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Positive results from NanoString's second clinical study of PAM50-based breast cancer assay

NanoString Technologies, Inc., a privately held provider of life science tools for translational research and developer of molecular diagnostic products, today announced positive results from the second clinical validation study of its in vitro diagnostic breast cancer assay based on the PAM50 gene expression signature.

From NanoString Technologies 7 Dec 2012

Advance Study to evaluate safety and benefit of DBS-f for patients with mild Alzheimer's

The first U.S. patient to enroll in Functional Neuromodulation's ADvance Study was successfully implanted with a deep brain stimulation (DBS) system. ADvance will evaluate the safety and potential clinical benefit of DBS of the fornix (DBS-f), a major inflow and output pathway in the brain's memory circuit, for patients with mild Alzheimer's.

7 Dec 2012

Scientists isolate previously unknown protein in skeletal muscle

Scientists at Dana-Farber Cancer Institute have isolated a previously unknown protein in muscles that spurs their growth and increased power following resistance exercise. They suggest that artificially raising the protein's levels might someday help prevent muscle loss caused by cancer, prolonged inactivity in hospital patients, and aging.

7 Dec 2012

People with glaucoma show delayed eye movement reaction times

Rapid eye movements are significantly delayed in patients with glaucoma, even those in the early stages of the disease, research has found.

7 Dec 2012

Microarray analysis more effective in pinpointing potential genetic causes of stillbirth

Stillbirth is a tragedy that occurs in one of every 160 births in the United States. Compounding the sadness for many families, the standard medical test used to examine fetal chromosomes often can't pin down what caused their baby to die in utero. In most cases, the cause of the stillbirth is not immediately known.

6 Dec 2012

Children with snoring or apnea have concurrent behavioral sleep problems

Children with sleep-related breathing problems (such as snoring or apnea) frequently have concurrent behavioral sleep problems (such as waking repeatedly) - and vice versa, according to research led by a scientist at Albert Einstein College of Medicine of Yeshiva University.

6 Dec 2012

Roundup: Fla. judge rules legislature must decide on prison care privatization; Skepticism over Ore. medical liability reform proposal

A Tallahassee judge ruled Tuesday that a legislative committee did not have the authority to approve a contract regarding prison health care services. According to Businessweek, the plan would privatize health care services in three of Florida's four prison system regions. Circuit Judge John Cooper, who made the decision, said the policy changes must be approved by the full Legislature, rather than just a panel of 14 select legislators.

6 Dec 2012

FDA designates two of Cubist’s Phase 3 antibiotic candidates

Cubist Pharmaceuticals, Inc. today announced that the U.S. Food and Drug Administration (FDA) has designated two of the company's Phase 3 antibiotic candidates, CXA-201 (ceftolozane/tazobactam) and CB-315, as Qualified Infectious Disease Products (QIDP).

6 Dec 2012

Scientists identify key molecular pathway that leads to depression

Scientists have identified the key molecular pathway leading to depression, revealing potential new targets for drug discovery, according to research led by King's College London's Institute of Psychiatry. The study, published today in Neuropsychopharmacology, reveals for the first time that the 'Hedgehog pathway' regulates how stress hormones, usually elevated during depression, reduce the number of brain cells.

6 Dec 2012

IASIS Healthcare fourth quarter net revenue decreases 2.2% to $633.0 million

IASIS Healthcare LLC, today announced financial and operating results for the fiscal fourth quarter and year ended September 30, 2012.

6 Dec 2012

UC San Diego Health System receives Comprehensive Stroke Center designation

UC San Diego Medical Center-Hillcrest is one of five facilities in the country, and the only center in San Diego County, to be recognized as one of the first Comprehensive Stroke Centers (CSC), the newest level of certification for advanced stroke care awarded by The Joint Commission.

6 Dec 2012

First Edition: December 6, 2012

Today's headlines include a report that some in the GOP are urging lawmakers to support the idea of trading tax breaks for changes in safety-net programs.

6 Dec 2012

Prenatal stress linked to affective disorders in offspring

Individuals born to women who experience major stress during early pregnancy are at increased risk for developing affective disorders, study results suggest.

6 Dec 2012

Fexinidazole enters Phase II/III clinical study to treat sleeping sickness

A new oral-only treatment for sleeping sickness has entered Phase II/III clinical study in patients with late-stage sleeping sickness in the Democratic Republic of the Congo (DRC) and soon in Central African Republic (CAR).

6 Dec 2012

North Shore-LIJ, VA open Unified Behavioral Health Center for Military Veterans and Their Families

Representatives from the US Department of Veterans Affairs (VA), the North Shore-LIJ Health System and local veterans today celebrated the opening of the Unified Behavioral Health Center for Military Veterans and Their Families, a first-of-its-kind facility designed to help military families cope with the emotional burdens veterans frequently face after returning home from combat.

6 Dec 2012

Using Nanoparticles to Target Cancer

An interview with John Stroh, discussing the development of nanoparticles that can target and treat cancer, without damaging nearby tissues.

6 Dec 2012

SLN surgery identifies whether breast cancer in lymph nodes remains after chemotherapy

Most patients whose breast cancer has spread to their lymph nodes have most of the lymph nodes in their armpit area removed after chemotherapy to see if any cancer remains. A study conducted through the American College of Surgeons Oncology Group and led by Judy Boughey, M.D. a breast surgeon at Mayo Clinic shows that a less invasive procedure known as sentinel lymph node surgery successfully identified whether cancer remained in lymph nodes in 91 percent of patients with node-positive breast cancer who received chemotherapy before their surgery.

6 Dec 2012

UnitedHealth report examines how doctors get paid

A new report from UnitedHealth Group Inc. takes aim at the way U.S. doctors get paid, saying the nation could save up to $1 trillion over the next decade in health care costs if it were possible to "unleash the potential of payment reform initiatives."

6 Dec 2012

New technology allows noninvasive SpHb assessments for children undergoing brain surgery

For children undergoing brain surgery, a new technology allows noninvasive, continuous monitoring of blood hemoglobin levels, according to a study in the December issue of Anesthesia & Analgesia, official journal of the International Anesthesia Research Society (IARS).

6 Dec 2012

Alcoholics Anonymous helps men and women maintain sobriety in different ways

A new study finds differences in the ways that participation in Alcoholics Anonymous (AA) helps men and women maintain sobriety. Two Massachusetts General Hospital (MGH) investigators found that, while many factors are helpful to all AA participants, some were stronger in men and some in women.

6 Dec 2012