Immune Response News and Research

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Study finds surprising defensive functions of the immune system against new viral attacks

Scientists are opening new windows into understanding more about the constantly shifting evolutionary arms race between viruses and the hosts they seek to infect.

29 Jan 2021

New gene-based vaccine strategy receives grant from the Bill & Melinda Gates Foundation

The AAVCOVID vaccine program, a novel gene-based vaccine strategy that utilizes an adeno-associated virus (AAV) vector, was granted an award for up to $2.1 million from the Bill & Melinda Gates Foundation.

29 Jan 2021

Researchers develop ‘next-generation vaccine platform’ against SARS-CoV-2

Researchers have designed a subunit vaccine based on the SARS-CoV-2 spike protein co-administered with CpG (Oligodeoxyribonucleotides) adjuvant.

29 Jan 2021

Study: Targeting glycoprotein could improve response to cancer immunotherapy

It was an unexpected discovery that started with an analysis of more than 1,000 genes. The question: why game-changing cancer immunotherapy treatments work for only a fraction of patients.

28 Jan 2021

New machine learning model predicts COVID-19 severity

COVID-19 vaccine distribution has begun across the globe, while many countries are still struggling with the rampant rise of infections.

28 Jan 2021

Neurological and psychiatric complications six months after COVID-19 recovery

Researchers in the United Kingdom have aimed to determine the prevalence of patients who experience neurological and psychiatric conditions six months after recovering from COVID-19.

28 Jan 2021

Substances in tick saliva activate immune response-suppressing proteins in cattle

A tick saliva study reveals immune responses that could lead to better protection for cattle.

28 Jan 2021

Genetic changes in tumors can help predict the efficacy of immunotherapy drugs

Researchers at the Francis Crick Institute, the UCL Cancer Institute, and the Cancer Research UK Lung Cancer Centre of Excellence have identified genetic changes in tumors which could be used to predict if immunotherapy drugs would be effective in individual patients.

28 Jan 2021

Melatonin synthesized in the lungs acts as a barrier against SARS-CoV-2

Melatonin synthesized in the lungs acts as a barrier against SARS-CoV-2, preventing expression of genes that encode proteins in cells such as resident macrophages in the nose and pulmonary alveoli, and epithelial cells lining the alveoli, all of which are entry points for the virus.

28 Jan 2021

Ebola survivors experienced a resurgence in antibody levels after recovery

A high proportion of survivors of Ebola experienced a resurgence in antibody levels nearly a year after recovery, a new University of Liverpool study has found.

27 Jan 2021

Study provides a detailed look at vulnerable sites on SARS-CoV-2

A new study led by scientists at La Jolla Institute for Immunology (LJI) suggests that T cells try to fight SARS-CoV-2 by targeting a broad range of sites on the virus--beyond the key sites on the virus's spike protein.

27 Jan 2021

Researchers figure out how the immune system keeps tabs on the brain

Alzheimer's disease, multiple sclerosis, autism, schizophrenia and many other neurological and psychiatric conditions have been linked to inflammation in the brain.

27 Jan 2021

Temperature, latitude correlate with COVID-19 cases and mortality rates

With cities around the globe locking down yet again amid soaring COVID-19 numbers, could seasonality be partially to blame? New research from the University of Illinois says yes.

27 Jan 2021

Biliverdin shields SARS-CoV-2 from host antibody response, study finds

A team of international scientists has recently revealed that severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) interacts with two heme metabolites, bilirubin and biliverdin, to escape the antibody-mediated host immune responses.

27 Jan 2021

What do we know about the SARS-CoV-2 vaccines so far?

A new study surveys what we know so far about SARS-CoV-2 vaccine candidates from advanced clinical trials.

27 Jan 2021

Purdue University-affiliated startup receives NSF grant to study severe COVID-19 cases

A Purdue University-affiliated startup is receiving national support to pursue a strategy to treat severe COVID-19 cases and possible future outbreaks involving other viruses.

27 Jan 2021

SARS-CoV-2 spike may impair antigen presentation by CD8 T cells

A new study published on the bioRxiv preprint server aims to identify specific viral epitopes on the spike protein from various regions of the spike protein and the T cell responses they evoke.

27 Jan 2021

Novel immunotherapy combination can be highly effective for treating lung cancer

McMaster University researchers have established in lab settings that a novel combination of two forms of immunotherapy can be highly effective for treating lung cancer, which causes more deaths than any other form of cancer.

27 Jan 2021

Iron-carrying extracellular vesicles promote viral-bacterial co-infection

The mechanism by which acute viral respiratory infections promote secondary bacterial growth and infection in the airways depends on iron-carrying extracellular sacs secreted by the cells lining the host's airways, report researchers from the University of Pittsburgh School of Medicine in a paper published today in Cell Reports.

26 Jan 2021

Two enzymes fuel transition from pre-cancer stem cells to leukemia stem cells

Since stem cells can continually self-regenerate, making more stem cells, and differentiate into many different specialized cell types, they play an important role in our development and health.

26 Jan 2021