthcare costs.

21 Mar 2013

Study examines overuse of ER for nonemergency visits

Visits to the ER are not always for true medical emergencies - and some policymakers have been fighting the problem by denying or limiting payments if the patient's diagnosis upon discharge is for "nonemergency" conditions.

21 Mar 2013

CPF and PFF to partner with ATS to fund pulmonary fibrosis research

The Coalition for Pulmonary Fibrosis, the Pulmonary Fibrosis Foundation, and the American Thoracic Society-the world's leading professional organization for pulmonary, critical care and sleep medicine-today announced that the CPF and the PFF will again partner with the ATS to fund pulmonary fibrosis research.

21 Mar 2013

Independent maternal demographic factors can predict likelihood of operative births in UK: Study

Independent maternal demographic factors such as social status, ethnicity and maternal age can predict the likelihood of operative births in the UK, according to a new study published today (20 March) in BJOG: An International Journal of Obstetrics and Gynaecology.

21 Mar 2013

New imaging agent detects, maps cancers that have reached lymph nodes

Researchers at the University of California, San Diego School of Medicine have shown that a new imaging dye, designed and developed at UC San Diego Moores Cancer Center, is an effective agent in detecting and mapping cancers that have reached the lymph nodes.

21 Mar 2013

Viewpoints: N.D. abortion law is 'repressive and extreme;' States identify 'promising' ideas to overhaul medical malpractice

Late last week, the North Dakota legislature passed a bill that would ban a woman from having an abortion as soon as the heartbeat of the fetus is detected, which can happen as early as six weeks into a pregnancy.

21 Mar 2013

Study: Drug normally used to treat severe bronchial asthma beneficial for chronic urticaria sufferers

An international study involving dermatologists from the Hospital del Mar and Spanish subjects has concluded that a drug normally used to treat severe bronchial asthma caused by allergies (Omalizumab) rapidly eliminates the symptoms of spontaneous chronic urticaria, a development that it is expected will significantly improve the quality of life of chronic urticaria sufferers.

21 Mar 2013

Survivors of childhood leukemia and lymphoma are at greater risk of chronic fatigue: Study

Chronic fatigue, a persistent lack of energy that does not improve with rest, is at least three times more prevalent among adult survivors of acute lymphoblastic leukemia and lymphoma experienced during childhood or adolescence than in the general adult population, according to an article in Journal of Adolescent and Young Adult Oncology, a multidisciplinary peer-reviewed publication from Mary Ann Liebert, Inc., publishers.

21 Mar 2013

Combination of HUCBCs and Simvastatin offers promising therapy for stroke: Study

Researchers at the Henry Ford Health System (Detroit, MI) and colleagues at Saneron CCEL Therapeutics, Inc. of Tampa, Florida, have found that when human umbilical cord blood cells were transplanted into test rats modeled with stroke, the addition of Simvastatin to the HUCBCs significantly increased the therapeutic benefit of the HUCBCs.

21 Mar 2013

Lobbyists update strategy to repeal health law medical device tax

The New York Times reports on that industry lobbyists are courting Democrats. Meanwhile, in other congressional news, two House lawmakers have reintroduced legislation to improve Medicare's Recovery Audit Program.

21 Mar 2013

Database offers national overview of hospital violation reports

Stateline reports that information about hospital errors dating back to January 2011 will be available to the public on a new website. Meanwhile, a report by the Robert Wood Johnson draws parallels between the nation's most unhealth counties and those that have the highest rates of preventable hospital stays.

21 Mar 2013

New biodegradable nanoparticles deliver inflammation-resolving drugs to sites of tissue injury

A multicenter team of researchers, including scientists at Columbia University Medical Center (CUMC), Brigham and Women's Hospital (BWH), Mount Sinai School of Medicine, and Massachusetts Institute of Technology, has developed biodegradable nanoparticles that are capable of delivering inflammation-resolving drugs to sites of tissue injury.

20 Mar 2013

Multipotent stem cells in deer antler may have regenerative uses in veterinary medicine

A team of researchers in Seoul, Korea have reported finding evidence that deer antlers - unique in that they regenerate annually - contain multipotent stem cells that could be useful for tissue regeneration in veterinary medicine.

20 Mar 2013

Hospital News and Research

Positive results from Affinium Pharmaceuticals' Phase 2a clinical trial of AFN-1252 in ABSSSI

Phase II trial results of OHR/AVR118 in patients with cancer cachexia announced

WUSTL's Wang receives NSF grant to study oxygen consumption rates of individual cells

Investigators examine effectiveness of probiotics for cancer treatment

GlobalPost, humanitarian agencies examine impact of childhood TB

New research may help clinicians determine factors that increase risk of blood clots after surgery

AANS, CNS urge Congress to restore Medicare payments for stereotactic radiosurgery

Patient-centered end-of-life care results in happier patients who live longer, researchers find

Study examines overuse of ER for nonemergency visits

CPF and PFF to partner with ATS to fund pulmonary fibrosis research

Independent maternal demographic factors can predict likelihood of operative births in UK: Study

New imaging agent detects, maps cancers that have reached lymph nodes

Viewpoints: N.D. abortion law is 'repressive and extreme;' States identify 'promising' ideas to overhaul medical malpractice

Study: Drug normally used to treat severe bronchial asthma beneficial for chronic urticaria sufferers

Survivors of childhood leukemia and lymphoma are at greater risk of chronic fatigue: Study

Combination of HUCBCs and Simvastatin offers promising therapy for stroke: Study

Lobbyists update strategy to repeal health law medical device tax

Database offers national overview of hospital violation reports

New biodegradable nanoparticles deliver inflammation-resolving drugs to sites of tissue injury

Multipotent stem cells in deer antler may have regenerative uses in veterinary medicine

Event guide: 4th Extra-Hepatic Lipid-Based Nanoparticles Delivery Summit eBook

Improving healthcare sustainability through carbon data

Managing vibration in IVF laboratories

A New Approach to Preventing Bladder Cancer Recurrence

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