Transcription News and Research

RSS

Androgen receptors promote hepatitis B virus in growth and development of hepatoma cells

Dr. Ming-Heng Wu of the Institute of Basic Medical Sciences at National Cheng Kung University (NCKU), Taiwan, in collaboration with Prof. Chawnshang Chang's laboratory of University of Rochester (UR), United States, have discovered that androgen receptors (AR) can promote hepatitis B virus-induced hepatocarcinogenesis through modulation of hepatitis B virus (HBV) RNA transcription.

20 May 2010

MEDRAD's Intego PET Infusion System integrated with Pinestar's Nuclear Medicine Information System

Today, MEDRAD, Inc. and Pinestar Technology, Inc. announced plans to enable data communication between MEDRAD's Intego™ PET Infusion System and Pinestar's Nuclear Medicine Information System (NMIS). The companies are closing the information gap between state of the art infusion systems and the latest information systems, and thus adding to the workflow benefits of automated FDG infusion.

20 May 2010

Over-expression of Stat5 protein leads to deadly spread of prostate cancer: Study

Researchers from the Kimmel Cancer Center at Jefferson have found that Stat5, a signaling protein previously found to be key to survival of prostate cancer, is also involved in metastasis.

20 May 2010

Research team converts astroglia into two main classes of cortical neurons

The research team led by Professor Magdalena Götz of Helmholtz Zentrum München and Ludwig-Maximilians-Universität (LMU) Munich reports a major step forward in discovering a therapy for neurodegenerative diseases such as Alzheimer's or stroke. The researchers were able to convert glial cells of the brain into two different functional classes of neurons. The findings are published on May 18th in the renowned journal PLoS Biology.

19 May 2010

Research sheds light on early embryogenesis, genetic disease

Chromosome 22q11 deletion syndrome (also known as DiGeorge syndrome) is the most common human chromosome deletion syndrome, having an estimated incidence of at least one in 4,000 live births.

15 May 2010

RYGB surgery increases insulin activity in diabetes mellitus patients

Diabetes mellitus is a chronic metabolic disease resulted from, either decreased production of insulin or increased resistance to it from peripheral tissues or both factors combined together. While medical treatment remains the mainstay of treatment for diabetes, some surgical procedures, such as Roux-en-Y gastric bypass, have demonstrated some potential to be a treatment option for diabetes.

13 May 2010

Research sheds light on prenatal heart formation, chromosome 22q.11 deletion syndrome

Researchers studying the common genetic disorder chromosome 22q.11 deletion syndrome have identified key proteins that act together to regulate early embryonic development. One protein is essential to life; in animal studies, embryos without the protein do not survive past the first few days of gestation.

13 May 2010

Sanford-Burnham Scientific Symposium provides wealth of information on microRNAs, RNAi

Investigators from around the country came to Sanford-Burnham Medical Research Institute (Sanford-Burnham) on Friday, May 7, to share their knowledge of the burgeoning young field of microRNAs. These small non-coding nucleic acids turn off proteins and have been implicated in viral infection, cancer, cardiovascular disease, HIV and numerous other conditions.

12 May 2010

Researchers investigate aberrant expression of nuclear matrix proteins in gastric cancer cells

Gastric cancer is the most common malignant gastrointestinal cancer and accounts for 25% of cancer deaths. Nuclear matrix, a filamentous protein framework for eukaryotic cellular chromatin, closely relates to DNA duplication and transcription. Research on nuclear matrix proteins will provide insight into how tumors developed.

7 May 2010

Inadvertent reprogramming of genes in peripheral nervous system may cause chronic pain

Chronic pain severely limits patients' quality of life and is among the cost drivers in U.S. health care. Patients can suffer pain without an apparent cause and often fail to respond to available treatments. Mayo Clinic researchers and collaborators now report that chronic pain may be caused by the inadvertent reprogramming of more than 2,000 genes in the peripheral nervous system. The research findings appear in the current issue of the journal Genome Research.

7 May 2010

Bar-code eMAR combination of technologies reduce transcription, medication administration errors

Using bar-code technology with an electronic medication administration record (eMAR) substantially reduces transcription and medication administration errors, as well as potential drug-related adverse events, says a new study funded by HHS' Agency for Healthcare Research and Quality. The study is published in the May 6 issue of the New England Journal of Medicine.

6 May 2010

Genomic Health reports 22% revenue growth, 58% decrease in net loss for first-quarter 2010

Genomic Health, Inc. today reported financial results and business progress for the quarter ended March 31, 2010.

6 May 2010

Scientists develop new web-based algorithm techniques to identify DNA sequences

Life is almost unbearably complex. Humans and mice, frogs and flies toggle genes on and off in dizzying combinations and sequences during their relentless march from embryo to death. Now scientists seeking to understand the machinations of the proteins behind the genomic wizard's screen have a powerful new tool at their disposal, courtesy of researchers at the Stanford University School of Medicine.

5 May 2010

New treatments for intestinal failure, other intestinal absorption disorders

New treatments for intestinal failure and other intestinal absorption disorders are a step closer to the patients who need them after a discovery in Kelly Tappenden's University of Illinois laboratory.

5 May 2010

Deficiency of frataxin protein causes Friedreich's ataxia

The defective gene responsible for Friedreich's ataxia was identified over 20 years ago, but so far our ideas of how this gene causes the disease have been merely speculative. It was assumed that, as a result of the mutation, the gene could no longer be transcribed because this stretch of DNA was inaccessible. FMI Group Leader Marc Bühler and his team have now carried out experiments demonstrating that this is not the case and revealing what actually happens in Friedreich's ataxia.

4 May 2010

Study uncovers transcription control mechanism that is regulated by cancer-causing gene

A comprehensive new gene expression study in embryonic stem cells has uncovered a transcription control mechanism that is not only more pervasive than once thought but is also heavily regulated by the cancer-causing gene c-Myc.

30 Apr 2010

Study promises a new treatment for cancer

Cancer cells producing toxins that destroy tumours - could this be a future treatment for cancer? Researchers at Lund University have achieved good results in tests on both cells and animals.

30 Apr 2010

Emdat launches DaRT solution to help physicians utilize EMRs more efficiently

Emdat announces the launch of DaRT, or Discrete accurate Reportable Transcription, a solution that enables more efficient utilization of electronic medical records by seamlessly integrating with Emdat's online medical transcription platform.

29 Apr 2010

Combination of antibiotics can cure Chlamydia-induced ReA: Study

Researchers from University of South Florida College of Medicine found a combination of antibiotics to be an effective treatment for Chlamydia-induced reactive arthritis, a major step forward in the management, and possibly cure, of this disease. Results of this study are published in the May issue of Arthritis & Rheumatism, a journal of the American College of Rheumatology.

29 Apr 2010

Life Technologies debuts Invitrogen MAGic Sample Processor for addressing reproducibility challenges

Life Technologies Corporation today debuted the life science industry's first benchtop sample preparation system designed to increase productivity while eliminating manual and contamination-related challenges traditionally associated with protein and epigenetic protocols. The Invitrogen MAGic™ Sample Processor enables researchers to cut protocol time in half, dramatically reduce experimental errors, and perform technically challenging experiments in protein purification and epigenetics.

26 Apr 2010

Transcription News and Research

Androgen receptors promote hepatitis B virus in growth and development of hepatoma cells

MEDRAD's Intego PET Infusion System integrated with Pinestar's Nuclear Medicine Information System

Over-expression of Stat5 protein leads to deadly spread of prostate cancer: Study

Research team converts astroglia into two main classes of cortical neurons

Research sheds light on early embryogenesis, genetic disease

RYGB surgery increases insulin activity in diabetes mellitus patients

Research sheds light on prenatal heart formation, chromosome 22q.11 deletion syndrome

Sanford-Burnham Scientific Symposium provides wealth of information on microRNAs, RNAi

Researchers investigate aberrant expression of nuclear matrix proteins in gastric cancer cells

Inadvertent reprogramming of genes in peripheral nervous system may cause chronic pain

Bar-code eMAR combination of technologies reduce transcription, medication administration errors

Genomic Health reports 22% revenue growth, 58% decrease in net loss for first-quarter 2010

Scientists develop new web-based algorithm techniques to identify DNA sequences

New treatments for intestinal failure, other intestinal absorption disorders

Deficiency of frataxin protein causes Friedreich's ataxia

Study uncovers transcription control mechanism that is regulated by cancer-causing gene

Study promises a new treatment for cancer

Emdat launches DaRT solution to help physicians utilize EMRs more efficiently

Combination of antibiotics can cure Chlamydia-induced ReA: Study

Life Technologies debuts Invitrogen MAGic Sample Processor for addressing reproducibility challenges

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Latest News