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A comprehensive rule book for the design of safe and efficient therapeutic cells

Therapies based on engineered immune cells have recently emerged as a promising approach in the treatment of cancer.

15 Apr 2022

Breakthrough finding reveals how male sex hormones contribute to cancer-related sex bias

Patients with cancers stemming from non-reproductive organs, such as bladder and liver cancer, have striking discrepancies in incidence, progression, response to treatment and survival outcomes depending on their sex. In almost all cases, male patients have worse prognoses and outcomes.

15 Apr 2022

How the test-to-treat pillar of the US covid strategy is failing patients

The federal "test-to-treat" program, announced in March, is meant to reduce covid hospitalizations and deaths by quickly getting antiviral pills to people who test positive. But even as cases rise again, many Americans don't have access to the program.

15 Apr 2022

Insight into the future of genetic testing

In this interview, we speak to Sheetal Parmar, vice president of medical affairs and head of clinical services at Natera, about their cell-free DNA (cfDNA) testing services.

From Natera 15 Apr 2022

Comparison of breakthrough infections in healthcare workers between 3 and 4-dose BNT162b2 vaccine recipients

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15 Apr 2022

Researchers track COVID-fighting antibodies after vaccination

The antibodies generated by Pfizer's COVID-19 vaccine rise more slowly and decline more quickly than those generated by the Moderna vaccine, according to a new study from UVA Health.

15 Apr 2022

COVID-19 vaccine offers protection for pregnant women and newborns

Pregnant women continue to have reservations about getting vaccinated against COVID-19 despite research indicating the safety of the vaccines and the protection they may offer their unborn children.

15 Apr 2022

Effects of COVID-19 treatment best with combination therapy

There is a steadily growing arsenal of drugs for COVID-19. Researchers from Charité – Universitätsmedizin Berlin, the Max Delbrück Center for Molecular Medicine (MDC) and Freie Universität (FU) Berlin have studied the mechanisms of action of antiviral and anti-inflammatory drugs.

15 Apr 2022

Cell’s production of lipids can be a key factor in determining cell fate

How does a cell "decide" what type of cell to become? The question of "cell fate" has been explored for decades now, especially in the context of stem cell biology, but there are still gaps in our understanding.

15 Apr 2022

Acute stroke associated with considerable loss in life expectancy

Almost two-thirds of acute stroke patients fail to survive more than a decade and have high risk of recurrence, prompting researchers to call for better patient care.

15 Apr 2022

New study paves the way for first drug treatment for sleep apnea

A new University of Gothenburg study has paved the way for the first drug treatment for sleep apnea. Compared to before receiving the treatment, breathing pauses decreased with on average more than 20 per hour for patients given the drug.

15 Apr 2022

New short-course treatment effective against HIV-associated cryptococcal meningitis

A new short-course treatment is effective against HIV-associated cryptococcal meningitis with fewer serious side effects, and has the potential to reduce the length and cost of hospital admissions, a study shows.

15 Apr 2022

Study finds racial and ethnic disparities in telemedicine uptake during the pandemic

Historical data shows minorities have long faced obstacles to getting the critical health care services they need. When COVID-19 arrived two years ago, telemedicine emerged with the promise of better access to care through virtual delivery of clinical services and consultations.

14 Apr 2022

Inhibiting key signaling pathway in immune cells may slow down Alzheimer's disease

Inhibiting an important signaling pathway in brain-resident immune cells may calm brain inflammation and thereby slow the disease process in Alzheimer's and some other neurodegenerative diseases, suggests a study by Weill Cornell Medicine investigators.

14 Apr 2022

Yale research demonstrates the cancer relevance of known human genes

Following an analysis of over 12,000 human genes, research from Yale Cancer Center indicates there is cancer-relevant importance in a much larger proportion of human genes than current cancer research models suggest.

14 Apr 2022

Brown adipose tissue is less active in boys with obesity, study finds

A study at McMaster University has found that brown adipose tissue (BAT) is less active in boys with obesity compared to boys with a normal body mass index (BMI).

14 Apr 2022

Chronic tiredness in people with sleep apnea can have serious implications for road safety

Up to half of older adults may have sleep apnea, a condition in which breathing and sleep are briefly interrupted many times a night.

14 Apr 2022

Scientists discover differences in interaction of T-cells within tumor microenvironments

A team led by Northwestern Medicine investigators has discovered differences in the distribution and interaction of T-cells within the microenvironment of different regions of both brain tumors and brain metastases, according to findings published in the journal JCI Insight.

14 Apr 2022

Booster dose of mRNA vaccine highly effective in preventing SARS-CoV-2 infection

A booster dose of mRNA vaccine significantly decreases the risk of being infected with either the delta or omicron COVID-19 variants, according to scientists at the Rocky Mountain Center for Occupational and Environmental Health (RMCOEH), a program partnership between the University of Utah and Weber State University.

14 Apr 2022

New data-driven mechanistic approach can help reduce drug costs and treat diseases

A new data-driven mechanistic approach that predicts cell types within tissue will help to reduce drug costs and treat diseases that were difficult to develop drugs for, according to a West Virginia University scientist.

14 Apr 2022

Research News and Research

A comprehensive rule book for the design of safe and efficient therapeutic cells

Breakthrough finding reveals how male sex hormones contribute to cancer-related sex bias

How the test-to-treat pillar of the US covid strategy is failing patients

Insight into the future of genetic testing

Comparison of breakthrough infections in healthcare workers between 3 and 4-dose BNT162b2 vaccine recipients

Researchers track COVID-fighting antibodies after vaccination

COVID-19 vaccine offers protection for pregnant women and newborns

Effects of COVID-19 treatment best with combination therapy

Cell’s production of lipids can be a key factor in determining cell fate

Acute stroke associated with considerable loss in life expectancy

New study paves the way for first drug treatment for sleep apnea

New short-course treatment effective against HIV-associated cryptococcal meningitis

Study finds racial and ethnic disparities in telemedicine uptake during the pandemic

Inhibiting key signaling pathway in immune cells may slow down Alzheimer's disease

Yale research demonstrates the cancer relevance of known human genes

Brown adipose tissue is less active in boys with obesity, study finds

Chronic tiredness in people with sleep apnea can have serious implications for road safety

Scientists discover differences in interaction of T-cells within tumor microenvironments

Booster dose of mRNA vaccine highly effective in preventing SARS-CoV-2 infection

New data-driven mechanistic approach can help reduce drug costs and treat diseases

New Approach Methodologies, the 3Rs and Multimodal Imaging in Preclinical Research - eBook eBook

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