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Therapies for LGL leukemia should target the immune system, not only cancer cells

An international study coordinated by a University of Helsinki research group demonstrates that the body's immune system attacks itself in a rare type of blood cancer.

11 Apr 2022

Study identifies several therapeutically effective drugs for bladder cancer

Hundreds of chemical compounds were screened on cell cultures representing different stages and subtypes of bladder cancer and several promising agents with inhibitory (growth-inhibiting) effects were identified.

11 Apr 2022

Drugs targeting DNA damage response pathway show therapeutic potential against advanced solid tumors

Results from early-stage clinical trials show two drugs that target the DNA damage response (DDR) pathway in cancers - ATR inhibitor elimusertib and PARP inhibitor AZD5305 - are safe and clinically beneficial in treating patients with advanced solid tumors.

11 Apr 2022

Patients with allergic disorders have greater risk of high blood pressure and coronary heart disease

Data from the National Health Interview Survey demonstrated adults with a history of allergic disorders have an increased risk of high blood pressure and coronary heart disease, with the highest risk seen in Black male adults.

11 Apr 2022

The relationship between household type, COVID-19 and mental health

Researchers demonstrated the relationship between the built environment with a common element and coronavirus disease 2019 (COVID-19) transmission and mental health conditions.

11 Apr 2022

Study finds molecular features responsible for the development of metastatic breast cancer

Susana Garcia-Recio, PhD, a research associate in the lab of Charles M. Perou, PhD, at UNC Lineberger Comprehensive Cancer Center, will present findings that identified molecular features responsible for the development and progression of metastatic breast cancer at the 2022 American Association for Cancer Research annual meeting. (Presentation: Abstract LB176/4, Tuesday, April 12, 3:20 p.m. ET, Room 217-219, Ernest N. Morial Convention Center in New Orleans.)

11 Apr 2022

Discovery of key regulator of body weight could lead to new treatments for metabolic disorders

Yale scientists uncover key regulator of body weight. Yale scientists have discovered that a protein known as augmentor-alpha regulates body weight in mice, an insight that could lead to new treatments for metabolic disorders.

11 Apr 2022

UMass Amherst-based COVID-19 Forecast Hub generates accurate predictions of pandemic deaths

The University of Massachusetts Amherst-based U.S. COVID-19 Forecast Hub, a collaborative research consortium, has generated the most consistently accurate predictions of pandemic deaths at the state and national level, according to a paper published April 8 in the Proceedings of the National Academies of Sciences.

11 Apr 2022

Sex-specific guidelines needed for treating obesity, hypertension and diabetes in women

Academic researchers are calling for new healthcare guidelines for treating obesity, hypertension and diabetes in women. Currently, there are no sex-specific guidelines for treating or preventing these health conditions, potentially limiting the medical care available to women.

11 Apr 2022

Alternative anti-HIV strategy generates promising results in a phase I clinical trial

vaccines against the virus, but unfortunately, HIV has numerous defense mechanisms that prevent a person's immune system from mounting an effective response following HIV vaccination.

11 Apr 2022

Novel strategy can shrink tumors and prolong survival in mice

A research team based at the University of Ottawa and The Ottawa Hospital has developed a virus that infects and kills cancer cells without harming normal cells, while also sending out signals to prepare nearby uninfected cancer cells for viral attack.

11 Apr 2022

Evidence of an increased risk of neurodegeneration after SARS-CoV-2 infection

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11 Apr 2022

New study reveals oral opaganib's potent in vitro activity against Omicron

RedHill Biopharma Ltd., a specialty biopharmaceutical company, today announced study results in which opaganib (ABC294640), a leading oral drug candidate for hospitalized patients with moderate to severe COVID-19, was observed to have potent in vitro efficacy against the Omicron SARS-CoV-2 variant, while maintaining host cell viability.

11 Apr 2022

Study finds higher risk of all-cause mortality among pediatric cancer patients in LMICs during the pandemic

During the first nine months of the COVID-19 pandemic, pediatric cancer patients from lower- and middle-income countries faced a higher risk of all-cause mortality than those in high-income countries, according to data presented at the AACR Annual Meeting 2022, held April 8-13.

11 Apr 2022

The Mount Sinai Hospital completes full renovation of its children's ED

The Mount Sinai Hospital has announced the completion of a full renovation of its children's Emergency Department (ED), and a newly redesigned area for walk-in, low acuity adult patients.

11 Apr 2022

Tobacco use increased in smokers trying to quit during COVID-19, study finds

While smoking rates have declined dramatically in the United States, there are still 35 million smokers. There are few data about whether, and if so, how current cigarette smoking habits among those trying to quit are affected by the COVID-19 pandemic.

11 Apr 2022

Research News and Research

Therapies for LGL leukemia should target the immune system, not only cancer cells

Study identifies several therapeutically effective drugs for bladder cancer

Drugs targeting DNA damage response pathway show therapeutic potential against advanced solid tumors

Patients with allergic disorders have greater risk of high blood pressure and coronary heart disease

The relationship between household type, COVID-19 and mental health

Study finds molecular features responsible for the development of metastatic breast cancer

Discovery of key regulator of body weight could lead to new treatments for metabolic disorders

UMass Amherst-based COVID-19 Forecast Hub generates accurate predictions of pandemic deaths

Sex-specific guidelines needed for treating obesity, hypertension and diabetes in women

Alternative anti-HIV strategy generates promising results in a phase I clinical trial

Novel strategy can shrink tumors and prolong survival in mice

Evidence of an increased risk of neurodegeneration after SARS-CoV-2 infection

New study reveals oral opaganib's potent in vitro activity against Omicron

Study finds higher risk of all-cause mortality among pediatric cancer patients in LMICs during the pandemic

The Mount Sinai Hospital completes full renovation of its children's ED

Tobacco use increased in smokers trying to quit during COVID-19, study finds

Millions of people face a postcode lottery to access fertility freezing treatments

Nanocell COVID-19 vaccine elicits potent neutralizing response

Age and higher ferritin levels associated with more severe MIS-C

Chromatin accessibility as an early marker of severe COVID-19

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