Small Intestine News and Research

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Researchers reveal how dietary intervention can help prevent autoimmune disease in mice

Could a change in diet be beneficial to people with autoimmune diseases such as lupus? A Yale-led team of researchers have revealed how a dietary intervention can help prevent the development of this autoimmune disease in susceptible mice.

21 Dec 2018

Lower BMI before obesity surgery predicts greater post-operative weight loss, study finds

Lower BMI before bariatric surgery predicts greater post-operative weight loss, a new study from the University of Eastern Finland finds.

11 Dec 2018

Gut protein mutations protect against spikes in blood glucose levels

Why is it that, despite consuming the same number of calories, sodium and sugar, some people face little risk of diabetes or obesity while others are at higher risk? A new study by investigators at Brigham and Women's Hospital has uncovered mutations in a gene that appear to help drive this difference.

21 Nov 2018

Live probiotics can change existing gut flora and alter immune response

New research published in the International Journal of Pharmaceutics demonstrates that 'good' bacteria in the live probiotic SymproveTM can successfully reach and colonize the gut, where they go on to change the existing gut flora. They are also capable of modifying immune response.

20 Nov 2018

New research project to combat obesity, type 2 diabetes receives NIH funding

A research project headed by a faculty member from the Ohio University Heritage College of Osteopathic Medicine, which will explore whether administering a protein that's produced in the body can help prevent obesity and type 2 diabetes, has received $464,145 in funding from the National Institutes of Health.

20 Nov 2018

Researchers discover key factors behind intestinal inflammation in CVID patients

Oregon State University researchers have discovered two key factors behind the intestinal inflammation that plagues people suffering from a disorder that affects their immune system.

14 Nov 2018

Researchers use MRI to watch how electrical stimulation could cure gastrointestinal disorders

More than 60 million people in the U.S. suffer from disorders in the gastrointestinal tract that could be cured by electrical stimulation, but scientists don't fully understand the therapy's effects on a critical organ: the stomach.

25 Oct 2018

Combination of Opdivo and Yervoy shows four-year survival benefits in patients with advanced melanoma

Bristol-Myers Squibb Company today announced four-year data from the Phase 3 CheckMate -067 clinical trial - the longest follow-up to date - which continues to demonstrate durable, long-term survival benefits with the first-line combination of Opdivo (nivolumab) and Yervoy (ipilimumab), versus Yervoy alone, in patients with advanced melanoma.

22 Oct 2018

Lab study shows effectiveness of potential therapy for treatment-resistant hypothyroidism

A new "metal-coordinated" drug-delivery technology potentially could be used to supplement the standard therapy for hypothyroidism, which affects nearly 10 million Americans, and many more patients worldwide, according to results of a study published in the journal Thyroid this month.

15 Oct 2018

Study reveals factors linked to the development of Crohn's disease

How cells talk to each other, and what they say, has long held fascination for Seema Khurana, professor of biology and biochemistry.

5 Oct 2018

New ReFRAME drug repurposing collection offers hope for treating major diseases

Each year, millions of people worldwide suffer from potentially fatal infectious diseases that often leave survivors facing a lifetime of related health problems. But what if drugs against such diseases already existed but nobody knew it?

4 Oct 2018

Protective gel sphere may offer probiotics a safer route to the intestines

The small intestine is a hotbed of microbial activity and a target of probiotic treatments for diarrhea, inflammatory bowel disease and irritable bowel syndrome, among other conditions.

26 Sep 2018

Toxicological evaluation and dosimetry estimation of potential PET radiotracer

The SR101 N-(3-[18F]Fluoropropyl) sulfonamide ([18F]SRF101) is a Sulforhodamine 101 derivative that was previously synthesized by our group.

25 Sep 2018

Research examines taste and odor preferences in patients after Roux-en-Y gastric bypass

Following Roux-en-Y gastric bypass, a type of bariatric surgery, many patients exhibit a reduction in taste preference for sweet and fatty foods, although this effect may only be temporary, according to new research from Binghamton University, State University of New York.

17 Sep 2018

Researchers find bacterial DNA in intestine of newborn calves

Researchers at the University of Helsinki, Finland have found bacterial DNA in the intestine of newborn calves, representing quite a diverse variety of bacterial species.

6 Sep 2018

Bile acids reduce desire for cocaine, finds study

Bile acids -- gut compounds that aid in the digestion of dietary fats -- reduce the desire for cocaine, according to a new study by researchers at Vanderbilt University Medical Center and the University of Alabama at Birmingham.

31 Aug 2018

Gut microbial signature may help identify causes of chronic malnutrition in children

Chronic malnutrition, usually associated with an inflammation of the small intestine, affects one in every four children under the age of five. It is the leading cause of child mortality in low-income countries and is also responsible for severe stunting.

24 Aug 2018

Fracture risk increases by 30% after gastric bypass, study shows

A study published in the Journal of Bone and Mineral Research shows that the risk of fractures increases by about 30 percent after a gastric bypass operation. It was also discovered that falls increase after these operations.

13 Aug 2018

Proof-of-concept technology using nanoparticles could offer new approach for oral medications

Since the development of insulin to manage diabetes, pharmacists have longed to create an insulin pill. Past attempts have failed because insulin does not survive the harsh conditions of the gastro-intestinal system and cannot easily cross the GI wall.

9 Aug 2018

Study suggests link between probiotic use and “brain fogginess”

A study conducted at the Medical College of Georgia at Augusta University has shown that probiotic intake can result in a significant build-up of small intestine bacteria that leads to brain fogginess.

8 Aug 2018