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Non-coding RNA MALAT1 influences lung cancer metastasis

The vast majority - approximately 80 percent - of our DNA does not code for proteins, yet it gets transcribed into RNA. These RNA molecules are called non-coding and fulfill multiple tasks in the cell. Alongside a well-studied group of small RNAs, there is also a class of so-called long non-coding RNAs consisting of more than 200 nucleotides.

6 Feb 2013

Tenet completes $850 million Senior Secured Notes offering

Tenet Healthcare Corporation announced today the successful completion of its previously announced private offering of $850 million aggregate principal amount of its 4.50% Senior Secured Notes due 2021.

6 Feb 2013

Kips Bay Medical initiates eMESH I clinical feasibility trial in atherosclerotic disease

Manny Villafaña, Chairman and CEO of Kips Bay Medical Inc. announced that on February 5, 2013, the first U.S. patient was implanted with the eSVS Mesh at the Northeast Georgia Heart Center in Gainesville, Georgia.

6 Feb 2013

Insurance exchange 'navigators,' new payment models claim roles in health law implementation

The Washington Post reports on the challenges involved in fielding a team of health exchange navigators to help people work through their choices and the process. Meanwhile, MedPage Today reports on comments made by Health and Human Services Secretary Kathleen Sebelius regarding the "obligation" providers have to try new payment models.

5 Feb 2013

Patients with preinfarction angina have smaller heart attacks, improved cardiac function

Patients who experience chest pain in the 24 hours preceding a heart attack, also called preinfarction angina, have smaller heart attacks and improved cardiac function in the contemporary cardiac stenting era, researchers found in a study published Jan. 22 in Circulation: Cardiovascular Interventions.

5 Feb 2013

Mesa Laboratories third quarter revenues increase 18% to $11,361,000

Mesa Laboratories, Inc. today reported an 18 percent increase in revenues for the third quarter ended December 31, 2012.

5 Feb 2013

Viewpoints: Sen. Hatch's prescription for safeguarding entitlements; Medicare crackdown on CVS drug program; JFK's mental health vision failing

American families are used to working with dollar amounts starting with hundreds and thousands. But the fiscal situation of our country requires us to act in terms of billions and trillions. ... Unfortunately, waiting until the last minute to stop a crisis has become standard operating procedure in Washington. But that isn't how we should be tackling our debt or safeguarding Medicare and Medicaid.

5 Feb 2013

CT cancer risk small compared with underlying morbidity

The mortality risk associated with the underlying reason for computed tomography imaging in young adults outweighs the risk for radiation-induced cancer, reassure US researchers.

5 Feb 2013

Advanced care planning improves end-of-life care

Advance care planning for older adults results in improved quality of care at the end of life, with less in-hospital death and the increased use of hospice services, the results of a study indicate.

5 Feb 2013

Location of altered brain metabolite levels found in bipolar I patients

Bipolar I disorder patients have increased phospholipid levels in the thalami and increased N-acetyl-aspartate levels in the left hippocampus compared with healthy individuals, a team of investigators has discovered.

5 Feb 2013

Results from Merck’s Vorinostat phase 1 trial on lymphoma

Patients whose aggressive lymphomas have relapsed or failed to respond to the current front-line chemotherapy regimen now have an effective second line of attack against their disease.

5 Feb 2013

DCC receptor plays key role in regulating brain plasticity

Our ability to learn and form new memories is fully dependent on the brain's ability to be plastic - that is to change and adapt according to new experiences and environments. A new study from the Montreal Neurological Institute - The Neuro, McGill University, reveals that DCC, the receptor for a crucial protein in the nervous system known as netrin, plays a key role in regulating the plasticity of nerve cell connections in the brain.

5 Feb 2013

Risks and benefits of computed tomography in young adults

The underlying medical conditions facing young adults who undergo computed tomography (CT) exams represent a significantly greater health risk than that of radiation-induced cancer from CT, according to a new study published online in the journal Radiology.

5 Feb 2013

Vitamin C supplements increase risk of kidney stones in men

New research from Karolinska Institutet in Sweden shows that men who take vitamin C supplements regularly run a higher risk of developing kidney stones. The study, which is published in the scientific periodical JAMA Internal Medicine, did not however observe an increased risk between kidney stones and multivitamins - which contain lower concentrations of vitamin C.

5 Feb 2013

State roundup: Minn. officials want money for coverage expansion

Gov. Mark Dayton and his Human Services commissioner will travel to Washington, D.C., this week to lobby for federal money for MinnesotaCare. MinnesotaCare is a state-subsidized health plan that insures about 130,000 people under age 65. Dayton and Commissioner Lucinda Jesson are scheduled to meet Tuesday in Washington with Health and Human Services Secretary Kathleen Sebelius.

5 Feb 2013

Direct link between exposure to pesticides in food, air and water and prevalence of type 2 diabetes

A study led by the University of Granada reveals that there is a direct relationship between the presence of Persistent Organic Pollutants in the body and the development of type 2 diabetes, regardless of the patient's age, gender or body mass index.

5 Feb 2013

State officials, policy experts mull health law implementation issues

The Medicaid expansion continues to trigger significant debate and discussion among state officials.

5 Feb 2013

Water tubing-related injuries on the rise: Study

Water tubing, a recreational activity in which participants ride an inner tube which is pulled behind a boat by a tow rope, has grown in popularity in recent years. Unfortunately, the number of injuries related to this activity has also increased.

5 Feb 2013

ATI Neurostimulation System demonstrates clinical effectiveness in treating cluster headache

Autonomic Technologies, Inc. (ATI), the developer of the ATI Neurostimulation System designed for the treatment of severe headaches, today announced results of their clinical study in cluster headache, now published online in Cephalalgia.

5 Feb 2013

PET with 11C-PIB can positively visualize amyloid deposits in the heart

While amyloid imaging may now be most associated with detecting plaques in the brain, it has the potential to change the way cardiac amyloidosis is diagnosed. According to first-of-its-kind research published in the February issue of The Journal of Nuclear Medicine, positron emission tomography (PET) with 11C-PIB can positively visualize amyloid deposits in the heart.

5 Feb 2013