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Zinc sparks help doctors choose best eggs to transfer during IVF

A stunning explosion of zinc fireworks occurs when a human egg is activated by a sperm enzyme, and the size of these "sparks" is a direct measure of the quality of the egg and its ability to develop into an embryo, according to new research from Northwestern Medicine.

26 Apr 2016

New blood treatment technology could reduce malaria risk following blood transfusions

Patients, especially children, who undergo blood transfusions in sub-Saharan Africa are at high risk of transfusion-transmitted malaria. A new trial, published in The Lancet today, suggests that treating donated blood with a new technology that combines UV radiation and vitamin B is safe and could minimise the risk of malaria infection following blood transfusions.

26 Apr 2016

Study finds links between phthalate exposure and obesity

Exposure to chemicals found in everyday products could affect the amount of fat stored in the body, according to a study by University of Georgia researchers.

21 Apr 2016

Reducing hair loss during chemotherapy: an interview with Richard Paxman

The basic principle of chemotherapy is to damage the mitotic and metabolic processes in the cancer cells. The chemotherapy doesn't just target the cancer cells, it also targets the healthy cells, specifically ones that are rapidly dividing - our hair follicles are also rapidly dividing. We see damage to those hair cells, which then causes the hair to fall out.

From Paxman 19 Apr 2016

Scientists find way to control behaviour of cardiomyocytes using laser radiation

Scientists from MIPT's Laboratory of the Biophysics of Excitable Systems have discovered how to control the behaviour of heart muscle cells (cardiomyocytes) using laser radiation; this study will help scientists to better understand the mechanisms of the heart and could ultimately provide a method of treating arrhythmia. The paper has been published in the journal PLOS ONE.

16 Apr 2016

New research suggests women need to wait until 30 to minimize career income losses

Working women who want to minimize career income losses related to motherhood should wait until they are about 30 years old to have their first children, suggests new research from Washington University in St. Louis.

15 Apr 2016

Expanding insurance coverage for elective single-embryo transfer could result in ideal pregnancy outcomes

Expanding insurance coverage for a type of in vitro fertilization known as elective single-embryo transfer could lead to improved health outcomes and lower health care costs, according to a newly published study that included researchers from the University of Colorado School of Medicine.

15 Apr 2016

M10 peptide could help protect systemic sclerosis patients against fibrotic damage

The results of preclinical studies by investigators at the Medical University of South Carolina (MUSC) reported in the April 2016 issue of Translational Research suggest that the M10 peptide could help protect against fibrotic damage in patients with systemic sclerosis, particularly in those who develop interstitial lung diseases (ILD), its deadliest complication.

15 Apr 2016

UNIGE researchers identify PIGG gene that plays crucial role in recessive disease

The objective of genetic medicine is to analyze all the genes that make up the human genome, in order to identify as many genetic diseases as possible. Indeed, each gene variation has the potential to trigger specific defects.

15 Apr 2016

Epigenomics receives FDA approval for Epi proColon®

Epigenomics AG, the German-American cancer molecular diagnostics company, has announced that the U.S. Food and Drug Administration (FDA) has approved the Company’s lead product, Epi proColon®, the first and only FDA-approved blood-based colorectal cancer screening test.

14 Apr 2016

Novel biochemical method can extend lifetime of implantable medical devices

Blood-contacting implantable medical devices, such as stents, heart valves, ventricular assist devices, and extracorporeal support systems, as well as vascular grafts and access catheters, are used worldwide to improve patients' lives. However, these devices are prone to failure due to the body's responses at the blood-material interface; clots can form and inflammatory reactions can prevent the device from performing as indicated. Currently, when this occurs, the only solution is to replace the device.

13 Apr 2016

New clinical data highlights potential of AB-PA01 to treat P. aeruginosa infections in CF patients

AmpliPhi Biosciences Corporation, a global leader in the development of bacteriophage-based antibacterial therapies to treat drug-resistant infections, presented data at the European Congress of Clinical Microbiology and Infectious Diseases summarizing both the in vitro and in vivo activity of its proprietary, investigational phage mix AB-PA01.

13 Apr 2016

Brazilian researchers reveal harmful effects of Zika virus in human neural stem cells, neurospheres

Brazilian researchers from the D'Or Institute for Research and Education (IDOR) and Federal University of Rio de Janeiro (UFRJ) have demonstrated the harmful effects of ZIKA virus (ZIKV) in human neural stem cells, neurospheres and brain organoids.

12 Apr 2016

Advanced assay offers better sensitivity for detecting a prion disease affecting elk

Transmissible spongiform encephalopathies (TSEs), or prion diseases, are a family of rare progressive, neurodegenerative illnesses that affect both humans and animals. TSE surveillance is important for public health and food safety because TSEs have the potential of crossing from animals to humans, as seen with the spread of mad cow disease, or bovine spongiform encephalopathy (BSE). A study in The Journal of Molecular Diagnostics describes an advanced assay that offers better sensitivity than currently available tests for detecting a prion disease affecting elk.

11 Apr 2016

Researchers identify influenza D antibodies in small ruminants

Although a new influenza virus, now called influenza D, was discovered first in pigs, researchers found it was more common in cattle. However, further research has identified antibodies to the virus in small ruminants, but not in poultry.

11 Apr 2016

Breast cancer medication letrozole could increase ovulation in women with PCOS

A medicine used in breast cancer treatment is now considered the best option for treating the most common cause of infertility.

6 Apr 2016

Innovative nano-therapy treatment can fight chronic inflammatory disorders, cancer

For an innovative treatment, which allows to selectively direct nanoparticles of iron oxide into cell targets in the blood to fight chronic inflammatory disorders or cancer that was successfully tested in a cell culture and animal models, Dr. Andrea de Vizcaya Ruiz, was awarded with the Innovation Award in Bionanotechnology Cinvestav-Neolpharma 2015.

6 Apr 2016

Study shows epidermal growth factor negatively regulates shedding of epithelial cells

The lining of the intestine is the most rapidly-renewing tissue in the body. Routine shedding of epithelial cells from this lining is a key element of tissue turnover, and is thus essential to maintaining optimal health. Altered shedding is associated with multiple disorders, ranging from inflammatory bowel disease (IBD) to colorectal cancer.

6 Apr 2016

One in 10 people in UK believed to be vitamin B12 deficient

One in 10 people in the UK are believed to be deficient in vitamin B12 – that’s an astonishing six million people suffering from the consequences of having less than the optimum amount of B12 in their system.

From BetterYou Ltd 4 Apr 2016

HDAC inhibitors could improve activity of immunotherapeutic antibodies in lung cancer patients

Several new immunotherapeutic antibodies that inhibit checkpoint receptors on T cells to restimulate the immune system to target tumors have been approved to treat advanced stage lung cancer and melanoma; however, only 20 percent of lung cancer patients show a response to these agents.

2 Apr 2016

in vitro News and Research

Zinc sparks help doctors choose best eggs to transfer during IVF

New blood treatment technology could reduce malaria risk following blood transfusions

Study finds links between phthalate exposure and obesity

Reducing hair loss during chemotherapy: an interview with Richard Paxman

Scientists find way to control behaviour of cardiomyocytes using laser radiation

New research suggests women need to wait until 30 to minimize career income losses

Expanding insurance coverage for elective single-embryo transfer could result in ideal pregnancy outcomes

M10 peptide could help protect systemic sclerosis patients against fibrotic damage

UNIGE researchers identify PIGG gene that plays crucial role in recessive disease

Epigenomics receives FDA approval for Epi proColon®

Novel biochemical method can extend lifetime of implantable medical devices

New clinical data highlights potential of AB-PA01 to treat P. aeruginosa infections in CF patients

Brazilian researchers reveal harmful effects of Zika virus in human neural stem cells, neurospheres

Advanced assay offers better sensitivity for detecting a prion disease affecting elk

Researchers identify influenza D antibodies in small ruminants

Breast cancer medication letrozole could increase ovulation in women with PCOS

Innovative nano-therapy treatment can fight chronic inflammatory disorders, cancer

Study shows epidermal growth factor negatively regulates shedding of epithelial cells

One in 10 people in UK believed to be vitamin B12 deficient

HDAC inhibitors could improve activity of immunotherapeutic antibodies in lung cancer patients

Driving innovation in drug discovery with in vitro biology solutions eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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