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Study identifies 24 new copy number variants linked with autism

University of Utah (the U) researchers, in collaboration with several groups from around the country, published a paper on Monday, Jan. 14, 2013, following one of the biggest studies of its kind, that extends our understanding of genes related to autism spectrum diseases (ASDs) and advances methods for early detection and treatment.

16 Jan 2013

Hospital news: Nantucket's paradox; Maryland overbilling; Calif. fee complication

Nestled on an island 30 miles out to sea, Nantucket Cottage Hospital is the only rural hospital in Massachusetts, as defined by the federal government. Its weathered cedar shingles and widow's walk evoke the bygone era of its founding a century ago.

16 Jan 2013

New system based on photonic biosensors can rapidly diagnose food allergies

Researchers at the Institute of Materials Science of the Universitat de València, in consortium with various European companies and institutions, are developing a system based on photonic biosensors for rapid diagnosis of food allergies.

16 Jan 2013

Viewpoints: $4,000 a night for a 'cozy' hospital room; Texas effort to provide women's health care falls short

Call it the $55,000 cat bite. That's the rough total in medical costs (so far) for a cat bite on my hand that turned into an infection that turned into surgery that turned into a week in the hospital.

16 Jan 2013

CHOP to study antibiotic delivery to children after hospitalization for serious bacterial infection

The Children's Hospital of Philadelphia (CHOP) was awarded nearly $2M in research funding from the Patient-Centered Outcomes Research Institute (PCORI) to study antibiotic delivery to children returning home after hospitalization for a severe bacterial infection.

16 Jan 2013

Genetics researchers identify 25 additional copy number variations associated with autism

Genetics researchers have identified 25 additional copy number variations (CNVs)—missing or duplicated stretches of DNA—that occur in some patients with autism. These CNVs, say the researchers, are "high impact": although individually rare, each has a strong effect in raising an individual's risk for autism.

16 Jan 2013

Low birth weight does not increase risk of asthma in young children

Asthma is a serious condition that affects more than 25.7 million Americans, and is responsible for nearly 4,000 deaths annually. While the cause of asthma remains unknown, a study released today in the January issue of Annals of Allergy, Asthma and Immunology, the scientific journal of the American College of Allergy, Asthma and Immunology (ACAAI), has concluded that low birth weight is not associated with asthma risk in young children.

16 Jan 2013

p53 activation suppresses malic enzyme expression and leads to senescence in pre-cancerous cells

It is perhaps impossible to overstate the importance of the tumor suppressor gene p53. It is the single most frequently mutated gene in human tumors. p53 keeps pre-cancerous cells in check by causing cells, among other things, to become senescent - aging at the cellular level. Loss of p53 causes cells to ignore the cellular signals that would normally make mutant or damaged cells die or stop growing.

16 Jan 2013

TSC22D4 gene plays a key role in the onset of cachexia

Cachexia or wasting is a condition affecting up to 70 percent of cancer patients, depending on the type of cancer. It is characterized by a dramatic loss of body weight that is independent of food intake. Cachexia is seen particularly often and most pronounced in patients suffering from cancers of the digestive tract and the lungs.

16 Jan 2013

Functionally deaf patients can gain normal hearing with new implant that replaces the middle ear

Functionally deaf patients can gain normal hearing with a new implant that replaces the middle ear. The unique invention from the Chalmers University of Technology has been approved for a clinical study. The first operation was performed on a patient in December 2012.

15 Jan 2013

Study highlights the risk that female teenagers face when they go online

A new study highlights the risk that female teenagers face when they go online - a risk heightened for teen girls who have been victims of abuse or neglect.

15 Jan 2013

Novel system could allow broader screening for esophageal cancer, other conditions

Physicians may soon have a new way to screen patients for Barrett's esophagus, a precancerous condition usually caused by chronic exposure to stomach acid. Researchers at the Wellman Center for Photomedicine at Massachusetts General Hospital (MGH) have developed an imaging system enclosed in a capsule about the size of a multivitamin pill that creates detailed, microscopic images of the esophageal wall. The system has several advantages over traditional endoscopy.

15 Jan 2013

Children with chronic medical conditions more likely to use alternative medicine

Children who regularly see specialists for chronic medical conditions are also using complementary medicine at a high rate, demonstrates recently published research from the University of Alberta and the University of Ottawa.

15 Jan 2013

Aggressive breast cancer’s metastasis molecular switch identified

Scientists at Weill Cornell Medical College have discovered the molecular switch that allows aggressive triple negative breast cancer cells to grow the amoeba-like protrusions they need to crawl away from a primary tumor and metastasize throughout the body. Their findings, published in Cancer Cell, suggest a novel approach for developing agents to treat cancer once it has spread.

15 Jan 2013

Knee cartilage repair success with new biomaterial

In a small study, researchers reported increased healthy tissue growth after surgical repair of damaged cartilage if they put a “hydrogel” scaffolding into the wound to support and nourish the healing process. The squishy hydrogel material was implanted in 15 patients during standard microfracture surgery, in which tiny holes are punched in a bone near the injured cartilage. The holes stimulate patients’ own specialized stem cells to emerge from bone marrow and grow new cartilage atop the bone.

15 Jan 2013

Hospital News and Research

Study identifies 24 new copy number variants linked with autism

Hospital news: Nantucket's paradox; Maryland overbilling; Calif. fee complication

New system based on photonic biosensors can rapidly diagnose food allergies

Viewpoints: $4,000 a night for a 'cozy' hospital room; Texas effort to provide women's health care falls short

CHOP to study antibiotic delivery to children after hospitalization for serious bacterial infection

Genetics researchers identify 25 additional copy number variations associated with autism

Low birth weight does not increase risk of asthma in young children

p53 activation suppresses malic enzyme expression and leads to senescence in pre-cancerous cells

TSC22D4 gene plays a key role in the onset of cachexia

Functionally deaf patients can gain normal hearing with new implant that replaces the middle ear

Study highlights the risk that female teenagers face when they go online

Novel system could allow broader screening for esophageal cancer, other conditions

Children with chronic medical conditions more likely to use alternative medicine

Aggressive breast cancer’s metastasis molecular switch identified

Knee cartilage repair success with new biomaterial

Hearing loss with radiotherapy for head and neck tumors

Dizziness does not hamper neck pain therapy

Pediatric CKD rates increase substantially in south of England

Sexual dysfunction not determined by hysterectomy technique

Emergency departments drained of resources for elderly

Improving healthcare sustainability through carbon data

Managing vibration in IVF laboratories

A New Approach to Preventing Bladder Cancer Recurrence

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