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Vancomycin may not always be the best choice for treatment of bloodstream infections

The antibiotic most commonly prescribed to treat bloodstream infections in dialysis patients may not always be the best choice, according to a study appearing in an upcoming issue of the Journal of the American Society of Nephrology (JASN).

17 Aug 2012

Nostrum, VCU sign license agreement to develop inhaled dapsone for respiratory diseases

Virginia Commonwealth University and Nostrum Pharmaceuticals, LLC, are pleased to announce the signing of a license agreement for the development of inhaled dapsone for the treatment of respiratory diseases.

17 Aug 2012

Researchers use small molecule compound to generate reversible birth control in male mice

The development of a male contraceptive pill has long proven to be elusive, but findings from a new study may point scientists in the right direction to making oral birth control for men a reality.

17 Aug 2012

Springer publishes Principles of Research Methodology: A Guide for Clinical Investigators

How do you teach medical research? How do you design a good study or develop a workable hypothesis? How do you shape research to improve patient care? These and many more questions are addressed in an authoritative textbook detailing the clinical research process, written by researchers and clinicians at SUNY Downstate Medical Center and other institutions.

17 Aug 2012

Late heart rejection is in decline in children, mortality the same

The rate of heart transplant rejection after 1 year has decreased in pediatric patients in recent years compared with the early 1990s, report researchers who add that, despite this, mortality rates in these patients have stayed the same.

16 Aug 2012

Hemodialysis foot ulcer risk not confined to diabetes

Hemodialysis patients with and without diabetes are at risk for foot ulceration, say UK researchers who believe preventive resources must be directed toward both patient groups.

16 Aug 2012

Cortisol levels increased in youth at high risk for psychosis

Untreated young people at clinical high risk for psychosis have increased salivary cortisol levels compared with treated high-risk patients and mentally healthy individuals, study results show.

16 Aug 2012

First Edition: August 16, 2012

In this Kaiser Health News video, Insuring Your Health columnist Michelle Andrews answers a reader question about what you can do when insurance only covers a portion of an ambulance bill.

16 Aug 2012

Surgeons perform two TAVR procedures at Toledo Hospital

Minimally invasive surgery is one of the biggest trends in health care as a safer alternative to major surgery. One of the newest procedures, approved this year by the Food and Drug Administration, is Transcatheter Aortic Valve Replacement (TAVR).

16 Aug 2012

Study tracks effects of heavy PAE on growth and body composition throughout childhood

Although studies of alcohol's effects on fetal growth have consistently demonstrated deficits that persist through infancy, the data on long-term postnatal growth from human studies have been inconsistent. A new study of the effects of heavy prenatal alcohol exposure (PAE) on growth and body composition throughout childhood has found growth restrictions that persist through to nine years of age, as well as a delay in weight gain during infancy, both of which were exacerbated by iron deficiency.

16 Aug 2012

HCA's profit trail: Billing, staffing and ER care changes

HCA's robust profit growth has raised the value of the firms' holdings to nearly three and a half times their initial investment in the $33 billion deal. The financial performance has been so impressive that HCA has become a model for the industry.

16 Aug 2012

Acute stress modifies DNA methylation and activity of certain genes

Acute stress alters the methylation of the DNA and thus the activity of certain genes. This is reported by researchers at the Ruhr-Universität Bochum together with colleagues from Basel, Trier and London for the first time in the journal Translational Psychiatry. "The results provide evidence how stress could be related to a higher risk of mental or physical illness", says Prof. Dr. Gunther Meinlschmidt from the Clinic of Psychosomatic Medicine and Psychotherapy at the LWL University Hospital of the RUB.

16 Aug 2012

Tofacitinib drug shows promise against moderate-to-severe ulcerative colitis

An investigational drug currently under FDA review for the treatment of rheumatoid arthritis has now shown positive results in patients with moderate-to-severe ulcerative colitis, according to researchers at the University of California San Diego, School of Medicine.

16 Aug 2012

Intake of Mediterranean diet enriched with olive oil may increase serum osteocalcin concentrations

A study to be published in the Endocrine Society's Journal of Clinical Endocrinology and Metabolism (JCEM) shows consumption of a Mediterranean diet enriched with olive oil for two years is associated with increased serum osteocalcin concentrations, suggesting a protective effect on bone.

16 Aug 2012

Human milk oligosaccharides may reduce risk of mother-to-child HIV transmission

An international team of researchers has found that certain bioactive components found in human milk are associated with a reduced risk of HIV transmission from an HIV infected mother to her breast-fed infant. Their study will be published in the August 15 online edition of American Journal of Clinical Nutrition.

16 Aug 2012

Enzalutamide drug can extend life and improve QOL in men with advanced prostate cancer

The head of one of the UK's leading cancer research organisations has hailed a golden age in prostate cancer drug discovery as for the fourth time in two years results are published finding a new drug can significantly extend life.

16 Aug 2012

Malignant mesothelioma diagnosis with an E-nose: an interview with Associate Professor Deborah Yates, UNSW

Malignant mesothelioma is a rare tumor of the pleura which is the lining of the inside of the chest wall. It is highly linked with asbestos exposure.

16 Aug 2012

Physical activity effective in reducing sclerostin in premenopausal women

A study to be published in the Endocrine Society's Journal of Clinical Endocrinology and Metabolism (JCEM) suggests that physical activity for premenopausal women is very effective in reducing sclerostin-a known inhibitor of bone formation. In addition, physical training enhances IGF-1levels, which have a very positive effect on bone formation.

16 Aug 2012

CYCLOPS genes may serve as targets for cancer therapies

The genomic tumult within tumor cells has provided scientists at Dana-Farber Cancer Institute and the Broad Institute of MIT and Harvard with clues to an entirely new class of genes that may serve as an Achilles' heel for many forms of cancer.

16 Aug 2012

Computer-based partner violence screening does not improve QOL in women

In a study that included more than 2,700 women receiving care in primary care clinics, those who were screened for partner violence and received a partner violence resource list did not experience significant differences for several outcomes, including overall quality of life, general health, and recurrence of partner violence, compared to women who just received a partner violence resource list, according to a study in the August 15 issue of JAMA, a theme issue on violence and human rights.

16 Aug 2012

Hospital News and Research

Vancomycin may not always be the best choice for treatment of bloodstream infections

Nostrum, VCU sign license agreement to develop inhaled dapsone for respiratory diseases

Researchers use small molecule compound to generate reversible birth control in male mice

Springer publishes Principles of Research Methodology: A Guide for Clinical Investigators

Late heart rejection is in decline in children, mortality the same

Hemodialysis foot ulcer risk not confined to diabetes

Cortisol levels increased in youth at high risk for psychosis

First Edition: August 16, 2012

Surgeons perform two TAVR procedures at Toledo Hospital

Study tracks effects of heavy PAE on growth and body composition throughout childhood

HCA's profit trail: Billing, staffing and ER care changes

Acute stress modifies DNA methylation and activity of certain genes

Tofacitinib drug shows promise against moderate-to-severe ulcerative colitis

Intake of Mediterranean diet enriched with olive oil may increase serum osteocalcin concentrations

Human milk oligosaccharides may reduce risk of mother-to-child HIV transmission

Enzalutamide drug can extend life and improve QOL in men with advanced prostate cancer

Malignant mesothelioma diagnosis with an E-nose: an interview with Associate Professor Deborah Yates, UNSW

Physical activity effective in reducing sclerostin in premenopausal women

CYCLOPS genes may serve as targets for cancer therapies

Computer-based partner violence screening does not improve QOL in women

Improving healthcare sustainability through carbon data

Managing vibration in IVF laboratories

A New Approach to Preventing Bladder Cancer Recurrence

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