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Scientists take first steps to create neural-like stem cells from muscle tissue

Scientists at Wake Forest Baptist Medical Center have taken the first steps to create neural-like stem cells from muscle tissue in animals.

15 Oct 2012

Downregulated protein could be revascularization target in critical limb ischemia

Levels of calcium-sensor protein, S100A1, are downregulated in patients with critical limb ischemia, say researchers who believe the protein could be a potential therapeutic target to promote revascularization.

12 Oct 2012

Investigators provide overview of role of dopamine in modulating the immune system

Dopamine is a neurotransmitter that is associated with emotions, movement, and the brain's pleasure and reward system. In the current issue of Advances in Neuroimmune Biology, investigators provide a broad overview of the direct and indirect role of dopamine in modulating the immune system and discuss how recent research has opened up new possibilities for treating diseases such as Parkinson's and Alzheimer's disease, schizophrenia, multiple sclerosis or even the autoimmune disorders.

11 Oct 2012

Inpeco, Precise Biometrics partner to deploy Precise Match-on-Card technology

Precise Biometrics announces today that they have partnered with the Inpeco Group for a 6-month contract, to deploy Precise Match-on-Card technology to the Inpeco Group System.

11 Oct 2012

PARP-1 plays a major role in controlling AR function in prostate cancer patients

A newly discovered function of PARP-1 could be the key to more effective therapeutics to treat advanced prostate cancer patients, a recent preclinical study published in Cancer Discovery by Jefferson's Kimmel Cancer Center researchers suggests.

10 Oct 2012

RMND1 gene mutations responsible for severe neurodegenerative disorders

Scientists at the Montreal Neurological Institute and Hospital - The Neuro, McGill University working with a team at Oxford University have uncovered the genetic defect underlying a group of rare genetic disorders.

10 Oct 2012

New data from Genzyme's AUBAGIO and LEMTRADA clinical trials to be presented at ECTRIMS

Genzyme, a Sanofi company, announced today new data from Genzyme's clinical development programs for AUBAGIO (teriflunomide) and LEMTRADATM (alemtuzumab) will be presented at the 28th Congress of the European Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS) in Lyon, France, October 10-13.

9 Oct 2012

Nelfinavir inhibits growth of HER2-positive tumors

The HIV protease inhibitor, Nelfinavir, can be used to treat HER2-positive breast cancer in the same capacity and dosage regimen that it is used to treat HIV, according to a study published October 5 in the Journal of the National Cancer Institute.

6 Oct 2012

Improved small animal Positron Emission Tomography (PET) scanners introduced by IntelLiDrives

In research into human diseases and the search for potential treatments, small animal models play an important role in bridging the gap between in vitro and in vivo studies. IntelLiDrive is at the forefront of small animal PET tomography scanner design.

5 Oct 2012

Assisted reproduction technology may increase risk of MS activity among women

Researchers in Argentina report that women with multiple sclerosis (MS) who undergo assisted reproduction technology (ART) infertility treatment are at risk for increased disease activity.

4 Oct 2012

InterMune receives Health Canada approval for Esbriet to treat idiopathic pulmonary fibrosis

InterMune, Inc. today announced that Health Canada has approved Esbriet (pirfenidone) for the treatment of mild to moderate idiopathic pulmonary fibrosis (IPF) in adult patients.

3 Oct 2012

Five researchers receive IOF Young Investigator Awards

Five researchers were presented with 'IOF Young Investigator Awards' at the International Osteoporosis Foundation (IOF) Regionals - 2nd Middle East & Africa Osteoporosis Meeting and the 6th Pan Arab Osteoporosis Congress PAOC'6 on September 30, 2012.

2 Oct 2012

Hormone and androgen receptor genes combined affect sperm motility

The combination of alleles for genes encoding the follicle-stimulating hormone receptor and androgen receptor has a significant impact on sperm motility, emphasising the importance of the genes in sperm quality, say Greek scientists.

1 Oct 2012

PLOS ONE journal releases report on validation of Falcon Genomics' Cancer BioChip System

The online journal PLOS ONE released a scientific report on the validation of Falcon Genomics' Cancer BioChip System (CBCS) as a tool for identifying inhibitors of breast cancer.

29 Sep 2012

Hip arthroscopy system launched by DePuy Mitek

DePuy Mitek, Inc., a leading developer and manufacturer of orthopaedic sports medicine products and soft tissue repair devices, announced the launch of ENDURANCE Hip Solutions, a new system of instruments and devices that marks the company’s entry into the rapidly growing field of hip arthroscopy.

28 Sep 2012

Elevated c-Myc expression amplifies gene activity in tumor cells of multiple cancer types

For a cancer patient, over-expression of the MYC oncogene is a bad omen. Scientists have long known that in tumor cells, elevated levels of MYC's protein product, c-Myc, are associated with poor clinical outcomes, including increased rates of metastasis, recurrence, and mortality. Yet decades of research producing thousands of scientific papers on the subject have failed to consistently explain precisely how c-Myc exerts its effects across a broad range of cancer types. Until now, that is.

28 Sep 2012

Conditionally reprogrammed cells help identify effective therapy for HPV-positive RRP

Using a newly discovered cell technology, Georgetown University Medical Center researchers were able to identify an effective therapy for a patient with a rare type of lung tumor. The single case study, reported in the September 27 issue of New England Journal of Medicine, provides a snapshot of the new technology's promising potential; however, researchers strongly caution that it could be years before validation studies are completed and regulatory approval received for its broader use.

28 Sep 2012

k-MITOMI device can simultaneously measure up to 768 biomolecular interactions

Inside our cells, molecules are constantly binding and separating from one another. It's this game of constant flux that drives gene expression asides essentially every other biological process.

26 Sep 2012

Wiley announces publication of 6-volume Encyclopedia of Drug Metabolism and Interactions

Wiley is pleased to announce publication of the state-of-the-art, 6-volume Encyclopedia of Drug Metabolism and Interactions.

25 Sep 2012

PAM50 potentially simplifies underlying breast tumor biology

On September 23, researchers published online in the journal Nature a study of the molecular biology of breast cancer, using the intrinsic subtypes as defined by the PAM50 gene signature as an organizing framework for analyzing genomic and proteomic aberrations. This landmark study both underscores the emergence of the intrinsic subtypes as a powerful taxonomy of breast cancer in research, and PAM50's role as the gold standard for categorizing breast cancer by subtype.

From NanoString Technologies 25 Sep 2012

in vitro News and Research

Scientists take first steps to create neural-like stem cells from muscle tissue

Downregulated protein could be revascularization target in critical limb ischemia

Investigators provide overview of role of dopamine in modulating the immune system

Inpeco, Precise Biometrics partner to deploy Precise Match-on-Card technology

PARP-1 plays a major role in controlling AR function in prostate cancer patients

RMND1 gene mutations responsible for severe neurodegenerative disorders

New data from Genzyme's AUBAGIO and LEMTRADA clinical trials to be presented at ECTRIMS

Nelfinavir inhibits growth of HER2-positive tumors

Improved small animal Positron Emission Tomography (PET) scanners introduced by IntelLiDrives

Assisted reproduction technology may increase risk of MS activity among women

InterMune receives Health Canada approval for Esbriet to treat idiopathic pulmonary fibrosis

Five researchers receive IOF Young Investigator Awards

Hormone and androgen receptor genes combined affect sperm motility

PLOS ONE journal releases report on validation of Falcon Genomics' Cancer BioChip System

Hip arthroscopy system launched by DePuy Mitek

Elevated c-Myc expression amplifies gene activity in tumor cells of multiple cancer types

Conditionally reprogrammed cells help identify effective therapy for HPV-positive RRP

k-MITOMI device can simultaneously measure up to 768 biomolecular interactions

Wiley announces publication of 6-volume Encyclopedia of Drug Metabolism and Interactions

PAM50 potentially simplifies underlying breast tumor biology

Why use light scattering to analyze proteins and viral vectors?

Changing the landscape of R&D to build clinical success from the ground up

Sensing a Healthier Future

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