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Doing less exercise could deactivate a vital protein in the body, suggests study

Doing less exercise could deactivate a vital protein in the body, causing further inactivity and making exercise more difficult, new research suggests.

1 Mar 2022

Recombinant adenovirus vector vaccine generates mucosal antibodies against SARS-CoV-2

In a recent study posted to the bioRxiv* server, researchers assessed the immunogenicity of the self-developed recombinant adenovirus vector (rAd5) vaccine on macaques. They evaluated the efficacy of three candidate vaccines, ED88, ED90, and ED94, to select the most appropriate one for future development.

1 Mar 2022

Biophysical fitness profile of SARS-CoV-2 Delta variant

In a recent study posted to the bioRxiv* preprint server, researchers investigated the biophysical fitness landscape of the receptor-binding domain (RBD) of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Delta variant.

1 Mar 2022

Encouraging in vitro results with SARS-CoV-2-spike-specific polyclonal antibody fragments

In a recent study posted to the bioRxiv* preprint server, researchers demonstrated the potent neutralizing ability of a polyclonal equine antibody (Ab), FBR-002, against the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants of concern (VOCs), including Omicron.

28 Feb 2022

Scientists discover an innate form of immunological memory in the intestine

The innate immune system plays a crucial role in regulating host-microbe interactions, and especially in providing protection against pathogens that invade the mucosa.

28 Feb 2022

Microorganisms hindering cancer therapy have more influence than the beneficial ones, study says

Melanoma patients receiving therapy that helps their immune system kill cancer cells respond to treatment differently depending on the types of microbes in their gut, and new research suggests the microorganisms hindering therapy have more influence than the beneficial ones.

28 Feb 2022

Report provides a dire warning about the consequences of inaction against climate change

Human-induced climate change is causing dangerous and widespread disruption in nature and affecting the lives of billions of people around the world, despite efforts to reduce the risks.

28 Feb 2022

Metabolites could be used as biomarkers for forensic diagnosis of diabetes mellitus

Determining the cause of death is one of the most crucial and challenging parts of a forensic investigation.

28 Feb 2022

Harvard researcher develops new model system to illuminate the fundamentals of aging

Huge amounts of time and money have been devoted to finding treatments for diseases that become more common as we age, like cancer and Alzheimer's.

28 Feb 2022

New ultrasound scan can detect prostate cancer cases with good accuracy

An ultrasound scan can be used to detect cases of prostate cancer, according to new research.

28 Feb 2022

Study provides new understanding of the earliest molecular events in Type 1 Diabetes pathogenesis

For the first time, researchers have revealed that during the development of Type 1 Diabetes (T1D), when insulin-producing cells in the pancreas are under attack from T lymphocytes, the cells lining the pancreatic duct reprogram themselves in an attempt to suppress autoimmune T cell responses.

28 Feb 2022

First platform trial for ALS hopes to accelerate the development of effective treatments

A new paper in Annals of Neurology describes the approach, structure, and launch of the HEALEY ALS Platform Trial– the first platform trial for amyotrophic lateral sclerosis (ALS) designed to accelerate the development of effective and breakthrough treatments for people with the illness.

28 Feb 2022

Updated guideline released for managing antirheumatic drugs in patients undergoing hip or knee replacement

The American College of Rheumatology and the American Association of Hip and Knee Surgeons released a summary of their updated guideline for the Perioperative Management of Antirheumatic Medication in Patients with Rheumatic Diseases Undergoing Elective Total Hip or Total Knee Arthroplasty.

28 Feb 2022

New review highlights lack of women in leadership positions on cardiovascular clinical trials

Women remain underrepresented in leading cardiovascular clinical trials, which corresponds with underrepresentation and a lack of gender diversity among presenters at scientific meetings, according to a review published today in the Journal of the American College of Cardiology.

28 Feb 2022

Alcohol consumption may be a modifiable risk factor for age-related macular degeneration

Even though Dry January is over, new research suggests you may want to consider keeping the no-alcohol challenge going all year, especially if you're among the nearly 2 million Americans who have age-related macular degeneration (AMD), a sight-threatening eye condition.

28 Feb 2022

Researchers report a new, more efficient way to grow breast cancer models

For years, researchers at Huntsman Cancer Institute at the University of Utah have honed a process of developing breast cancer models using tumors donated by breast cancer patients, which they then implant into mice as a way to study the tumor's behavior.

28 Feb 2022

Researchers show a relationship between regionalized myocardial fibrosis and mitral valve prolapse

The larger the sail, the more wind it catches. But as that size increases, so does the stress experienced by each sheet and line connected to the canvas.

28 Feb 2022

Study reveals the thalamocortical mechanism for nostalgia-induced analgesia

Ever noticed that looking at photos of good times with family or friends diminishes the pain of your headache? Nostalgia has already been shown to be helpful with pain relief, and a new study has now revealed the thalamocortical mechanism for nostalgia-induced analgesia.

28 Feb 2022

Research shows intergenerational effects of preconception opioids in male offspring rats

New research from scientists at Cummings School of Veterinary Medicine at Tufts University suggests opioid use before pregnancy - even if not used during pregnancy itself - could result in a higher likelihood that a mother's male offspring will develop type 2 diabetes and metabolic syndrome, conditions that increase the risk of heart disease and stroke.

28 Feb 2022

Peer-led online communities effective in increasing HIV self-testing among MSM of color

A new University of California, Irvine-led study, called the HOPE (Harnessing Online Peer Education) HIV study, revealed that using peer-led online communities was successful in increasing HIV self-testing and reducing alcohol consumption among Latinx and African American MSM (men who have sex with men).

28 Feb 2022

Research News and Research

Doing less exercise could deactivate a vital protein in the body, suggests study

Recombinant adenovirus vector vaccine generates mucosal antibodies against SARS-CoV-2

Biophysical fitness profile of SARS-CoV-2 Delta variant

Encouraging in vitro results with SARS-CoV-2-spike-specific polyclonal antibody fragments

Scientists discover an innate form of immunological memory in the intestine

Microorganisms hindering cancer therapy have more influence than the beneficial ones, study says

Report provides a dire warning about the consequences of inaction against climate change

Metabolites could be used as biomarkers for forensic diagnosis of diabetes mellitus

Harvard researcher develops new model system to illuminate the fundamentals of aging

New ultrasound scan can detect prostate cancer cases with good accuracy

Study provides new understanding of the earliest molecular events in Type 1 Diabetes pathogenesis

First platform trial for ALS hopes to accelerate the development of effective treatments

Updated guideline released for managing antirheumatic drugs in patients undergoing hip or knee replacement

New review highlights lack of women in leadership positions on cardiovascular clinical trials

Alcohol consumption may be a modifiable risk factor for age-related macular degeneration

Researchers report a new, more efficient way to grow breast cancer models

Researchers show a relationship between regionalized myocardial fibrosis and mitral valve prolapse

Study reveals the thalamocortical mechanism for nostalgia-induced analgesia

Research shows intergenerational effects of preconception opioids in male offspring rats

Peer-led online communities effective in increasing HIV self-testing among MSM of color

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